Patents by Inventor Gary C. Smith, Jr.

Gary C. Smith, Jr. has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Treating sickle cell disease with a pyruvate kinase R activating compound
    Patent number: 11980611
    Abstract: Compounds that activate pyruvate kinase R can be used for the treatment of sickle cell disease (SCD). Methods and compositions for the treatment of SCD are provided herein, including a therapeutic compound designated as Compound 1.
    Type: Grant
    Filed: December 22, 2022
    Date of Patent: May 14, 2024
    Assignee: Novo Nordisk Health Care AG
    Inventors: Anna Ericsson, Neal Green, Gary Gustafson, Bingsong Han, David R. Lancia, Jr., Lorna Mitchell, David Richard, Tatiana Shelekhin, Chase C. Smith, Zhongguo Wang, Xiaozhang Zheng
  • PYRROLOPYRROLE COMPOSITIONS AS PYRUVATE KINASE (PKR) ACTIVATORS
    Publication number: 20240083901
    Abstract: The disclosure relates to modulating pyruvate kinase and provides novel chemical compounds useful as activators of PKR, as well as various uses of these compounds. PKR activating compounds are useful in the treatment of diseases and disorders associated with PKR and/or PKM2, such as pyruvate kinase deficiency (PKD), sickle cell disease (SCD), and thalassemia.
    Type: Application
    Filed: March 21, 2023
    Publication date: March 14, 2024
    Inventors: Anna ERICSSON, Neal GREEN, Gary GUSTAFSON, Bingsong HAN, David R. LANCIA, JR., Lorna MITCHELL, David RICHARD, Tatiana SHELEKHIN, Chase C. SMITH, Zhongguo WANG, Xiaozhang ZHENG
  • Paint pump for airless spray guns
    Patent number: 4030857
    Abstract: This invention relates to a fluid actuated paint pump for high pressure airless spray guns and includes a novel unloading system in combination with a self-reversing fluid motor connected to a double-acting pump which supplies paint from a reservoir to an airless spray gun at a pressure which may run as high as 3500 psi.
    Type: Grant
    Filed: October 29, 1975
    Date of Patent: June 21, 1977
    Assignee: Champion Spark Plug Company
    Inventor: Gary C. Smith, Jr.