Abstract: A desktop-type ventilation system generally includes a ventilation hub having at least one vent and at least one fume hood connected thereto. The fume hood(s) generally include a pair of side walls, wherein each is disposed at an angle for directing and causing air to be funneled toward the vent. The fume hood(s) include a front wall defining an inlet orifice, a rear wall having an outlet orifice for connection to the vent, and a top wall disposed at an angle of elevation from the rear wall to the front wall. The front wall is detachably securable to the side walls and the top wall such that the fume hood(s) may be broken down after use and nested for storage. The ventilation hub may detachably secure to a work surface such that it may be removed therefrom and conveniently stored when not in use.