Abstract: Pyrrolidine main protease inhibitors are described that are effective as antiviral compounds.

Abstract: For manufacturing a Zn-air battery, a semi-liquid hydrogel including a polymer component comprising an irradiation activatable crosslinking initiator, and including an electrolyte component is deposited on a zinc anode. At least parts of the semi-liquid hydrogel are irradiated to activate the irradiation activatable crosslinking initiator for crosslinking the polymer component such as to transform the semi-liquid hydrogel into a drop-free yet sticky hydrogel. An air cathode is stuck to the drop-free yet sticky hydrogel.

Abstract: A portioning machine reducing bulk semi-viscous material portions to lesser semi-viscous material portions and methods of operating and using are provided. The apparatus includes one or more horizontal conveyor belts with a stream of bulk semi-viscous material portions thereon processing a bulk semi-viscous portion from the stream. Two or more vertical conveyors are provided communicating with an end of the one or more horizontal conveyors and entraining the bulk semi-viscous material portions there between.

Abstract: A curable silicone composition is disclosed. The curable silicone composition comprises: (A) a linear organopolysiloxane having at least two alkenyl groups and at least one aryl group in a molecule; (B) a branched organopolysiloxane represented by the average unit formula; (C) an organosiloxane having at least two silicon atom-bonded hydrogen atoms in a molecule; and (D) a hydrosilylation reaction catalyst. The curable silicone composition forms a cured product having good mechanical properties and good retention of transparency under conditions of high temperature.

Abstract: The invention is directed to a foodstuff extrusion portioning device and more specifically a cutter head assembly on such an extruder having a servo motor, a cutter shuttle coupled to a cutting element, a controller and being programmed via a product variable to provide a velocity profile. The cutter in the velocity profile has a first velocity and it reduces speed to a second velocity and goes more slowly through the last portion of the foodstuff. The at least two velocities being fully programmable and the controller can provide for instantaneous and additional programmed velocities throughout the cutting profile. The cutter further providing tilt control so it can drop the portion at the moment the portion detaches from the extruded foodstuff stream. It cuts and/or breaks off portions in a far more uniform and controllable manner to more accurately portion and better place the cut portions.

Abstract: A system for configuring a digital model of a building includes one or more memory devices having instructions stored thereon that, when executed by one or more processors, cause the one or more processors to perform operations. The operations include receiving project information including project specifications and drawings for the building and generating a digital model of the building based on the project information. Generating the digital model includes extracting, from the project information, one or more schedules, schedule notes, floor plans, or identified tags and associating each with a corresponding location in the project information. The operations may also include presenting, on a user interface, a portion of the project information in a base layer and presenting a model layer overlaying the base layer, which includes model objects representing each of the one or more schedules, schedule notes, floor plans, or identified tags in the digital model.

Abstract: A system and method that uses goo-location and a rules engine to facilitate compliance to federal, state, and local regulations as well as company policies across different jurisdictions that may have different compliance regulations. A mobile workforce may use the techniques herein to manage work assignments, report activities, and to manage and track time. This technology may be used, e.g., in the transportation industry, but is not limited to this industry.

Abstract: A system and method that uses geo-location and a rules engine to facilitate compliance to federal, state, and local regulations as well as company policies across different jurisdictions that may have different compliance regulations. A mobile workforce may use the techniques herein to manage work assignments, report activities, and to manage and track time. This technology may be used, e.g., in the transportation industry, but is not limited to this industry.

Abstract: A user-interactive tool for configuring a building equipment system includes one or more processors and one or more memory devices having instructions stored thereon that, when executed by the one or more processors, cause the one or more processors to perform operations including receiving a first user input including project information, obtaining equipment configuration data for a plurality of building equipment components capable of being included in the building equipment system based on the project information, receiving a second user input defining a configuration of the building equipment system, generating a predicted metric of the building equipment system based on the project information and the configuration of the building equipment system, displaying the predicted metric and a representative metric of a set of historical building equipment installation projects via a graphical user interface, and adjusting the predicted metric of the building equipment system based on the representative metric.

Abstract: A capacitance probe for determining the water cut or the amount of water in fluids. The probe includes at least a pair of electrodes. Each electrode includes a thin, pliable and conductive winding. The windings have a thin insulation layer or coating. The first electrode and the second electrode are configured to form a capacitance sensor that generates a signal related to the dielectric permittivity of a fluid flowing between the first electrode and the second electrode.

Abstract: A nuclear magnetic resonance (NMR) system is configured to detect combinatorial signatures stemming from homonuclear and heteronuclear J-couplings. The system comprises a pre-polarization system, a detector, and NMR electronics, wherein the detector includes an NMR magnet with a magnetic field of strength between 300 mT and 10 ?T.

Abstract: A powered balancing mobility device that can provide the user the ability to safely navigate expected environments of daily living including the ability to maneuver in confined spaces and to climb curbs, stairs, and other obstacles, and to travel safely and comfortably in vehicles. The mobility device can provide elevated, balanced travel.

Abstract: A silicone release coating composition and method for its preparation and use are described. A release coating prepared by curing the silicone release coating composition has high immediate release force (>50 g/in). A release liner including the release coating is suitable for use as a transfer liner in processes for making composites articles, such as aircraft parts.

Abstract: A method and apparatus for removal of tools, tubulars, casing, or other components that become stuck in a well. An anchor includes a mandrel, a carrier disposed on the mandrel and movable relative to the mandrel between an extended position and a retracted position, and an insert configured to engage an internal surface of a tubular, the insert movably disposed in the carrier as the carrier moves between the extended position and the retracted position. A method for anchoring a tool in a wellbore includes deploying the tool into the wellbore through a tubular to a first position, the tool comprising an anchor having a carrier and an insert disposed in the carrier, extending the carrier towards the tubular, and moving the insert relative to the carrier while engaging the inserts with the tubular, thereby anchoring the tool in the wellbore.

Abstract: Methods and apparatus for determining the water cut or the amount of water in fluids. The apparatus is inserted into a production logging tool that is lowered into the well. The apparatus includes a conductive winding which is configured as a first electrode. The winding includes a thin insulation coating or layer. The body of the tool is configured as a ground electrode. The primary electrode and the ground electrode are configured to form a capacitance sensor that generates a signal related to the dielectric permittivity of a fluid flowing between the primary electrode and the ground electrode.

Abstract: The invention concerns the field of microelectronics and relates to a three-dimensional component which, for example as a sensor, measures the direction of a property in a vector field. The object of the present solution is to specify a three-dimensional component that is capable of measuring and/or generating vector fields in multiple directions and/or simultaneously with low space requirements. The object is attained with a three-dimensional component for the uni-, bi-, tri- or multi-directional measurement and/or generation of vector fields, in which component at least one element made of material systems in present on a three-dimensional carrier made of at least one carrier material, which element measures and/or generates at least one vector field in at least one direction in the spatial position of the element on, against and/or in the carrier.

Abstract: A powered balancing mobility device that can provide the user the ability to safely navigate expected environments of daily living including the ability to maneuver in confined spaces and to climb curbs, stairs, and other obstacles, and to travel safely and comfortably in vehicles. The mobility device can provide elevated, balanced travel.

Abstract: The present invention provides for compounds of Formula (I) wherein R1, R2, R3, m and n have any of the values defined in the specification, and pharmaceutically acceptable salts thereof, pharmaceutical compositions comprising the same, and methods of treating cystic fibrosis by administering a compound of the invention.

Abstract: A system and method that uses geo-location and a rules engine to facilitate compliance to federal, state, and local regulations as well as company policies across different jurisdictions that may have different compliance regulations. A mobile workforce may use the techniques herein to manage work assignments, report activities, and to manage and track time. This technology may be used, e.g., in the transportation industry, but is not limited to this industry.

Abstract: An overlay surface for a user interface of a device comprises a lower light-diffusing semitransparent layer affixed to an upper transparent layer. Graphics printed on the bottom surface of the transparent layer are protected from wear by the overlying transparent layer, while light sources back-illuminating the graphics from below are diffused by the semitransparent layer before they reach the graphics. The graphics of the surface may be provided by an opaque mask having transparent or translucent cutouts. The multilayer surface enables the graphics to be evenly back-illuminated while at the same time being protected from external wear without the need for additional light-diffusing elements such as light pipes.