Patents by Inventor Gabriel Rusanescu

Gabriel Rusanescu has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Method of selecting agents for the treatment of pain using neuronal differentiation
    Publication number: 20190365856
    Abstract: The present invention is based on the seminal concept of treating pain by promoting neuronal differentiation. The invention provides a screening method for the selection of agents for the purpose of treating pain, utilizing neuronal differentiation as selection criteria. Methods and libraries available for screening for the selection of candidate agents are provided.
    Type: Application
    Filed: August 16, 2019
    Publication date: December 5, 2019
    Inventor: Gabriel Rusanescu
  • Method of treating pain using agents that promote neuronal differentiation
    Patent number: 10398760
    Abstract: The present invention is based on the seminal concept of treating pain by promoting neuronal differentiation. The invention provides a method of treating pain utilizing agents that induce neuronal differentiation by activating specific receptors. The invention also provides a method of screening of agents for the purpose of use in treating pain, based on their neuronal differentiation activity.
    Type: Grant
    Filed: August 27, 2016
    Date of Patent: September 3, 2019
    Inventor: Gabriel Rusanescu
  • Method of treating pain using agents that promote neuronal differentiation
    Publication number: 20180000897
    Abstract: The present invention is based on the seminal concept of treating pain by promoting neuronal differentiation. The invention provides a method of treating pain utilizing agents that induce neuronal differentiation by activating specific receptors. The invention also provides a method of screening of agents for the purpose of use in treating pain, based on their neuronal differentiation activity.
    Type: Application
    Filed: August 27, 2016
    Publication date: January 4, 2018
    Inventor: Gabriel Rusanescu
  • Method of inducing cellular differentiation using the Notch3 receptor intracellular domain
    Publication number: 20160032244
    Abstract: The present invention relates to the intracellular domain of Notch3 that can activate signaling and initiate transcription, thereby initiating cellular differentiation in general, and neuronal differentiation in particular. The present invention includes the use of polynucleotide sequences that code, entirely or partially, for the intracellular domain of Notch3, for the purpose of inducing cellular differentiation. The present invention includes the use of Notch3 intracellular domain polynucleotide or polypeptide sequences for the purpose of treating diseases or disorders, by inducing cellular differentiation.
    Type: Application
    Filed: August 3, 2015
    Publication date: February 4, 2016
    Inventor: Gabriel Rusanescu