Patents by Inventor Gabriel Lopez
Gabriel Lopez has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20240150511Abstract: A weak base anion resin has alkylamine segments covalently bound to cross-linking segments, the alkylamine segments being selected from a group consisting of: vinylamine, N-methylvinylamine, N,N-dimethylvinylamine, N-methyl-N-ethylvinylamine, and N,N-diethylvinylamine, and the weak base anion resin including ions adsorbed to the alkylamine segments. A method for ion exchange includes providing a weak base anion resin, contacting the weak base anion resin with a solution containing ions to one of capture or adsorb ions from solution to the weak base anion resin, and regenerating the weak base anion resin. A method to capture and release an acid gas includes providing a weak base anion resin, contacting the weak base anion resin with a gas including an acid gas to one of capture or adsorb the acid gas from the gas to the weak base anion resin, and regenerating the weak base anion resin to release the acid gas.Type: ApplicationFiled: November 2, 2023Publication date: May 9, 2024Inventors: JONATHAN BACHMAN, MAHATI CHINTAPALLI, GABRIEL IFTIME, IGNACIO LOPEZ PENA, FATEMEH OSTADHOSSEIN, ARAVINDH RAJAN, RAVI NEELAKANTAN
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Publication number: 20240130765Abstract: One aspect of the disclosure relates to an extramedullary biocompatible implant for moving bone in a patient's body. In some cases, the implant includes: a first plate configured to be attached to bone at a first location; a second plate configured to be attached to bone at a second location; and a distractor extending from the first plate and being at least partially contained within the second plate, where the distractor houses a drive system including a driver and a gear system coupled with the driver, and where the drive system is configured to cause translation of the second plate relative to the first plate.Type: ApplicationFiled: October 20, 2022Publication date: April 25, 2024Inventors: Jorge Lopez Camacho, Shawn Placie, Nathan Meyer, Emmon Chen, Gabriel Buenviaje, Woong Kim
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Integrated circuit comprising a single photon avalanche diode and corresponding manufacturing method
Patent number: 11949035Abstract: A single photon avalanche diode (SPAD) includes a PN junction in a semiconductor well doped with a first type of dopant. The PN junction is formed between a first region doped with the first type of dopant and a second region doped with a second type of dopant opposite to the first type of dopant. The first doped region is shaped so as to incorporate local variations in concentration of dopants that are configured, in response to a voltage between the second doped region and the semiconductor well that is greater than or equal to a level of a breakdown voltage of the PN junction, to generate a monotonic variation in the electrostatic potential between the first doped region and the semiconductor well.Type: GrantFiled: December 9, 2021Date of Patent: April 2, 2024Assignees: STMicroelectronics (Crolles 2) SAS, STMicroelectronics (Research & Development) LimitedInventors: Denis Rideau, Dominique Golanski, Alexandre Lopez, Gabriel Mugny -
Patent number: 11940008Abstract: Rolling-element bearing for a turbomachine of an aircraft, comprising an inner ring (3) defining a first raceway (112), and an outer ring (4) defining a second raceway (124), characterized in that the bearing has at least one loop circuit (21, 22) for forced recirculation of lubricant, this loop circuit comprising a first recirculation circuit (21) comprising at least one lubricant inlet (1200) located on the second raceway (124), and connected by at least one duct (120, 166) created in the outer ring (4) to at least one lubricant outlet (1661) which discharges into a second recirculation circuit (22) of the loop circuit (21, 22), this second recirculation circuit (22) comprising at least one duct (152, 1134, 1136; 1135, 1136) created in the inner ring (3).Type: GrantFiled: July 9, 2020Date of Patent: March 26, 2024Assignee: SAFRAN POWER UNITSInventors: Serge Marie Gabriel Cot, Jean-Paul Salvador Lopez, Stephane Chevalier
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Patent number: 11929538Abstract: A RF dielectric filter comprising a block of dielectric material including top and bottom exterior longitudinal surfaces and side exterior surfaces covered with a layer of conductive material. RF signal input/output pads are located at opposed ends of the block. Each of the RF signal input/output pads comprises a strip of conductive material bridging between the bottom exterior surface and the side exterior surface. A strip or region of dielectric material surrounds all the sides of the elongate strip of conductive material except for one end of the strip of conductive material on the side exterior surface which is in a direct unitary coupling relationship with the remainder of the conductive material on the side exterior surface. In one embodiment, the strip or region of dielectric material is generally U-shaped and can vary in width.Type: GrantFiled: December 15, 2021Date of Patent: March 12, 2024Assignee: CTS CorporationInventors: Dong Jing, Gabriel Lopez, Nam Phan
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Patent number: 11883758Abstract: A toy playset is presented herein. The toy playset includes a base section, a track section configured to receive a toy vehicle, and a biasing member coupled to the base section and to the track section. The biasing member is configured to bias the base section and the track section away from one another, and the biasing member is configured to flex to enable the base section and the track section to move relative to one another.Type: GrantFiled: April 17, 2023Date of Patent: January 30, 2024Assignee: Mattel, Inc.Inventors: Scott Cody, Gabriel De La Torre, Gabriel Lopez
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Publication number: 20230416307Abstract: The present disclosure provides methods and compositions for production of recombinant viral vectors, such as adeno-associated virus (AAV) vectors or lentiviral vectors, in host cells using engineered cyclic peptides that increase viral titer and transduction efficiency of viral vector compositions. The present disclosure also provides methods for selecting genetically encoded, endogenously expressed cyclic peptides that enhance viral vector manufacturability.Type: ApplicationFiled: June 22, 2023Publication date: December 28, 2023Applicant: Synvivia, Inc.Inventors: Gabriel Lopez, Charlie Huang
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Publication number: 20230167453Abstract: Provided herein are RNA aptamers targeting CD5L. Further provided herein are methods of use thereof for the treatment of a disease or disorder, such as cancer.Type: ApplicationFiled: April 1, 2021Publication date: June 1, 2023Applicants: Board of Regents, The University of Texas System, Consiglio Nazionale delle RicercheInventors: Anil K. SOOD, Paola AMERO, Gabriel LOPEZ-BERESTEIN, Vittorio DE FRANCISCIS
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Publication number: 20230105226Abstract: The present invention relates to a broad-spectrum biocidal composition, with fungicidal and bactericidal activity, containing metal or metal oxide nanoparticles, polymeric thickeners, plant extracts, surfactants, and additives in an aqueous solvent, as well as the method for in situ production of said metal nanoparticles under controlled operating conditions: concentration, volumetric ratio, time, agitation, temperature, and pH, using plant extracts as reducing agents.Type: ApplicationFiled: February 8, 2022Publication date: April 6, 2023Inventors: Julián Mauricio GUERRERO RODRÍGUEZ, José Gabriel LÓPEZ ORTIZ, Maria Fernanda ROMERO PINEDA, Debora Alcida NABARLATZ, Leydy Paola BARRERA LEMUS
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Patent number: 11534697Abstract: An improved toy vehicle playset contains a tower and multiple track portions coupled to the tower that provide a path for toy vehicles to descend from the top of the tower. The tower may include an elevator mechanism for transporting toy vehicles up the tower and an interactive feature that is configured to interact with descending toy vehicles along the track portions. The descent of the toy vehicles may trigger the interactive feature to also descend from the top of the tower, where the descending interactive feature may attempt to impede or stop the descending toy vehicles along the track portions. In some embodiments, the one or more towers may further include platforms configured to store and retain a plurality of toy vehicles, mechanisms that trigger one or more toy vehicles to be launched from the platforms, and mechanisms for diverting toy vehicles onto the platforms.Type: GrantFiled: February 4, 2021Date of Patent: December 27, 2022Assignee: Mattel, Inc.Inventor: Gabriel Lopez
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Publication number: 20220380766Abstract: Provided herein are DNA aptamers targeting AXL receptor kinase. The DNA aptamers may comprise a thiophosphate backbone and be chemically modified. Further provided herein are methods of use thereof for the treatment of a disease or disorder, such as cancer.Type: ApplicationFiled: December 16, 2019Publication date: December 1, 2022Applicants: Board of Regents, The University of Texas System, Consiglio Nazionale delle RicercheInventors: Gabriel LOPEZ-BERESTEIN, Paola AMERO, Cristian RODRIGUEZ-AGUAYO, Rahul MITRA, Anil K. SOOD, Vittorio DE FRANCISCIS, David VOLK, Lokesh Ganesh L. RAO
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Publication number: 20220200113Abstract: A RF dielectric filter comprising a block of dielectric material including top and bottom exterior longitudinal surfaces and side exterior surfaces covered with a layer of conductive material. RF signal input/output pads are located at opposed ends of the block. Each of the RF signal input/output pads comprises a strip of conductive material bridging between the bottom exterior surface and the side exterior surface. A strip or region of dielectric material surrounds all the sides of the elongate strip of conductive material except for one end of the strip of conductive material on the side exterior surface which is in a direct unitary coupling relationship with the remainder of the conductive material on the side exterior surface. In one embodiment, the strip or region of dielectric material is generally U-shaped and can vary in width.Type: ApplicationFiled: December 15, 2021Publication date: June 23, 2022Applicant: CTS CorporationInventors: Dong Jing, Gabriel Lopez, Nam Phan
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Patent number: 11225657Abstract: Synthetic auxotrophs with one or more ligand-dependent essential gene functions and methods of production that can be used for biosafety. The ligand-dependent function of an essential gene product can be produced by a series of mutations in the ORF of an essential gene; N, C, or insertional fusions of ligand-binding domains with essential genes or an engineered ligand-dependent intein splicing to alter essential gene function. A positive and/or negative selection can be used to identify auxotrophs from created mutant libraries. The positive selection is performed by growing a mutant library in conditions where growth or viability depends on the function of mutagenized essential genes. The negative selection eliminates constitutively growing cells that do not require a ligand for growth by growing the library in the absence of complementing ligand and in conditions where growing cells are eliminated. Desirable phenotypes are collected after the selections.Type: GrantFiled: November 27, 2017Date of Patent: January 18, 2022Assignee: THE REGENTS OF THE UNIVERSITY OF CALIFORNIAInventors: John C. Anderson, Gabriel Lopez
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Publication number: 20210245069Abstract: An improved toy vehicle playset contains a tower and multiple track portions coupled to the tower that provide a path for toy vehicles to descend from the top of the tower. The tower may include an elevator mechanism for transporting toy vehicles up the tower and an interactive feature that is configured to interact with descending toy vehicles along the track portions. The descent of the toy vehicles may trigger the interactive feature to also descend from the top of the tower, where the descending interactive feature may attempt to impede or stop the descending toy vehicles along the track portions. In some embodiments, the one or more towers may further include platforms configured to store and retain a plurality of toy vehicles, mechanisms that trigger one or more toy vehicles to be launched from the platforms, and mechanisms for diverting toy vehicles onto the platforms.Type: ApplicationFiled: February 4, 2021Publication date: August 12, 2021Inventor: Gabriel LOPEZ
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Patent number: 10874622Abstract: Disclosed are nanoparticles for the delivery of a therapeutic agent or a diagnostic agent to a subject that include a chitosan and a polyphosphate, wherein the chitosan nanoparticles are coated with polylactic acid. Methods of delivering a therapeutic agent or a diagnostic agent to a subject for the treatment or prevention of a disease are also disclosed. For example, the treatment of ovarian cancer in a subject by inhibiting the expression of ZNF034 is disclosed.Type: GrantFiled: June 23, 2016Date of Patent: December 29, 2020Assignee: Board of Regents, The University of Texas SystemInventors: Burcu Aslan, Gabriel Lopez-Berestein, Anil K. Sood
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Publication number: 20200355677Abstract: Acoustically responsive particles and methods are provided for their use. Methods are provided for making and using tunable, monodisperse acoustically responsive particles and negative contrast acoustic particles, wherein the particles can contain a functional group available for covalent modification.Type: ApplicationFiled: July 29, 2020Publication date: November 12, 2020Inventors: Leah M Johnson, Gabriel Lopez, Lu Gao, Charles Wyatt Shields, IV
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Publication number: 20200069594Abstract: Provided herein are lipid-based nanoparticles (e.g., exosomes) having (a) a core comprising a cationic polymer and a therapeutic agent (e.g., a therapeutic protein, an antibody, an inhibitory RNA, and/or a small molecule drug) and (b) a lipid coating comprising an exosomes-derived membrane. Furthermore, the present invention provides methods of producing such nanoparticles as well as methods for use of such lipid-based nanoparticles in therapy.Type: ApplicationFiled: December 8, 2017Publication date: March 5, 2020Applicant: Board of Regents, The University of Texas SystemInventors: Anil K. SOOD, Sherry Y. WU, Gabriel LOPEZ-BERESTEIN
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Publication number: 20180169029Abstract: Disclosed are nanoparticles for the delivery of a therapeutic agent or a diagnostic agent to a subject that include a chitosan and a polyphosphate, wherein the chitosan nanoparticles are coated with polylactic acid. Methods of delivering a therapeutic agent or a diagnostic agent to a subject for the treatment or prevention of a disease are also disclosed. For example, the treatment of ovarian cancer in a subject by inhibiting the expression of ZNF034 is disclosed.Type: ApplicationFiled: June 23, 2016Publication date: June 21, 2018Inventors: Burcu ASLAN, Gabriel LOPEZ-BERESTEIN, Anil K. SOOD
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Publication number: 20180155711Abstract: Synthetic auxotrophs with one or more ligand-dependent essential gene functions and methods of production that can be used for biosafety. The ligand-dependent function of an essential gene product can be produced by a series of mutations in the ORF of an essential gene; N, C, or insertional fusions of ligand-binding domains with essential genes or an engineered ligand-dependent intein splicing to alter essential gene function. A positive and/or negative selection can be used to identify auxotrophs from created mutant libraries. The positive selection is performed by growing a mutant library in conditions where growth or viability depends on the function of mutagenized essential genes. The negative selection eliminates constitutively growing cells that do not require a ligand for growth by growing the library in the absence of complementing ligand and in conditions where growing cells are eliminated. Desirable phenotypes are collected after the selections.Type: ApplicationFiled: November 27, 2017Publication date: June 7, 2018Applicant: THE REGENTS OF THE UNIVERSITY OF CALIFORNIAInventors: John C. Anderson, Gabriel Lopez
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Publication number: 20160375050Abstract: Disclosed are nanoparticles for the delivery of a therapeutic agent or a diagnostic agent to a subject that include a chitosan and a polyphosphate, wherein the weight ratio of the chitosan to the polyphosphate is about 1.0 or greater and the weight ratio of the polyphosphate to the therapeutic agent or diagnostic agent is about 15.0 or less. Also disclosed are nanoparticles that include a chitosan and an inhibitor of enhancer of Zeste homologue 2 (EZH2). Methods of delivering a therapeutic agent or a diagnostic agent to a subject for the treatment or prevention of a disease and methods of predicting prognosis of ovarian cancer in a subject that involve determining the expression and/or function of EZH2 in the subject are also disclosed.Type: ApplicationFiled: September 13, 2016Publication date: December 29, 2016Applicant: The Board of Regents of the University of Texas SystemInventors: Gabriel LOPEZ-BERESTEIN, Eylem GÜVEN, Angela SANGUINO, Anil K. SOOD, Emir Baki DENKBAS