Abstract: A panel system includes a chassis holding one or more tray arrangements, which are each configured to receive one or more cassettes at two or more bays. The tray arrangements and cassettes cooperate to define a cassette sensor arrangement and a port occupancy sensor arrangement having separate interface points. The cassette sensor arrangement may include electronic memory storing physical layer information about the cassette. All active components of the port occupancy sensor arrangement are disposed on the tray while the electronic memories of the cassette sensor arrangement are stored on the cassettes.

Abstract: Provided herein are methods of treating a subject, such as a subject that has cancer, that include administering a therapeutically effective amount of a STING antagonist or a pharmaceutically acceptable salt, solvate, or co-crystal thereof to a subject identified as having: (I) a cancer cell having one or both of (i) decreased TREX1 level and/or activity, and (ii) increased cGAS/STING signaling pathway activity, e.g., as compared to a reference level, and/or (II) an elevated level of cGAMP in a serum or tumor sample obtained from the subject, e.g., as compared to a reference level.

Abstract: Provided herein are methods of treating a subject, such as a subject that has cancer, that include administering a therapeutically effective amount of a STING antagonist or a cGAS inhibitor or a pharmaceutically acceptable salt, solvate, or co-crystal thereof to a subject identified as having decreased SMARCB1 level and/or activity in a tumor sample obtained from the subject as compared to a reference level.

Abstract: Described are substrate containers that are useful for holding or transporting substrates such as semiconductor wafers and microelectronic devices, in a clean environment, as well as methods of using the substrate containers.

Abstract: Various shaped abrasive particles are disclosed. Each shaped abrasive particle includes a body having at least one major surface and a side surface extending from the major surface.

Abstract: This disclosure features chemical entities (e.g., a compound or a pharmaceutically acceptable salt, and/or hydrate, and/or cocrystal, and/or drug combination of the compound) that inhibit (e.g., antagonize) Stimulator of Interferon Genes (STING). Said chemical entities are useful, e.g., for treating a condition, disease or disorder in which increased (e.g., excessive) STING activation (e.g., STING signaling) contributes to the pathology and/or symptoms and/or progression of the condition, disease or disorder (e.g., cancer) in a subject (e.g., a human). This disclosure also features compositions containing the same as well as methods of using and making the same.

Abstract: A system and method are provided for operating a pool of workers within a distributed computing system, wherein each of multiple computers host one or more workers. Each computer also hosts ledgers for one or more originators of tasks that are submitted to the pool for processing. A ledger identifies tasks from the corresponding originator that have been submitted to the pool and that have not yet been completed. When an originator submits a new task, the system (e.g., a coordinator) identifies a maximum number of concurrent tasks permitted the originator and determines, with reference to the originator's ledger, whether the task can be submitted to the pool without exceeding the limit. If so, the task is assigned to an idle worker (if any) and is added to the originator's ledger. After completion, the task is removed from the ledger. Obsolete or stale entries are periodically purged from originators' ledgers.

Abstract: The present invention relates to systems and methods for finding and sampling hydrocarbons from seeps in water or from artificial sources of water. The present invention related to systems and methods for in situ analyzing fluid samples in a body of water. The systems and methods can be used to find hydrocarbons and associated non-hydrocarbons from seeps in water. Such seeps may come from natural sources in deep water, possibly as deep as 3000 m or even more.

Abstract: A non-linear dynamic process such as multiphase flow is characterized to determine a condition of the process. A sensor may obtain information about strain, vibration, flow rate, etc. during the process. That sensor data may be plotted, and at least one perceptual hash can be generated from the plot. The perceptual hash can be compared against a database storing plots or hashes for non-linear dynamic responses for different sensor types or processes. A best fit hash may be identified and used to determine what conditions are occurring in the field, or multiple near fits can define an envelope of experimental/reference conditions with similar non-linear dynamics to the field system. Multiple hash comparisons may be used to refine the envelope, determine a best fit, or determine what measurement would help discriminate the flow conditions.

Abstract: A rim strike assembly includes a strike body, strike jaw, retaining clutch, locking cam, locking clutch, and a solenoid. The strike jaw, retaining clutch, locking cam, and locking clutch are pivotably coupled to the strike body. The strike body and strike jaw define a latch cavity to receive a latch of a door. The strike jaw includes a jaw follower. The strike jaw is pivotable between a release position and a closed position. The retaining clutch engages the jaw follower and includes a retaining follower. The locking cam includes a retaining notch and a locking notch. The retaining follower engages the retaining notch. The locking clutch includes a locking follower that engages the locking notch of the locking cam. The solenoid includes a plunger coupled to the locking clutch such that movement of the plunger rotates the locking clutch from a locked position to an unlocked position.

Abstract: A system and method of providing wagering over a computerized system. The system includes a computerized multi-player game. The game includes an integral game mechanics module for providing a game-play session over a computerized network. The game mechanics module is in real-time communication with a wagering module and therethrough the wagering module automatically receiving real-time game event information. The game mechanics module provides a wagering option to a player in real-time that is selectable by a game-play action.

Abstract: Torque sensing devices, systems, and methods are capable of measuring and/or determining a torque being transmitted through a shaft by measuring the torsional deformation of the shaft over a short length thereof. Such devices, systems, and devices have a sensor positioned adjacent to the outer surface of the shaft as it rotates, the sensor being positioned to maintain a substantially constant distance between the sensor and the outer surface of the shaft. The sensors may be variable reluctance (VR) sensors rigidly attached to a frame mounted on a bearing (e.g., a hanger bearing), which is mounted on the shaft, such that relative radial motion between the shaft and the VR sensor is minimized (e.g., so that they move in unison). Reducing this amount of motion results in a more accurate torque measurement.

Abstract: The present invention relates to systems and methods for finding and sampling hydrocarbons from seeps in water or from artificial sources of water. The present invention related to systems and methods for in situ analyzing fluid samples in a body of water. The systems and methods can be used to find hydrocarbons and associated non-hydrocarbons from seeps in water. Such seeps may come from natural sources in deep water, possibly as deep as 3000 m or even more.

Abstract: A system and method for controlling a vehicle (100), the vehicle (100) having an autonomous mode of operation, the system comprising: one or more sensors (102) configured to measure one or more parameters associated with an operator (110) controlling the vehicle (100) to perform a first operation; and one or more processors (106) configured to: determine that measurements taken by the one or more sensors (102) fulfil one or more predetermined criteria; responsive to determining that the measurements taken by the one or more sensors (102) fulfil the one or more predetermined criteria, determine a second operation for performance by the vehicle (100); and control the vehicle (100) in the autonomous mode such that the vehicle (100) performs the second operation.

Abstract: The present design includes eyewear including an eyewear chassis comprising two openings and receiving elements formed in the eyewear chassis, the receiving elements firmly and securely receiving a rotatable element connectable to a facia plate maintaining a removable pair of lenses. In some embodiments, rotating the removable pair of lenses from a fully closed position away from the eyewear chassis causes the facia plate to receive upward force to raise the removable pair of lenses to a fully open position, and from the fully open position toward the eyewear chassis causes the facia plate to receive downward force to lower the removable pair of lenses to the fully closed position. One lens of the removable pair of lenses in an embodiment fits within at least one milled recessed inner edge formed within one of the two openings when the removable pair of lenses is in the fully closed position.

Abstract: A computerized authorization system configured to authorize electronically-made requests to an electronic entity. The computerized authorization system comprises a store configured to store an indication of at least one predetermined electronic authorization device configured to authorize each electronically-made request. The computerized authorization system is further configured such that: in response to receiving an electronically-made request to the electronic entity, an indication of the request is output to the at least one predetermined electronic authorization device configured to authorize the request as indicated in the store; and in response to receiving an indication of authorization from the at least one predetermined electronic authorization device, an indication of authorization of the request is output to the electronic entity.

Abstract: A rim strike assembly includes a strike body, strike jaw, retaining clutch, locking cam, locking clutch, and a solenoid. The strike jaw, retaining clutch, locking cam, and locking clutch are pivotably coupled to the strike body. The strike body and strike jaw define a latch cavity to receive a latch of a door. The strike jaw includes a jaw follower. The strike jaw is pivotable between a release position and a closed position. The retaining clutch engages the jaw follower and includes a retaining follower. The locking cam includes a retaining notch and a locking notch. The retaining follower engages the retaining notch. The locking clutch includes a locking follower that engages the locking notch of the locking cam. The solenoid includes a plunger coupled to the locking clutch such that movement of the plunger rotates the locking clutch from a locked position to an unlocked position.

Abstract: Example aspects of a layered assembly for a reflective product and a method for forming a layered assembly for a reflective product are disclosed. The layered assembly for a reflective product can comprise a substrate layer; a reflective laminate layer adhered to the substrate layer; an ink layer printed on the reflective laminate layer; and, in some implementations, a protective laminate layer adhered to the ink layer.

Abstract: Luminescent compositions are provided having improved color intensity and articles incorporating said luminescent compositions as security taggants, for example as anti-counterfeiting components in pharmaceutical packaging applications, or as aesthetic colorants that are generally usable in any application where luminescent coloration is desired. The luminescent compositions incorporate a particulate fluoropolymer that is blended with one or more luminescent pigments and/or luminescent dyes. These components are provided in a liquid medium in which the fluoropolymer particles are dispersed and with which the pigment(s)/dye(s) may or may not be soluble.

Abstract: A rim strike assembly includes a strike body, strike jaw, retaining clutch, locking cam, locking clutch, and a solenoid. The strike jaw, retaining clutch, locking cam, and locking clutch are pivotably coupled to the strike body. The strike body and strike jaw define a latch cavity to receive a latch of a door. The strike jaw includes a jaw follower. The strike jaw is pivotable between a release position and a closed position. The retaining clutch engages the jaw follower and includes a retaining follower. The locking cam includes a retaining notch and a locking notch. The retaining follower engages the retaining notch. The locking clutch includes a locking follower that engages the locking notch of the locking cam. The solenoid includes a plunger coupled to the locking clutch such that movement of the plunger rotates the locking clutch from a locked position to an unlocked position.