Patents by Inventor Gebhard F. X. Schertler

Gebhard F. X. Schertler has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • CRYSTAL STRUCTURE
    Publication number: 20110112037
    Abstract: The invention provides a method of predicting a three dimensional structural representation of a target protein of unknown structure, or part thereof, comprising: providing the coordinates of the turkey ?1-AR structure listed in Table A, Table B, Table C or Table D, optionally varied by a root mean square deviation of residue backbone atoms of not more than 1.235 A, or selected coordinates thereof; and predicting the three-dimensional structural representation of the target protein, or part thereof, by modelling the structural representation on all or the selected coordinates of the turkey ?1-AR. The invention also provides the use of the turkey ?1-AR coordinates to select or design one or more binding partners of ?1-AR.
    Type: Application
    Filed: March 5, 2008
    Publication date: May 12, 2011
    Applicant: Heptares Therapeutics Limited BioPark
    Inventors: Antony Johannes Warne, Maria Josefa Serrano-Vega, Rouslan Moukhametzianov, Patricia C. Edwards, Richard Henderson, Andrew G.W. Leslie, Christopher Gordon Tate, Gebhard F.X. Schertler
  • Crystal structure ?adrenoreceptor
    Patent number: 7912654
    Abstract: A computer readable medium comprising atomic coordinates for the human ?2 adrenoreceptor is provided. The computer readable medium programming for displaying a molecular model of the human ?2 adrenoreceptor, programming for identifying a compound that binds to said human ?2 adrenoreceptor and/or a database of structures of known test compounds. Also provided is a method comprising computationally identifying a compound that binds to the human ?2 adrenoreceptor using the atomic coordinates.
    Type: Grant
    Filed: September 16, 2008
    Date of Patent: March 22, 2011
    Assignees: The Board of Trustees of the Leland Stanford Junior University, Heptares Therapeutics Limited
    Inventors: Brian K. Kobilka, Gebhard F. X. Schertler
  • Crystal structure beta2 adrenoreceptor
    Publication number: 20090271162
    Abstract: A computer readable medium comprising atomic coordinates for the human ?2 adrenoreceptor is provided. The computer readable medium programming for displaying a molecular model of the human ?2 adrenoreceptor, programming for identifying a compound that binds to said human ?2 adrenoreceptor and/or a database of structures of known test compounds. Also provided is a method comprising computationally identifying a compound that binds to the human ?2 adrenoreceptor using the atomic coordinates.
    Type: Application
    Filed: September 16, 2008
    Publication date: October 29, 2009
    Inventors: Brian K. Kobilka, Gebhard F. X. Schertler