Patents by Inventor Gary Robert Kelm
Gary Robert Kelm has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20230381102Abstract: The present application relates to a rinse-off composition comprising an oil phase and an aqueous surfactant matrix, wherein one or more active agents are dissolved in one or more non-polar, water-immiscible solvents, and the oil phase is dispersed in the aqueous surfactant matrix. The present application also relates to methods of delivering the active agent(s) to a subject in need thereof topically, for example to the skin, the hair, and scalp. The present application also relates to use of the rinse-off compositions to treat and/or prevent topical conditions such as dermatitis and psoriasis. In some embodiments, the rinse-off compositions of the present application are shampoo compositions.Type: ApplicationFiled: August 3, 2023Publication date: November 30, 2023Applicant: CRESCITA THERAPEUTICS INC.Inventors: Gary Robert KELM, Wade HULL, Carolyn Shawn MURPHY
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Publication number: 20230355898Abstract: An antiviral medication which may be an aerosolizable formulation having a pharmaceutically active anti-viral compound present as a neutral compound selected from the group of free acid, free base, water insoluble salt and water insoluble ion pair); an excipient capable of forming a liquid complex with the pharmaceutically active anti-viral compound; and a polymeric surfactant suitable for pulmonary administration. A nebulizer to deliver the antiviral medication may have a compressed air chamber in communication with a medication chamber, the communication sealed by a spring valve in a rested state. A nebulizer chamber is in communication with the medication chamber, the nebulizer chamber having a pressure release orifice to deliver a stream the nebulized particle stream to the facemask and a continuously variable nebulizing pressure feed at the pressure release orifice.Type: ApplicationFiled: September 21, 2021Publication date: November 9, 2023Inventors: Andrey FACTOR, Gary Robert KELM, Edward Ronald GRIFFOR, Donald O. KING
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Publication number: 20210169800Abstract: The present application relates to a rinse-off composition comprising an oil phase and an aqueous surfactant matrix, wherein one or more active agents are dissolved in one or more non-polar, water-immiscible solvents, and the oil phase is dispersed in the aqueous surfactant matrix. The present application also relates to methods of delivering the active agent(s) to a subject in need thereof topically, for example to the skin, the hair, and scalp. The present application also relates to use of the rinse-off compositions to treat and/or prevent topical conditions such as dermatitis and psoriasis. In some embodiments, the rinse-off compositions of the present application are shampoo compositions.Type: ApplicationFiled: February 5, 2021Publication date: June 10, 2021Applicant: CRESCITA THERAPEUTICS INC.Inventors: Gary Robert KELM, Wade HULL, Carolyn Shawn MURPHY
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Patent number: 10945952Abstract: The present application relates to a rinse-off composition comprising an oil phase and an aqueous surfactant matrix, wherein one or more active agents are dissolved in one or more non-polar, water-immiscible solvents, and the oil phase is dispersed in the aqueous surfactant matrix. The present application also relates to methods of delivering the active agent(s) to a subject in need thereof topically, for example to the skin, the hair, and scalp. The present application also relates to use of the rinse-off compositions to treat and/or prevent topical conditions such as dermatitis and psoriasis. In some embodiments, the rinse-off compositions of the present application are shampoo compositions.Type: GrantFiled: March 16, 2020Date of Patent: March 16, 2021Assignee: CRESCITA THERAPEUTICS INC.Inventors: Gary Robert Kelm, Wade Hull, Carolyn Shawn Murphy
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Publication number: 20200289415Abstract: The present application relates to a rinse-off composition comprising an oil phase and an aqueous surfactant matrix, wherein one or more active agents are dissolved in one or more non-polar, water-immiscible solvents, and the oil phase is dispersed in the aqueous surfactant matrix. The present application also relates to methods of delivering the active agent(s) to a subject in need thereof topically, for example to the skin, the hair, and scalp. The present application also relates to use of the rinse-off compositions to treat and/or prevent topical conditions such as dermatitis and psoriasis. In some embodiments, the rinse-off compositions of the present application are shampoo compositions.Type: ApplicationFiled: March 16, 2020Publication date: September 17, 2020Applicant: CRESCITA THERAPEUTICS INC.Inventors: Gary Robert KELM, Wade HULL, Carolyn Shawn MURPHY
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Patent number: 8372430Abstract: Disclosed are compositions, methods, and kits for treating conditions including; ameliorating side effects associated with compounds such as lipase inhibitors; gastrointestinal distress; fecal urgency; obesity; hyperlipidemia; diarrhea; reducing levels of toxic substances; reducing blood cholesterol levels; inducing satiety; effecting weight loss; effecting weight control; and treating, delaying onset and/or preventing Type II diabetes. One embodiment includes compositions for administration to an animal for stiffening lipophilic substances in the gastrointestinal tract. Such stiffening agents have a complete melting point of about 33° C. or greater. Kits comprising the composition are also included. Methods of stiffening lipophilic substances present in the gastrointestinal tract of an animal are also provided. The methods comprise administering a composition comprising a safe and effective amount of a stiffening agent to an animal.Type: GrantFiled: October 31, 2003Date of Patent: February 12, 2013Assignee: The Procter & Gamble CompanyInventors: Ronald James Jandacek, William Randall Francis, Gary Robert Kelm, Bryn Hird
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Patent number: 8287898Abstract: The present invention is for compositions and methods for managing the body weight of a subject using said compositions. Weight management, particularly weight gain and loss, is effectuated by producing a sensation of satiety in said subjects. The method of managing body weight includes administering the composition prior to food consumption, concurrent with food consumption, as replacement for food consumption and combinations thereof.Type: GrantFiled: May 3, 2005Date of Patent: October 16, 2012Assignee: The Procter & Gamble CompanyInventors: Ronald James Jandacek, Gary Robert Kelm, Satinder Singh Bharaj, Jorge Villanueva Penafiel
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Publication number: 20100305169Abstract: A personal-care composition in the form of an oil-in-water emulsion comprises a water phase, an oil phase, an anionic pairing agent, a cationic active, and an anionic thickener. In one embodiment, the anionic pairing agent is pre-formed from the neutralization of an acid with a base. In another embodiment, the anionic pairing agent is formed in situ from the neutralization of an acid with a base. At least 25% by weight of the cationic active is present in the oil phase. In certain embodiments, a method for regulating keratinous tissue condition and a method for improving deliverability of a cationic active in the presence of an anionic thickener comprise the steps of: providing the aforementioned personal-care composition, and applying the composition to keratinous tissue in need of treatment. The personal-care composition allows for previously unattainable levels of the cationic active to locate within the oil phase of the emulsion.Type: ApplicationFiled: March 23, 2010Publication date: December 2, 2010Inventors: Larry Rich Robinson, Gary Robert Kelm, Denver Michael Faulk
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Publication number: 20100305168Abstract: In one embodiment, a personal-care composition in the form of an oil-in-water emulsion comprises an anionic pairing agent, a cationic active, and an anionic thickener. In another embodiment, the anionic pairing agent is pre-formed from the neutralization of an acid with a base. In another embodiment, the anionic pairing agent is formed in situ from the neutralization of an acid with a base. In one embodiment, the molar ratio of the base to the acid is at least about 0.70. In another embodiment, the equivalent ratio of the anionic pairing agent to the cationic active is at least about 0.70. The personal-care composition allows for previously unattainable levels of the cationic active to locate within the oil phase of the emulsion.Type: ApplicationFiled: March 23, 2010Publication date: December 2, 2010Inventors: Larry Rich Robinson, Gary Robert Kelm, Denver Michael Faulk
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Patent number: 7025984Abstract: The present invention is for compositions and methods for managing the body weight of a subject using said compositions. Weight management, particularly weight gain and loss, is effectuated by producing a sensation of satiety in said subjects. The method of managing body weight includes administering the composition prior to food consumption, concurrent with food consumption, as replacement for food consumption and combinations thereof.Type: GrantFiled: June 26, 2000Date of Patent: April 11, 2006Assignee: The Procter & Gamble CompanyInventors: Ronald James Jandacek, Gary Robert Kelm, Satinder Singh Bharaj, Jorge Villanueva Penafiel
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Publication number: 20040126424Abstract: This disclosure relates to compositions suitable for a variety of treatments, including ameliorating the undesirable side effects associated with compounds such as lipase inhibitors (e.g., anal leakage of undigested fat or oil). In particular, one embodiment of the present invention relates to compositions that are suitable for administration to an animal for the purpose of stiffening one or more lipophilic substances present in the gastrointestinal tract of the animal. The stiffening agents have a complete melting point of about 33° C. or greater. Various kits comprising the compositions are also described herein.Type: ApplicationFiled: October 31, 2003Publication date: July 1, 2004Inventors: Ronald James Jandacek, William Randall Francis, Gary Robert Kelm, Bryn Hird
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Publication number: 20040044079Abstract: Disclosed herein are methods of promoting weight control in a companion animal comprising orally administering one or more non-glyceryl derivatives of C17 or greater fatty acids. Also disclosed are methods for promoting weight control in a human comprising orally administering non-glyceryl derivatives of C17 or greater fatty acids, wherein the fatty acid derivatives do not cause the human to reduce food consumption. Further disclosed are methods for promoting weight control in a human or companion animal comprising orally administering lotus leaf extract.Type: ApplicationFiled: September 3, 2003Publication date: March 4, 2004Applicant: The IAMS CompanyInventors: Gregory Dean Sunvold, Robert Jason Vickers, Gary Robert Kelm, Susan Liew Giovengo, Steven Trevor Meller
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Publication number: 20030203004Abstract: Described herein are compositions comprising short and long chain fatty acids which are suitable for oral administration, wherein the compositions are useful for the management of body weight. For example, as described, body weight management may be effected via induction of satiety, by using a composition of the present invention.Type: ApplicationFiled: August 7, 2002Publication date: October 30, 2003Inventors: Gary Robert Kelm, Jeffrey Warren Clymer, Satinder Singh Bharaj, Mary Ann Starcher, Cynthia Elodi Francis
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Publication number: 20030069618Abstract: The present invention concerns a method and a kit, for the treatment of a selected area of the skin and/or subcutaneous tissue, and in particular for the cosmetic treatment of skin conditions such as regional fat deposits including cellulite. The method comprises heating the selected area to a sustained skin temperature of about 32 to about 50° C. for a desired period of time, using a device comprising either a heat source capable of conductively heating the selected area or, alternatively, an infra-red source for emitting infra-red with a wavelength from about 700 nm to about 15000 nm.Type: ApplicationFiled: April 25, 2002Publication date: April 10, 2003Inventors: Edward Dewey Smith, John Erich Oblong, Jonathan Todd Samuel, Donald Lynn Bissett, Charles Carson Bascom, Gary Robert Kelm
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Patent number: 5914132Abstract: The present invention relates to a pharmaceutical composition in a unit dosage form for peroral administration in a human or lower animal, having a gastrointestinal tract comprising a small intestine and a colon with a lumen therethrough having an inlet to the colon from the small intestine, comprising:a. a safe and effective amount of a therapeutically active agent incorporated into a compressed, bi-convex tablet, with a maximum diameter of about 4 mm to about 10 mm;b. a non-pH dependent smoothing coat applied to the tablet to provide a smooth tablet surface free from edges or sharp curves; andc. an enteric polymer coating material comprising at least one inner coating layer and only one outer coating layer;wherein the therapeutically active agent is released at a point near the inlet to, or within the colon; each of the inner coating layer(s) is an enteric polymer that begins to dissolve in an aqueous media at a pH between about 5 to about 6.Type: GrantFiled: October 11, 1996Date of Patent: June 22, 1999Assignee: The Procter & Gamble CompanyInventors: Gary Robert Kelm, Koji Kondo, Akio Nakajima
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Patent number: 5843479Abstract: The present invention relates to a pharmaceutical composition in a unit dosage form for peroral administration in a human or lower animal, having a gastrointestinal tract comprising a small intestine and a colon with a lumen therethrough having an inlet to the colon from the small intestine, comprising:a. a safe and effective amount of rapidly dissolving bisacodyl incorporated into a compressed, bi-convex tablet, with a maximum diameter of about 4 mm to about 10 mm;b. a non-pH dependent smoothing coat applied to the tablet to provide a smooth tablet surface free from edges and sharp curves; andc. an enteric polymer coating material comprising at least one inner coating layer and only one outer coating layer;wherein the rapidly dissolving bisacodyl is released at a point near the inlet to, or within the colon; each of the inner coating layer(s) is an enteric polymer that begins to dissolve in an aqueous media at a pH between about 5 to about 6.Type: GrantFiled: October 11, 1996Date of Patent: December 1, 1998Assignee: The Procter & Gamble CompanyInventors: Gary Robert Kelm, Koji Kondo, Akio Nakajima
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Patent number: 5814336Abstract: The present invention relates to a pharmaceutical composition in a unit dosage form for peroral administration in a human or lower animal, having a gastrointestinal tract comprising a small intestine and a colon with a lumen therethrough having an inlet to the colon from the small intestine, comprising:a. a safe and effective amount of a therapeutically active agent incorporated into or coated on the surface of a dosage form selected from the group consisting of a spherical substrate, an elliptical substrate, a hard capsule, or a compressed tablet, with a maximum diameter of about 3 mm to about 10 mm; andb. an enteric polymer coating material;wherein the dosage form has a smooth surface free from edges or sharp curves; the elliptical substrate and the hard capsule have a ratio of the long to short diameters of no greater than about 1.Type: GrantFiled: September 24, 1996Date of Patent: September 29, 1998Assignee: The Procter & Gamble CompanyInventors: Gary Robert Kelm, Gary Lee Manring
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Patent number: 5785951Abstract: The present invention relates to methods and compositions for prevention or treatment of bone loss due to periodontal disease, oral osseous surgery, periodontal flap surgery, tooth extraction, dental implants, or scaling and root planing comprising topical administration, to mucosal tissues of the oral cavity, of a composition having from about 0.001% to about 0.2% ketorolac in the oral cavity.Type: GrantFiled: July 18, 1995Date of Patent: July 28, 1998Assignee: The Procter & Gamble CompanyInventors: Gary Robert Kelm, Harvey Marvin Pickrum, Matthew Joseph Doyle, William Buchanan
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Patent number: 5686105Abstract: The present invention relates to a pharmaceutical composition in a unit dosage form for peroral administration in a human or lower animal, having a gastrointestinal tract comprising a small intestine and a colon with a lumen therethrough having an inlet to the colon from the small intestine, comprising:a. a safe and effective amount of a therapeutically active agent incorporated into or coated on the surface of a dosage form selected from the group consisting of a spherical substrate, an elliptical substrate, a hard capsule, or a compressed tablet, with a maximum diameter of about 3 mm to about 10 mm; andb. an enteric polymer coating material comprising at least one inner coating layer and one outer coating layer;wherein the dosage form has a smooth surface free from edges or sharp curves; the elliptical substrate and the hard capsule have a ratio of the long to short diameters of no greater than about 1.Type: GrantFiled: May 17, 1995Date of Patent: November 11, 1997Assignee: The Procter & Gamble CompanyInventors: Gary Robert Kelm, Gary Lee Manring
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Patent number: 5686106Abstract: The present invention relates to a pharmaceutical composition in a unit dosage form for peroral administration in a human or lower animal, having a gastrointestinal tract comprising a small intestine and a colon with a lumen therethrough having an inlet to the colon from the small intestine, comprising:a. a safe and effective amount of a therapeutically active agent incorporated into or coated on the surface of a dosage form selected from the group consisting of a spherical substrate, an elliptical substrate, a hard capsule, or a compressed tablet, with a maximum diameter of about 3 mm to about 10 mm; andb. an enteric polymer coating material;wherein the dosage form has a smooth surface free from edges or sharp curves; the elliptical substrate and the hard capsule have a ratio of the long to short diameters of no greater than about 1.Type: GrantFiled: May 17, 1995Date of Patent: November 11, 1997Assignee: The Procter & Gamble CompanyInventors: Gary Robert Kelm, Gary Lee Manring