Patents by Inventor Gayle Buller

Gayle Buller has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • 7-hydroxycoumarin-based cell-tracking reagents
    Patent number: 11175204
    Abstract: Described herein are compounds, methods, and kits for long-term tracking of cell proliferation, differentiation, and/or function. The compounds of the present invention are novel cell-tracking reagents, efficiently excitable with a 405-nm violet laser, that provide bright fluorescence intensity, uniform cell staining, and good retention within cells as well as low toxicity toward cells.
    Type: Grant
    Filed: June 24, 2016
    Date of Patent: November 16, 2021
    Assignee: Life Technologies Corporation
    Inventors: Jixiang Liu, Hee Chol Kang, Kyle Gee, Christopher Langsdorf, Jolene Bradford, Gayle Buller
  • Violet laser excitable dyes and their method of use
    Patent number: 9644099
    Abstract: The present invention provides dye compounds optimally excited at about 400 nm and have a Stokes shift of at least about 80 nm. These dyes find use in detection of analyte in a sample and the preparation of dye-conjugates.
    Type: Grant
    Filed: June 13, 2016
    Date of Patent: May 9, 2017
    Assignee: Life Technologies Corporation
    Inventors: Gayle Buller, Jixiang Liu, Stephen Yue, Jolene Ann Bradford
  • VIOLET LASER EXCITABLE DYES AND THEIR METHOD OF USE
    Publication number: 20160355682
    Abstract: The present invention provides dye compounds optimally excited at about 400 nm and have a Stokes shift of at least about 80 nm. These dyes find use in detection of analyte in a sample and the preparation of dye-conjugates.
    Type: Application
    Filed: June 13, 2016
    Publication date: December 8, 2016
    Inventors: Gayle BULLER, Jixiang Liu, Stephen Yue, Jolene Ann Bradford
  • 7-hydroxycoumarin-based cell-tracking reagents
    Patent number: 9400273
    Abstract: Described herein are compounds, methods, and kits for long-term tracking of cell proliferation, differentiation, and/or function. The compounds of the present invention are novel cell-tracking reagents, efficiently excitable with a 405-nm violet laser, that provide bright fluorescence intensity, uniform cell staining, and good retention within cells as well as low toxicity toward cells.
    Type: Grant
    Filed: July 16, 2015
    Date of Patent: July 26, 2016
    Assignee: Life Technologies Corporation
    Inventors: Jixiang Liu, Hee Chol Kang, Kyle Gee, Christopher Langsdorf, Jolene Bradford, Gayle Buller
  • VIOLET LASER EXCITABLE DYES AND THEIR METHOD OF USE
    Publication number: 20150050685
    Abstract: The present invention provides dye compounds optimally excited at about 400 nm and have a Stokes shift of at least about 80 nm. These dyes find use in detection of analyte in a sample and the preparation of dye-conjugates.
    Type: Application
    Filed: July 28, 2014
    Publication date: February 19, 2015
    Inventors: Gayle BULLER, Jixiang LIU, Stephen YUE, Jolene BRADFORD
  • Violet laser excitable dyes and their method of use
    Patent number: 8822695
    Abstract: The present invention provides dye compounds optimally excited at about 400 nm and have a Stokes shift of at least about 80 nm. These dyes find use in detection of analyte in a sample and the preparation of dye-conjugates.
    Type: Grant
    Filed: February 26, 2013
    Date of Patent: September 2, 2014
    Assignee: Life Technologies Corporation
    Inventors: Gayle Buller, Jixiang Liu, Stephen Yue, Jolene Bradford
  • Violet laser excitable dyes and their method of use
    Patent number: 8415477
    Abstract: The present invention provides dye compounds optimally excited at about 400 nm and have a Stokes shift of at least about 80 nm. These dyes find use in detection of analyte in a sample and the preparation of dye-conjugates.
    Type: Grant
    Filed: May 31, 2011
    Date of Patent: April 9, 2013
    Assignee: Life Technologies Corporation
    Inventors: Gayle Buller, Jixiang Liu, Stephen Yue, Jolene Bradford
  • Violet laser excitable dyes and their method of use
    Patent number: 8158801
    Abstract: The present invention provides dye compounds optimally excited at about 400 nm and have a Stokes shift of at least about 80 nm. These dyes find use in detection of analyte in a sample and the preparation of dye-conjugates.
    Type: Grant
    Filed: September 26, 2006
    Date of Patent: April 17, 2012
    Assignee: Life Technologies Corporation
    Inventors: Gayle Buller, Jixiang Liu, Stephen T. Yue, Jolene Bradford
  • VIOLET LASER EXCITABLE DYES AND THEIR METHOD OF USE
    Publication number: 20120004397
    Abstract: The present invention provides dye compounds optimally excited at about 400 nm and have a Stokes shift of at least about 80 nm. These dyes find use in detection of analyte in a sample and the preparation of dye-conjugates.
    Type: Application
    Filed: May 31, 2011
    Publication date: January 5, 2012
    Applicant: LIFE TECHNOLOGIES CORPORATION
    Inventors: Gayle Buller, Jixiang Liu, Stephen T. Yue, Jolene Bradford
  • VIOLET LASER EXCITABLE DYES AND THEIR METHOD OF USE
    Publication number: 20070077549
    Abstract: The present invention provides dye compounds optimally excited at about 400 nm and have a Stokes shift of at least about 80 nm. These dyes find use in detection of analyte in a sample and the preparation of dye-conjugates.
    Type: Application
    Filed: September 26, 2006
    Publication date: April 5, 2007
    Applicant: Invitrogen Corporation
    Inventors: Gayle Buller, Jixiang Liu, Stephen Yue, Jolene Bradford