Patents by Inventor Gene Tan

Gene Tan has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20240146403
    Abstract: Various aspects of the present disclosure generally relate to wireless communication. In some aspects, a user equipment (UE) may detect a trigger event associated with a satellite communication link, the trigger event being based at least in part on at least one of: a status of an access link associated with the UE, or information associated with another device or a component of the UE. The UE may transmit a communication via the satellite communication link based at least in part on detecting the trigger event. Numerous other aspects are described.
    Type: Application
    Filed: July 27, 2023
    Publication date: May 2, 2024
    Inventors: Francesco GRILLI, Vivek KHANNA, Sivaramakrishna VEEREPALLI, Shailesh PATIL, Gene Wesley MARSH, Cheng TAN, Jungsik PARK, Carl HARDIN, Rashmin ANJARIA, Shuanshuan WU
  • Publication number: 20230126396
    Abstract: The present disclosure is directed towards chimeric glycoproteins wherein the clip region, a core region, a flap region, and a transmembrane and cytoplasmic domain are defined by starting from the amino terminus of the protein, these domains are comprised of the following amino acid residue ranges: clip, 1 through 40 to 60; core, 40 to 60 through 249 to 281; flap, 249 to 281 through 419 to 459; the transmembrane domain is comprised of amino acids 460 through 480, and the remaining amino acids 481 through 525 comprise the cytoplasmic domain; and wherein the clip, core, flap, transmembrane, and cytoplasmic domain comprise a chimeric combination of at least two lyssavirus, wherein the chimeric glycoprotein is advantageously inserted into a rabies-based vaccine vector.
    Type: Application
    Filed: October 13, 2022
    Publication date: April 27, 2023
    Inventors: Matthias Schnell, Christine Rettew Fisher, Christoph Wirblich, Gene Tan
  • Patent number: 11484586
    Abstract: The present disclosure is directed towards chimeric glycoproteins wherein the clip region, a core region, a flap region, and a transmembrane and cytoplasmic domain are defined by starting from the amino terminus of the protein, these domains are comprised of the following amino acid residue ranges: clip, 1 through 40 to 60; core, 40 to 60 through 249 to 281; flap, 249 to 281 through 419 to 459; the transmembrane domain is comprised of amino acids 460 through 480, and the remaining amino acids 481 through 525 comprise the cytoplasmic domain; and wherein the clip, core, flap, transmembrane, and cytoplasmic domain comprise a chimeric combination of at least two lyssavirus, wherein the chimeric glycoprotein is advantageously inserted into a rabies-based vaccine vector.
    Type: Grant
    Filed: June 13, 2018
    Date of Patent: November 1, 2022
    Assignees: Thomas Jefferson University, ICAHN School of Medicine at Mount Sinai
    Inventors: Matthias Schnell, Christine Rettew Fisher, Christoph Wirblich, Gene Tan
  • Publication number: 20220017605
    Abstract: In one aspect, provided herein are antibodies that bind to Zika virus non-structural protein 1 (NS1) and compositions comprising the same. In a specific embodiment, such antibodies or compositions thereof may be used to passively immunize a subject against Zika virus. In another embodiment, such antibodies or compositions thereof may be used to diagnose a Zika virus infection. In another aspect, provided herein are recombinant NS 1 polypeptides and compositions comprising the same that may be used to immunize a subject against Zika virus disease.
    Type: Application
    Filed: October 30, 2019
    Publication date: January 20, 2022
    Applicant: ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI
    Inventors: Mark BAILEY, Peter PALESE, Gene TAN
  • Publication number: 20210145959
    Abstract: The present disclosure is directed towards chimeric glycoproteins wherein the clip region, a core region, a flap region, and a transmembrane and cytoplasmic domain are defined by starting from the amino terminus of the protein, these domains are comprised of the following amino acid residue ranges: clip, 1 through 40 to 60; core, 40 to 60 through 249 to 281; flap, 249 to 281 through 419 to 459; the transmembrane domain is comprised of amino acids 460 through 480, and the remaining amino acids 481 through 525 comprise the cytoplasmic domain; and wherein the clip, core, flap, transmembrane, and cytoplasmic domain comprise a chimeric combination of at least two lyssavirus, wherein the chimeric glycoprotein is advantageously inserted into a rabies-based vaccine vector.
    Type: Application
    Filed: June 13, 2018
    Publication date: May 20, 2021
    Applicants: Thomas Jefferson University, ICAHN School of Medicine at Mount Sinai
    Inventors: Schnell Matthias, Christine Rettew Fisher, Christoph Wirblich, Gene Tan
  • Patent number: 10544207
    Abstract: Provided herein are antibodies that cross-react with hemagglutinin from strains of influenza virus of the same subtype or different subtypes, host cells for producing such antibodies, and kits comprising such antibodies. Also provided herein are compositions comprising antibodies that cross-react with hemagglutinin from strains of influenza virus of the same subtype or different subtypes and methods of using such antibodies to diagnose, prevent or treat influenza virus disease.
    Type: Grant
    Filed: January 22, 2018
    Date of Patent: January 28, 2020
    Assignee: Icahn School of Medicine at Mount Sinai
    Inventors: Peter Palese, Adolfo Garcia-Sastre, Gene Tan
  • Publication number: 20180265573
    Abstract: Provided herein are antibodies that cross-react with hemagglutinin from strains of influenza virus of the same subtype or different subtypes, host cells for producing such antibodies, and kits comprising such antibodies. Also provided herein are compositions comprising antibodies that cross-react with hemagglutinin from strains of influenza virus of the same subtype or different subtypes and methods of using such antibodies to diagnose, prevent or treat influenza virus disease.
    Type: Application
    Filed: January 22, 2018
    Publication date: September 20, 2018
    Applicant: ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI
    Inventors: Peter Palese, Adolfo Garcia-Sastre, Gene Tan
  • Patent number: 9908930
    Abstract: Provided herein are antibodies that cross-react with hemagglutinin from strains of influenza virus of the same subtype or different subtypes, host cells for producing such antibodies, and kits comprising such antibodies. Also provided herein are compositions comprising antibodies that cross-react with hemagglutinin from strains of influenza virus of the same subtype or different subtypes and methods of using such antibodies to diagnose, prevent or treat influenza virus disease.
    Type: Grant
    Filed: March 13, 2014
    Date of Patent: March 6, 2018
    Assignee: ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI
    Inventors: Peter Palese, Adolfo Garcia-Sastre, Gene Tan
  • Publication number: 20160137721
    Abstract: Provided herein are antibodies that cross-react with hemagglutinin from strains of influenza virus of the same subtype or different subtypes, host cells for producing such antibodies, and kits comprising such antibodies. Also provided herein are compositions comprising antibodies that cross-react with hemagglutinin from strains of influenza virus of the same subtype or different subtypes and methods of using such antibodies to diagnose, prevent or treat influenza virus disease.
    Type: Application
    Filed: March 13, 2014
    Publication date: May 19, 2016
    Applicant: ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI
    Inventors: Peter Palese, Adolfo Garcia-Sastre, Gene Tan