Patents by Inventor Garrett Collins Heffner

Garrett Collins Heffner has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 11834668
    Abstract: The present invention provides methods and compositions for improving efficacy of viral transduction of cells. More particularly, the present invention provides methods and materials useful for safely and reliably improving the efficiency of methods and materials useful for safely and reliably improving the efficiency of methods for transducing cells, such as human hematopoietic stem cells (HSC), with viruses and/or viral vectors. The compositions and methods are useful for therapeutic indications amenable to treatment with hematopoietic stem cell gene therapies.
    Type: Grant
    Filed: December 17, 2020
    Date of Patent: December 5, 2023
    Assignee: bluebird bio, Inc.
    Inventors: Garrett Collins Heffner, Abraham Isaac Bassan
  • Publication number: 20210171980
    Abstract: The present invention provides methods and compositions for improving efficacy of viral transduction of cells. More particularly, the present invention provides methods and materials useful for safely and reliably improving the efficiency of methods and materials useful for safely and reliably improving the efficiency of methods for transducing cells, such as human hematopoietic stem cells (HSC), with viruses and/or viral vectors. The compositions and methods are useful for therapeutic indications amenable to treatment with hematopoietic stem cell gene therapies.
    Type: Application
    Filed: December 17, 2020
    Publication date: June 10, 2021
    Inventors: Garrett Collins Heffner, Abraham Isaac Bassan
  • Patent number: 10907177
    Abstract: The present invention provides methods and compositions for improving efficacy of viral transduction of cells. More particularly, the present invention provides methods and materials useful for safely and reliably improving the efficiency of methods and materials useful for safely and reliably improving the efficiency of methods for transducing cells, such as human hematopoietic stem cells (HSC), with viruses and/or viral vectors. The compositions and methods are useful for therapeutic indications amenable to treatment with hematopoietic stem cell gene therapies.
    Type: Grant
    Filed: October 28, 2019
    Date of Patent: February 2, 2021
    Assignee: bluebird bio, Inc.
    Inventors: Garrett Collins Heffner, Abraham Isaac Bassan
  • Publication number: 20200048657
    Abstract: The present invention provides methods and compositions for improving efficacy of viral transduction of cells. More particularly, the present invention provides methods and materials useful for safely and reliably improving the efficiency of methods and materials useful for safely and reliably improving the efficiency of methods for transducing cells, such as human hematopoietic stem cells (HSC), with viruses and/or viral vectors. The compositions and methods are useful for therapeutic indications amenable to treatment with hematopoietic stem cell gene therapies.
    Type: Application
    Filed: October 28, 2019
    Publication date: February 13, 2020
    Inventors: Garrett Collins Heffner, Abraham Isaac Bassan
  • Patent number: 10501759
    Abstract: The present invention provides methods and compositions for improving the efficacy of viral transduction of cells. More particularly, the present invention provides methods and materials useful for safely and reliably improving the efficiency of methods for transducing cells, such as human hematopoietic stem cells (HSC), with viruses and/or viral vectors. The compositions and methods are useful for therapeutic indications amenable to treatment with hematopoietic stem cell gene therapies.
    Type: Grant
    Filed: June 4, 2018
    Date of Patent: December 10, 2019
    Assignee: BLUEBIRD BIO, INC.
    Inventors: Garrett Collins Heffner, Abraham Isaac Bassan
  • Publication number: 20180363004
    Abstract: The present invention provides methods and compositions for improving the efficacy of viral transduction of cells. More particularly, the present invention provides methods and materials useful for safely and reliably improving the efficiency of methods for transducing cells, such as human hematopoietic stern cells (HSC), with viruses and/or viral vectors. The compositions and methods are useful for therapeutic indications amenable to treatment with hematopoietic stem cell gene therapies.
    Type: Application
    Filed: June 4, 2018
    Publication date: December 20, 2018
    Inventors: Garrett Collins Heffner, Abraham Isaac Bassan
  • Patent number: 9988644
    Abstract: The present invention provides methods and compositions for improving the efficacy of viral transduction of cells. More particularly, the present invention provides methods and materials useful for safely and reliably improving the efficiency of methods for transducing cells, such as human hematopoietic stem cells (HSC), with viruses and/or viral vectors. The compositions and methods are useful for therapeutic indications amenable to treatment with hematopoietic stem cell gene therapies.
    Type: Grant
    Filed: September 28, 2012
    Date of Patent: June 5, 2018
    Assignee: bluebird bio, Inc.
    Inventors: Garrett Collins Heffner, Abraham Isaac Bassan
  • Publication number: 20150216903
    Abstract: The present invention provides methods and compositions for improving the efficacy of gene delivery such as viral transduction of cells. More particularly, the present invention provides methods and materials useful for safely and reliably improving the efficiency of methods for transducing cells, such as human hematopoietic stem cells (HSC), with viruses and/or viral vectors. The compositions and methods are useful for therapeutic indications amenable to treatment with hematopoietic stem cell gene therapies. The present invention also provides methods and compositions for improving cell therapy and gene therapy.
    Type: Application
    Filed: August 9, 2013
    Publication date: August 6, 2015
    Applicant: BLUEBIRD BIO, INC.
    Inventors: Garrett Collins Heffner, Abraham Issac Bassan
  • Publication number: 20140234278
    Abstract: The present invention provides methods and compositions for improving the efficacy of viral transduction of cells. More particularly, the present invention provides methods and materials useful for safely and reliably improving the efficiency of methods for transducing cells, such as human hematopoietic stem cells (HSC), with viruses and/or viral vectors. The compositions and methods are useful for therapeutic indications amenable to treatment with hematopoietic stem cell gene therapies.
    Type: Application
    Filed: September 28, 2012
    Publication date: August 21, 2014
    Inventors: Garrett Collins Heffner, Abraham Issac Bassan