Patents by Inventor Garry J. Southan

Garry J. Southan has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Mercapto and seleno derivatives as inhibitors of nitric oxide synthase
    Patent number: 5985917
    Abstract: This invention is directed to a pharmacologically acceptable composition for inhibiting nitric oxide synthase in a mammal, which includes a mercapto or seleno derivative and a pharmaceutically acceptable carrier. The invention also concerns a method of inhibiting nitric oxide synthase, selectively inhibiting the inducible isoform of nitric oxide synthase, and treating various conditions where there is an advantage in inhibiting nitric oxide biosynthesis. The method includes the step of administering to a mammal a mercapto or seleno derivative in pure form or in a pharmaceutically acceptable carrier.
    Type: Grant
    Filed: March 29, 1999
    Date of Patent: November 16, 1999
    Assignee: Children's Hospital Medical Center
    Inventors: Garry J. Southan, Andrew L. Salzman, Csaba Szabo
  • Mercapto derivatives as inhibitors of nitric oxide synthase
    Patent number: 5952385
    Abstract: This invention is directed to a pharmacologically acceptable composition for inhibiting nitric oxide synthase in a mammal, which includes a mercapto derivative and a pharmaceutically acceptable carrier. The invention also concerns a method of inhibiting nitric oxide synthase, selectively inhibiting the inducible isoform of nitric oxide synthase, and treating various conditions where there is an advantage in inhibiting nitric oxide biosynthesis. The method includes the step of administering to a mammal a mercapto derivative in pure form or in a pharmaceutically acceptable carrier.
    Type: Grant
    Filed: July 8, 1997
    Date of Patent: September 14, 1999
    Assignee: Children's Hospital Medical Center
    Inventors: Garry J. Southan, Andrew L. Salzman, Csaba Szabo
  • Mercapto and seleno derivatives as inhibitors of nitric oxide synthase
    Patent number: 5929063
    Abstract: This invention is directed to a pharmacologically acceptable composition for inhibiting nitric oxide synthase in a mammal, which includes a mercapto or seleno derivative and a pharmaceutically acceptable carrier. The invention also concerns a method of inhibiting nitric oxide synthase, selectively inhibiting the inducible isoform of nitric oxide synthase, and treating various conditions where there is an advantage in inhibiting nitric oxide biosynthesis. The method includes the step of administering to a mammal a mercapto or seleno derivative in pure form or in a pharmaceutically acceptable carrier.
    Type: Grant
    Filed: October 20, 1995
    Date of Patent: July 27, 1999
    Assignee: Children's Hospital Medical Center
    Inventors: Garry J. Southan, Andrew L. Salzman, Csaba Szabo
  • Mercapto derivatives as inhibitors of nitric oxide synthase
    Patent number: 5674907
    Abstract: This invention is directed to a pharmacologically acceptable composition for inhibiting nitric oxide synthase in a mammal, which includes a mercapto derivative and a pharmaceutically acceptable carrier. The invention also concerns a method of inhibiting nitric oxide synthase, selectively inhibiting the inducible isoform of nitric oxide synthase, and treating various conditions where there is an advantage in inhibiting nitric oxide biosynthesis. The method includes the step of administering to a mammal a mercapto derivative in pure form or in a pharmaceutically acceptable carrier.
    Type: Grant
    Filed: March 24, 1995
    Date of Patent: October 7, 1997
    Assignee: Children's Hospital Medical Center
    Inventors: Garry J. Southan, Andrew L. Salzman, Csaba Szabo