Patents by Inventor Galith Abourbeh

Galith Abourbeh has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Molecular imaging agents
    Patent number: 9205156
    Abstract: Provided is radiolabeled ammonium salts and uses thereof as myocardial perfusion agents in molecular imaging.
    Type: Grant
    Filed: May 26, 2011
    Date of Patent: December 8, 2015
    Assignee: HADASIT MEDICAL RESEARCH SERVICES & DEVELOPMENT LIMITED
    Inventors: Eyal Mishani, Ohad Ilovich, Hana Billauer, Sharon Dotan, Haim Danenberg, Moshe Bocher, Galith Abourbeh, Nanette Freedman
  • Polyalkylene glycol derivatives of inhibitors of epidermal growth factor receptor tyrosine kinase
    Patent number: 8461166
    Abstract: Novel epidermal growth factor receptor tyrosine kinase (EGFR-TK) inhibitors, pharmaceutical compositions including same and their use in the treatment of EGFR-TK related diseases or disorders are disclosed. Novel radiolabeled EGFR-TK inhibitors as their use as biomarkers for medicinal radioimaging such as Positron Emission Tomography (PET) and Single Photon Emission Computed Tomography (SPECT) and as radiopharmaceuticals for radiotherapy are further disclosed. The disclosed EGFR-TK inhibitors comprise a polyalkylene glycol moiety and/or a hydroxy-containing moiety and are characterized by improved solubility, biostability and bioavailability. Processes of preparing the disclosed EGFR-TK inhibitors and of radiolabeling same, via, for example, one-step radiosyntheses, are also disclosed.
    Type: Grant
    Filed: March 7, 2007
    Date of Patent: June 11, 2013
    Assignees: Hadasit Medical Research Services and Development Ltd., Yissum Research Development Company of the Hebrew University of Jerusalem Ltd.
    Inventors: Eyal Mishani, Samar Dissoki, Galith Abourbeh, Alexander Levitzki
  • MOLECULAR IMAGING AGENTS
    Publication number: 20110293519
    Abstract: Provided is radiolabeled ammonium salts and uses thereof as myocardial perfusion agents in molecular imaging.
    Type: Application
    Filed: May 26, 2011
    Publication date: December 1, 2011
    Applicant: HADASIT MEDICAL RESEARCH SERVICES & DEVELOPMENT LIMITED
    Inventors: Eyal MISHANI, Ohad ILOVICH, Hana BILLAUER, Sharon DOTAN, Haim DANENBERG, Moshe BOCHER, Galith ABOURBEH, Nanette FREEDMAN
  • Polyalkylene glycol derivatives of inhibitors of epidermal growth factor receptor tyrosine kinase
    Publication number: 20080056990
    Abstract: Novel epidermal growth factor receptor tyrosine kinase (EGFR-TK) inhibitors, pharmaceutical compositions including same and their use in the treatment of EGFR-TK related diseases or disorders are disclosed. Novel radiolabeled EGFR-TK inhibitors as their use as biomarkers for medicinal radioimaging such as Positron Emission Tomography (PET) and Single Photon Emission Computed Tomography (SPECT) and as radiopharmaceuticals for radiotherapy are further disclosed. The disclosed EGFR-TK inhibitors comprise a polyalkylene glycol moiety and/or a hydroxy-containing moiety and are characterized by improved solubility, biostability and bioavailability. Processes of preparing the disclosed EGFR-TK inhibitors and of radiolabeling same, via, for example, one-step radiosyntheses, are also disclosed.
    Type: Application
    Filed: March 7, 2007
    Publication date: March 6, 2008
    Applicant: T.K. Signal Ltd.
    Inventors: Eyal Mishani, Samar Dissoki, Galith Abourbeh, Alexander Levitzki
  • Novel irreversible inhibitors of epidermal growth factor receptor tyrosine kinase and uses thereof for therapy and diagnosis
    Publication number: 20060025430
    Abstract: Novel epidermal growth factor receptor tyrosine kinase (EGFR-TK) irreversible inhibitors, pharmaceutical compositions including same and their use in the treatment of EGFR-TK related diseases or disorders are disclosed. Novel radiolabeled EGFR-TK irreversible inhibitors as their use as biomarkers for medicinal radioimaging such as Positron Emission Tomography (PET) and Single Photon Emission Computed Tomography (SPECT) and as radiopharmaceuticals for radiotherapy are further disclosed.
    Type: Application
    Filed: July 21, 2005
    Publication date: February 2, 2006
    Inventors: Eyal Mishani, Yulia Rozen, Galith Abourbeh, Alexander Levitzki