Abstract: An apparatus and method for mixing parenteral nutrition solutions from additives in a plurality of vials containing the additives, in which a vented spike is inserted through a disposable rack and into the stoppered end of each vial, with the vials secured on the rack. The rack is engaged on a stand through a quick release fitting, and maintains the vials in a vertical orientation with the labels clearly visible. A dedicated syringe is connected with each vial in aligned relationship therewith through a unique two-way valve which is mounted to a manifold. In one form of the invention, the valve is attached directly on the manifold to reduce dead space volume and consequently reduce residual fluid in the system between purges. A flushing system is attached to one end of the manifold to flush any residual fluids into the final container at the end of a transfer process.

Abstract: A tamper-resistant filled syringe protective capping device which comprises a one-piece molded product, comprising a base section having a portion thereof provided with a female luer port, a sterility protector, and two side portions which at their furthest ends are provided with complementary locking structure so that when a filled syringe is inserted into the luer port at the base section of the unit, the two side portions can be folded therearound and locked into position to form a tamper-evident container for maintaining a filled syringe in tamper-proof condition.