Patents by Inventor Gary S. Bartley

Gary S. Bartley has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • 17?-amino and hydroxylamino-11 ?-arylsteroids and their derivatives having agonist or antagonist hormonal properties
    Patent number: 7018991
    Abstract: The invention is directed to a novel class of steroids which exhibit potent antiprogestational activity.
    Type: Grant
    Filed: July 2, 2003
    Date of Patent: March 28, 2006
    Assignee: Research Triangle Institute
    Inventors: C. Edgar Cook, John A. Kepler, Gary S. Bartley, Rupa S. Shetty
  • 17 Beta-amino and hydroxylamino-11 beta-arylsteroids and their derivatives having agonist or antagonist hormonal properties
    Publication number: 20040023936
    Abstract: The invention is directed to a novel class of steroids which exhibit potent antiprogestational activity.
    Type: Application
    Filed: July 2, 2003
    Publication date: February 5, 2004
    Applicant: RESEARCHTRIANGLE INSTITUTE
    Inventors: C. Edgar Cook, John A. Kepler, Gary S. Bartley, Rupa S. Shetty
  • Taxane prodrugs
    Publication number: 20030203961
    Abstract: Taxane prodrugs comprise a taxane joined by a hydrolyzable bond to one or more oligomers that comprise a polyethylene glycol moiety. The oligomer preferably further comprises a salt-forming moiety.
    Type: Application
    Filed: March 24, 2003
    Publication date: October 30, 2003
    Inventors: Nnochiri N. Ekwuribe, Christopher H. Price, Gary S. Bartley
  • 17&bgr;-amino and hydroxylamino-11&bgr;-arylsteroids and their derivatives having agonist or antagonist hormonal properties
    Patent number: 6620801
    Abstract: The invention is directed to a novel class of steroids which exhibit potent antiprogestational activity.
    Type: Grant
    Filed: July 2, 2001
    Date of Patent: September 16, 2003
    Assignee: Research Triangle Institute
    Inventors: C. Edgar Cook, John A. Kepler, Gary S. Bartley, Rupa S. Shetty
  • Taxane prodrugs
    Patent number: 6541508
    Abstract: Taxane prodrugs comprise a taxane joined by a hydrolyzable bond to one or more oligomers that comprise a polyethylene glycol moiety. The oligomer preferably further comprises a salt-forming moiety.
    Type: Grant
    Filed: March 9, 2001
    Date of Patent: April 1, 2003
    Assignee: Nobex Corporation
    Inventors: Nnochiri N. Ekwuribe, Christopher H. Price, Gary S. Bartley
  • 17beta-amino and hydroxylamino-11beta-arylsteroids and their derivatives having agonist or antagonist hormonal properties
    Publication number: 20020065257
    Abstract: The invention is directed to a novel class of steroids which exhibit potent antiprogestational activity.
    Type: Application
    Filed: July 2, 2001
    Publication date: May 30, 2002
    Applicant: RESEARCH TRIANGLE INSTITUTE
    Inventors: C. Edgar Cook, John A. Kepler, Gary S. Bartley, Rupa S. Shetty
  • Taxane prodrugs
    Patent number: 6380405
    Abstract: The present invention generally provides taxane prodrugs comprising at least one taxane joined by hydrolyzable bond(s) to one or more polyethylene glycol oligomer(s) selected from the group consisting of a straight or branched polyethylene glycol oligomer having from 1 to 25 polyethylene glycol units and optionally comprising a salt-forming moiety. The polyethylene glycol oligomer preferably comprises a salt-forming moiety, which is preferably selected from the group consisting of ammonium and carboxylate.
    Type: Grant
    Filed: December 31, 1999
    Date of Patent: April 30, 2002
    Assignee: Nobex Corporation
    Inventors: Nnochiri Ekwuribe, Gary S. Bartley, Christopher H. Price
  • Taxane prodrugs
    Publication number: 20020013484
    Abstract: Taxane prodrugs comprise a taxane joined by a hydrolyzable bond to one or more oligomers that comprise a polyethylene glycol moiety. The oligomer preferably further comprises a salt-forming moiety.
    Type: Application
    Filed: March 9, 2001
    Publication date: January 31, 2002
    Inventors: Nnochiri N. Ekwuribe, Christopher H. Price, Gary S. Bartley
  • 17&bgr;-amino and hydroxylamino-11&bgr;-arylsteroids and their derivatives having agonist or antagonist hormonal properties
    Patent number: 6262042
    Abstract: The invention is directed to a novel class of steroids which exhibit potent antiprogestational activity.
    Type: Grant
    Filed: May 29, 1998
    Date of Patent: July 17, 2001
    Assignee: Research Triangle Institute
    Inventors: C. Edgar Cook, John A. Kepler, Gary S. Bartley
  • 17.beta.-nitro-11.beta.-arylsteroids and their derivatives having agonist or antagonist hormonal properties
    Patent number: 6093707
    Abstract: The invention is directed to a novel class of steroids which exhibit potent antiprogestational activity.
    Type: Grant
    Filed: November 5, 1999
    Date of Patent: July 25, 2000
    Assignee: Research Triangle Institute
    Inventors: C. Edgar Cook, John A. Kepler, Rupa S. Shetty, Gary S. Bartley, David Yue-wei Lee
  • 17.beta.-nitro-11.beta.-arylisteroids and their derivatives having agonist or antagonist hormonal properties
    Patent number: 6015805
    Abstract: The invention is directed to 11.beta.-arylsteroids of formula II: ##STR1## wherein R.sup.1, R.sup.6, R.sup.8, R.sup.12 and X are as defined by the specification. The compounds exhibit potent antiprogestational activity and are useful in the treatment of fibroids, endometriosis, cervical ripening prior to delivery, hormone replacement therapy and in the control of fertility.
    Type: Grant
    Filed: May 25, 1999
    Date of Patent: January 18, 2000
    Assignee: Research Triangle Research North Carolina
    Inventors: C. Edgar Cook, John A. Kepler, Rupa S. Shetty, Gary S. Bartley, David Yue-wei Lee
  • 17.beta.-nitro-11.beta.-arylsteroids and their derivatives having agonist or antagonist hormonal properties
    Patent number: 5962444
    Abstract: The invention is directed to 17.beta.-nitro-11.beta.-arylsteroids of formula I: ##STR1## wherein R.sup.1, R.sup.6, R.sup.7, R.sup.12 and X are as defined by the specification. The compounds exhibit potent antiprogestational activity and are useful in the treatment of fibroids, endometriosis, cervical ripening prior to delivery, hormone replacement therapy and in the control of fertility.
    Type: Grant
    Filed: May 29, 1998
    Date of Patent: October 5, 1999
    Assignee: Research Triangle Institute
    Inventors: C. Edgar Cook, John A. Kepler, Rupa S. Shetty, Gary S. Bartley, David Yue-wei Lee