Patents by Inventor Gabriella Rudy

Gabriella Rudy has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • PRECISE TEMPLATE-FREE CORRECTION OF BRCA1 MUTATION IN HUMAN CELLS VIA GENOME EDITING
    Publication number: 20230069642
    Abstract: Provided are compositions and methods used for precise template-free correction of BRCA1 mutation in human cells via genome editing. The method involves modifying DNA that includes a BRCA1-5382-InsC mutation by introducing into cells comprising the BRCA1-5382-InsC a Cas enzyme and a guide RNA. A guide RNA that produces improved results relative to other guide RNAs is provided. Also provided are modified stem cells that contain an introduced BRCA1-5382-InsC mutation.
    Type: Application
    Filed: August 12, 2022
    Publication date: March 2, 2023
    Inventors: Chengzu Long, Orrin Devinsky, Gabriella Rudy