Abstract: A method for reducing post-operative scar formation on a skin of a patient comprises applying a composition or material comprising copper, zinc and/or silver compounds to a postoperative wound under continuous peripheral pressure to the surgical incision and surrounding inflamed tissue, in order to reduce the inflammatory response, improve wound healing, reduce wounds complications and improve scar formation.

Abstract: A manufacturing method described in the present invention provides antimicrobial copper-containing polyurethane foams by embedding microparticles of metallic copper (Cu), cuprous oxide (Cu2O), cupric oxide (CuO), or cuprous iodide (CuI), or combinations thereof, into polyurethane foams, wherein said microparticles are homogenously distributed throughout the formed polymeric matrix of said foam. The method combines these copper-containing microparticles, or polyurethane liquid additive containing these particles, mixed in polyol with isocyanate.

Abstract: The present application relates to a method for reduction and prevention of damaged skin stasis comprising applying a material containing water-soluble or water-insoluble copper compounds to said damaged skin.

Abstract: The present invention relates to modified oligonucleotide therapeutic agents to selectively prevent gene transcription and expression in a sequence-specific manner. In particular, this invention relates to the selective inhibition of protein biosynthesis via antisense strategy using oligonucleotides constructed from arabinonucleotide or modified arabinonucleotide residues. More particularly this invention relates to the use of antisense oligonucleotides having arabinose sugars to hybridize to complementary RNA such as cellular messenger RNA, viral RNA, etc.

Abstract: Novel amino-modified polysaccharides are provided. The amino-modified polysaccharides have one or more amino groups, each being linked to one or more arginine residues.

Abstract: Novel conjugates composed of a saccharide-containing moiety (e.g., aminoglycosides) covalently linked to a moiety containing two or more basic amino acid residues (e.g., a polyarginine) and processes of preparing same are disclosed. Further disclosed are pharmaceutical compositions containing these conjugates and uses of these conjugates as antiviral and antibacterial agents.

Abstract: A pharmaceutical composition is provided. The pharmaceutical composition comprises an amino-modified polysaccharide having at least one amino group linked to a peptide composed of at least two basic amino acid residues.

Abstract: Method for preventing or inhibiting the transmission of HIV to susceptible uninfected cells by administering to the HIV, to cells infected with HIV, and/or to the uninfected cells, an effective amount of a compound of formula (I), wherein X is O or S, prior to the HIV or the cells infected with HIV, contacting the uninfected cells.