Patents by Inventor Gabriel Pascual

Gabriel Pascual has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • MATERIALS AND METHODS OF IL-1BETA BINDING PROTEINS
    Publication number: 20230227545
    Abstract: Provided herein, in certain aspects, are antibodies that bind to IL-1? and compositions comprising the antibodies. Methods of making and using the antibodies are also provided.
    Type: Application
    Filed: January 6, 2023
    Publication date: July 20, 2023
    Applicant: JOHNSON & JOHNSON ENTERPRISE INNOVATION INC.
    Inventors: Gabriel PASCUAL, Sagit HINDI, Suresh Kumar SWAMINATHAN
  • Antibodies and antigen-binding fragments that specifically bind to microtubule-associated protein tau
    Patent number: 11472869
    Abstract: The invention relates to antibodies and antigen-binding fragments that specifically bind to microtubule-associated protein tau. The invention also relates to diagnostic, prophylactic and therapeutic methods using anti-tau antibodies.
    Type: Grant
    Filed: July 17, 2019
    Date of Patent: October 18, 2022
    Assignee: Janssen Vaccines & Prevention B.V.
    Inventors: Jehangir Wadia, Gabriel Pascual, Robert Anthony Williamson, Katarina Radosevic, Jaap Goudsmit
  • ANTI-SYNUCLEIN ANTIBODIES
    Publication number: 20210347868
    Abstract: Anti-alpha-synuclein antibodies and antigen-binding fragments thereof are described. Also described are nucleic acids encoding the antibodies, compositions comprising the antibodies, and methods of producing the antibodies and using the antibodies for treating or preventing diseases characterized by Lewy bodies or alpha-synuclein aggregation.
    Type: Application
    Filed: October 17, 2019
    Publication date: November 11, 2021
    Inventors: Gabriel PASCUAL, Adrian APETRI, Xinji LI
  • ANTIBODIES AND ANTIGEN-BINDING FRAGMENTS THAT SPECIFICALLY BIND TO MICROTUBULE-ASSOCIATED PROTEIN TAU
    Publication number: 20200399350
    Abstract: The invention relates to antibodies and antigen-binding fragments that specifically bind to microtubule-associated protein tau. The invention also relates to diagnostic, prophylactic and therapeutic methods using anti-tau antibodies.
    Type: Application
    Filed: July 17, 2019
    Publication date: December 24, 2020
    Inventors: Jehangir WADIA, Gabriel PASCUAL, Robert Anthony WILLIAMS, Katarina RADOSEVIC, Jaap GOUDSMIT
  • Antibodies and antigen-binding fragments that specifically bind to microtubule-associated protein tau
    Patent number: 10562963
    Abstract: The disclosure relates to antibodies and antigen-binding fragments that specifically bind to microtubule-associated protein tau. The disclosure also relates to diagnostic, prophylactic and therapeutic methods using anti-tau antibodies.
    Type: Grant
    Filed: April 3, 2019
    Date of Patent: February 18, 2020
    Assignee: JANSSEN VACCINES & PREVENTION, B.V.
    Inventors: Jehangir Wadia, Gabriel Pascual, Robert Anthony Williamson, Katarina Radosevic, Jaap Goudsmit
  • ANTIBODIES AND ANTIGEN-BINDING FRAGMENTS THAT SPECIFICALLY BIND TO MICROTUBULE-ASSOCIATED PROTEIN TAU
    Publication number: 20190292249
    Abstract: The disclosure relates to antibodies and antigen-binding fragments that specifically bind to microtubule-associated protein tau. The disclosure also relates to diagnostic, prophylactic and therapeutic methods using anti-tau antibodies.
    Type: Application
    Filed: April 3, 2019
    Publication date: September 26, 2019
    Inventors: Jehangir WADIA, Gabriel PASCUAL, Robert Anthony WILLIAMSON, Katarina RADOSEVIC, Jaap GOUDSMIT
  • Antibodies and antigen-binding fragments that specifically bind to microtubule-associated protein tau
    Patent number: 10400034
    Abstract: The disclosure relates to antibodies and antigen-binding fragments that specifically bind to microtubule-associated protein tau. The disclosure also relates to diagnostic, prophylactic and therapeutic methods using anti-tau antibodies.
    Type: Grant
    Filed: June 26, 2015
    Date of Patent: September 3, 2019
    Assignee: JANSSEN VACCINES & PREVENTION, B.V.
    Inventors: Jehangir Wadia, Gabriel Pascual, Robert Anthony Williamson, Katarina Radosevic, Jaap Goudsmit
  • Antibodies and antigen-binding fragments that specifically bind to microtubule-associated protein tau
    Patent number: 10301379
    Abstract: The disclosure relates to antibodies and antigen-binding fragments that specifically bind to microtubule-associated protein tau. The disclosure also relates to diagnostic, prophylactic and therapeutic methods using anti-tau antibodies.
    Type: Grant
    Filed: June 26, 2015
    Date of Patent: May 28, 2019
    Assignee: JANSSEN VACCINES & PREVENTION B.V.
    Inventors: Jehangir Wadia, Gabriel Pascual, Robert Anthony Williamson, Katarina Radosevic, Jaap Goudsmit
  • Human antibodies binding to RSV G protein
    Patent number: 10196438
    Abstract: The disclosure relates to isolated antibodies and antigen-binding fragments that bind to the G protein of RSV and which are capable of neutralizing RSV A and B subtypes, and the use thereof in the diagnosis, prophylaxis, and/or treatment of RSV infections.
    Type: Grant
    Filed: April 14, 2014
    Date of Patent: February 5, 2019
    Assignee: Janssen Vaccines & Prevention B.V.
    Inventors: Jehangir Wadia, Robert Anthony Williamson, Johannes P. M. Langedijk, Gabriel Pascual, Angelique Van 'T Wout
  • Human antibodies binding to RSV G proteins
    Patent number: 10035842
    Abstract: The disclosure provides isolated antibodies and antigen-binding fragments that bind to the G protein of RSV and which are capable of neutralizing RSV.
    Type: Grant
    Filed: April 14, 2014
    Date of Patent: July 31, 2018
    Assignee: JANSSEN VACCINES & PREVENTION B.V.
    Inventors: Jehangir Wadia, Robert Anthony Williamson, Johannes P. M. Langedijk, Gabriel Pascual, Angelique Van 't Wout
  • Anti-human Respiratory Syncytial Virus (RSV) antibodies and methods of use
    Patent number: 9988437
    Abstract: Provided herein are antibodies or antigen-binding fragments thereof that immunospecifically bind to the fusion (F) protein of Respiratory Syncytial Virus (RSV). Also provided are methods for of prevention, treatment and diagnosis of viral infection and/or the treatment of one more symptoms of RSV-mediated disease. Methods of generating antibodies that immunospecifically bind RSV F protein also are provided.
    Type: Grant
    Filed: March 22, 2016
    Date of Patent: June 5, 2018
    Assignee: Janssen Vaccines & Prevention B.V.
    Inventors: Robert Anthony Williamson, Jehangir Wadia, Gabriel Pascual, Elissa Keogh
  • ANTIBODIES AND ANTIGEN-BINDING FRAGMENTS THAT SPECIFICALLY BIND TO MICROTUBULE-ASSOCIATED PROTEIN TAU
    Publication number: 20170210787
    Abstract: The disclosure relates to antibodies and antigen-binding fragments that specifically bind to microtubule-associated protein tau. The disclosure also relates to diagnostic, prophylactic and therapeutic methods using anti-tau antibodies.
    Type: Application
    Filed: June 26, 2015
    Publication date: July 27, 2017
    Applicant: Janssen Vaccines & Prevention B.V.
    Inventors: Jehangir Wadia, Gabriel Pascual, Robert Anthony Williamson, Katarina Radosevic, Jaap Goudsmit
  • ANTIBODIES AND ANTIGEN-BINDING FRAGMENTS THAT SPECIFICALLY BIND TO MICROTUBULE-ASSOCIATED PROTEIN TAU
    Publication number: 20170152307
    Abstract: The disclosure relates to antibodies and antigen-binding fragments that specifically bind to microtubule-associated protein tau. The disclosure also relates to diagnostic, prophylactic and therapeutic methods using anti-tau antibodies.
    Type: Application
    Filed: June 26, 2015
    Publication date: June 1, 2017
    Applicant: Janssen Vaccines & Prevention B.V.
    Inventors: Jehangir Wadia, Gabriel Pascual, Robert Anthony Williamson, Katarina Radosevic, Jaap Goudsmit
  • Anti-human respiratory syncytial virus (RSV) antibodies and methods of use
    Patent number: 9403900
    Abstract: Provided herein are antibodies or antigen-binding fragments thereof that immunospecifically bind to the fusion (F) protein of Respiratory Syncytial Virus (RSV). Also provided are methods for of prevention, treatment and diagnosis of viral infection and/or the treatment of one more symptoms of RSV-mediated disease. Methods of generating antibodies that immunospecifically bind RSV F protein also are provided.
    Type: Grant
    Filed: June 5, 2014
    Date of Patent: August 2, 2016
    Assignee: Crucell Holland B.V.
    Inventors: Robert Anthony Williamson, Jehangir Wadia, Gabriel Pascual, Elissa Keogh
  • ANTI-HUMAN RESPIRATORY SYNCYTIAL VIRUS (RSV) ANTIBODIES AND METHODS OF USE
    Publication number: 20160194383
    Abstract: Provided herein are antibodies or antigen-binding fragments thereof that immunospecifically bind to the fusion (F) protein of Respiratory Syncytial Virus (RSV). Also provided are methods for of prevention, treatment and diagnosis of viral infection and/or the treatment of one more symptoms of RSV-mediated disease. Methods of generating antibodies that immunospecifically bind RSV F protein also are provided.
    Type: Application
    Filed: March 22, 2016
    Publication date: July 7, 2016
    Inventors: Robert Anthony Williamson, Jehangir Wadia, Gabriel Pascual, Elissa Keogh
  • Antibodies against human respiratory syncytial virus (RSV) and methods of use
    Patent number: 9365638
    Abstract: Provided herein are antibodies or antigen-binding fragments thereof that immunospecifically bind to the fusion (F) protein of Respiratory Syncytial Virus (RSV). Also provided are methods for of prevention, treatment and diagnosis of viral infection and/or the treatment of one more symptoms of RSV-mediated disease. Methods of generating antibodies that immunospecifically bind RSV F protein also are provided.
    Type: Grant
    Filed: September 10, 2013
    Date of Patent: June 14, 2016
    Assignee: Crucell Holland B. V.
    Inventors: Robert Anthony Williamson, Jehangir Wadia, Gabriel Pascual, Elissa Keogh
  • HUMAN ANTIBODIES BINDING TO RSV G PROTEIN
    Publication number: 20160145321
    Abstract: The disclosure relates to isolated antibodies and antigen-binding fragments that bind to the G protein of RSV and which are capable of neutralizing RSV A and B subtypes, and the use thereof in the diagnosis, prophylaxis, and/or treatment of RSV infections.
    Type: Application
    Filed: April 14, 2014
    Publication date: May 26, 2016
    Applicant: CRUCELL HOLLAND B.V.
    Inventors: Jehangir Wadia, Robert Anthony Williamson, Johannes P.M. Langedijk, Gabriel Pascual, Angelique Van 'T Wout
  • HUMAN ANTIBODIES BINDING TO RSV G PROTEINS
    Publication number: 20160145322
    Abstract: The disclosure provides isolated antibodies and antigen-binding fragments that bind to the G protein of RSV and which are capable of neutralizing RSV.
    Type: Application
    Filed: April 14, 2014
    Publication date: May 26, 2016
    Applicant: CRUCELL HOLLAND B. V.
    Inventors: Jehangir Wadia, Robert Anthony Williamson, Johannes P.M. Langedijk, Gabriel Pascual, Angelique Van 't Wout
  • Anti-human respiratory syncytial virus (RSV) antibodies and methods of use
    Patent number: 9139642
    Abstract: Provided herein are antibodies or antigen-binding fragments thereof that immunospecifically bind to the fusion (F) protein of Respiratory Syncytial Virus (RSV). Also provided are methods for of prevention, treatment and diagnosis of viral infection and/or the treatment of one more symptoms of RSV-mediated disease. Methods of generating antibodies that immunospecifically bind RSV F protein also are provided.
    Type: Grant
    Filed: July 8, 2011
    Date of Patent: September 22, 2015
    Assignee: Crucell Holland B.V.
    Inventors: Robert Anthony Williamson, Jehangir Wadia, Gabriel Pascual, Elissa Keogh
  • ANTI-HUMAN RESPIRATORY SYNCYTIAL VIRUS (RSV) ANTIBODIES AND METHODS OF USE
    Publication number: 20140363427
    Abstract: Provided herein are antibodies or antigen-binding fragments thereof that immunospecifically bind to the fusion (F) protein of Respiratory Syncytial Virus (RSV). Also provided are methods for of prevention, treatment and diagnosis of viral infection and/or the treatment of one more symptoms of RSV-mediated disease. Methods of generating antibodies that immunospecifically bind RSV F protein also are provided.
    Type: Application
    Filed: June 5, 2014
    Publication date: December 11, 2014
    Inventors: Robert Anthony Williamson, Jehangir Wadia, Gabriel Pascual, Elissa Keogh