Patents by Inventor Gabriela D.C. Denning

Gabriela D.C. Denning has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Clotting Factor Variants and Their Use
    Publication number: 20230374484
    Abstract: Disclosed herein are novel variants of clotting factor IX and their use, for example, in methods of treating a subject with a clotting disorder, such as hemophilia A or hemophilia B.
    Type: Application
    Filed: December 29, 2021
    Publication date: November 23, 2023
    Inventors: Gabriela D.C. Denning, Christopher B. Doering, Harrison Brown, Kristopher Knight, Christopher Coyle, Harold Trent Spencer
  • High yield suspension cell line, system and method for making same
    Patent number: 8986991
    Abstract: A system and method of adapting host cells to suspension cell culture and suspension cell lines ATCC PTA-12593 and ATCC PTA-12461 produced thereby are disclosed. The method includes the serial replating of substantially undiluted culture cells onto a surface area until cell clumps are visualized and then, upon cell clumping, moving the cells into a suspension culture system.
    Type: Grant
    Filed: July 1, 2013
    Date of Patent: March 24, 2015
    Assignee: Expression Therapeutics, LLC
    Inventors: Gabriela D. C. Denning, Richard E Gautney
  • High yield suspension cell line, system and method for making same
    Publication number: 20140011273
    Abstract: A system and method of adapting host cells to suspension cell culture and suspension cell lines ATCC PTA-12593 and ATCC PTA-12461 produced thereby are disclosed. The method includes the serial replating of substantially undiluted culture cells onto a surface area until cell clumps are visualized and then, upon cell clumping, moving the cells into a suspension culture system.
    Type: Application
    Filed: July 1, 2013
    Publication date: January 9, 2014
    Inventors: Gabriela D.C. Denning, Richard E. Gautney
  • High yield suspension cell line, system, and method for making same
    Publication number: 20120171724
    Abstract: A system and method of adapting host cells to suspension cell culture and a suspension cell line produced thereby are disclosed. The method includes the serial replating of substantially undiluted culture cells onto a surface area until cell clumps are visualized and then, upon cell clumping, moving the cells into a suspension culture system.
    Type: Application
    Filed: January 5, 2012
    Publication date: July 5, 2012
    Inventors: Gabriela D.C. Denning, Richard E. Gautney