Patents by Inventor Geoffrey W. Henson

Geoffrey W. Henson has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • METHODS TO MOBILIZE PROGENITOR/STEM CELLS
    Publication number: 20190216773
    Abstract: Methods to elevate progenitor and stem cell counts in animal subjects using compounds which bind to the chemokine receptor CXCR4 are disclosed.
    Type: Application
    Filed: August 21, 2018
    Publication date: July 18, 2019
    Inventors: Gary J. BRIDGER, Michael J. ABRAMS, Geoffrey W. HENSON, Ronald Trevor MACFARLAND, Gary B. CALANDRA, Hal E. BROXMEYER, David C. DALE
  • METHODS TO MOBILIZE PROGENITOR/STEM CELLS
    Publication number: 20170049747
    Abstract: Methods to elevate progenitor and stem cell counts in animal subjects using compounds which bind to the chemokine receptor CXCR4 are disclosed.
    Type: Application
    Filed: March 18, 2016
    Publication date: February 23, 2017
    Inventors: Gary J. BRIDGER, Michael J. ABRAMS, Geoffrey W. HENSON, Ronald Trevor MACFARLAND, Gary B. CALANDRA, Hal E. BROXMEYER, David C. DALE
  • METHODS TO MOBILIZE PROGENITOR/STEM CELLS
    Publication number: 20150246019
    Abstract: Methods to elevate progenitor and stem cell counts in animal subjects using compounds which bind to the chemokine receptor CXCR4 are disclosed.
    Type: Application
    Filed: October 3, 2014
    Publication date: September 3, 2015
    Inventors: Gary J. BRIDGER, Michael J. Abrams, Geoffrey W. Henson, Ronald Trevor Macfarland, Gary B. Calandra, Hal E. Broxmeyer, David C. Dale
  • METHODS TO MOBILIZE PROGENITOR/STEM CELLS
    Publication number: 20110129448
    Abstract: Methods to elevate progenitor and stem cell counts in animal subjects using compounds which bind to the chemokine receptor CXCR4 are disclosed.
    Type: Application
    Filed: February 8, 2011
    Publication date: June 2, 2011
    Applicant: Genzyme Corporation
    Inventors: Gary J. BRIDGER, Michael J. Abrams, Geoffrey W. Henson, Ronald Trevor MacFarland, Gary B. Calandra, Hal E. Broxmeyer, David C. Dale
  • Methods to mobilize progenitor/stem cells
    Patent number: 7935692
    Abstract: Methods to elevate progenitor and stem cell counts in animal subjects using compounds which bind to the chemokine receptor CXCR4 are disclosed.
    Type: Grant
    Filed: November 8, 2005
    Date of Patent: May 3, 2011
    Assignee: Genzyme Corporation
    Inventors: Gary J. Bridger, Michael J. Abrams, Geoffrey W. Henson, Ronald Trevor MacFarland, Gary B. Calandra, Hal E. Broxmeyer, David C. Dale
  • Methods to mobilize progenitor/stem cells
    Patent number: 7897590
    Abstract: Methods to elevate progenitor and stem cell counts in animal subjects using compounds which bind to the chemokine receptor CXCR4 are disclosed.
    Type: Grant
    Filed: August 20, 2007
    Date of Patent: March 1, 2011
    Assignee: Genzyme Corporation
    Inventors: Gary J. Bridger, Michael J. Abrams, Geoffrey W. Henson, Ronald Trevor MacFarland, Gary B. Calandra, Hal E. Broxmeyer, David C. Dale
  • Methods to mobilize progenitor/stem cells
    Patent number: 7169750
    Abstract: Methods to elevate progenitor and stem cell counts in animal subjects using compounds which bind to the chemokine receptor CXCR4 are disclosed. Preferred embodiments of such compounds are of the formula Z-linker-Z? ??(1) or pharmaceutically acceptable salt thereof wherein Z is of the formula wherein A comprises a monocyclic or bicyclic fused ring system containing at least one N and B is H or an organic moiety of 1–20 atoms, Z? is of the formula —Ar(Y)j; wherein Ar is an aromatic or heteroaromatic moiety, and each Y is independently a non-interfering substituent and j is 0–3; and “linker” represents a bond, alkylene (1–6C) or may comprise aryl, fused aryl, oxygen atoms contained in an alkylene chain, or may contain keto groups or nitrogen or sulfur atoms.
    Type: Grant
    Filed: June 5, 2003
    Date of Patent: January 30, 2007
    Assignee: Anormed, Inc.
    Inventors: Gary Bridger, Michael J. Abrams, Geoffrey W. Henson, Ronald T. MacFarland, Gary B. Calandra
  • Methods to mobilize progenitor/stem cells
    Patent number: 6987102
    Abstract: Certain nitrogen-containing compounds that bind the chemokine receptor CXCR4 are able to mobilize progenitor and/or stem cells into the peripheral blood to permit harvesting them for stem cell transplantation.
    Type: Grant
    Filed: July 30, 2002
    Date of Patent: January 17, 2006
    Assignee: Anormed, Inc.
    Inventors: Gary J. Bridger, Michael J. Abrams, Geoffrey W. Henson, Ronald Trevor MacFarland, Gary B. Calandra, Hal E. Broxmeyer, David C. Dale
  • Methods to enhance white blood cell count
    Patent number: 6670354
    Abstract: Methods to elevate white blood cell counts in animal subjects using compounds of formula (1) are disclosed.
    Type: Grant
    Filed: January 4, 2002
    Date of Patent: December 30, 2003
    Assignee: AnorMed, Inc.
    Inventors: Ronald Trevor MacFarland, Andrew W. Millar, Gary Bridger, Michael J. Abrams, Geoffrey W. Henson
  • Methods to mobilize progenitor/stem cells
    Publication number: 20030130250
    Abstract: Methods to elevate progenitor and stem cell counts in animal subjects using compounds which bind to the chemokine receptor CXCR4 are disclosed.
    Type: Application
    Filed: July 30, 2002
    Publication date: July 10, 2003
    Inventors: Gary J. Bridger, Michael J. Abrams, Geoffrey W. Henson, Ronald Trevor MacFarland, Gary B. Calandra
  • Methods to enhance white blood cell count
    Publication number: 20020058653
    Abstract: Methods to elevate white blood cell counts in animal subjects using compounds of formula (1) are disclosed.
    Type: Application
    Filed: January 4, 2002
    Publication date: May 16, 2002
    Inventors: Ronald Trevor MacFarland, Andrew W. Millar, Gary Bridger, Michael J. Abrams, Geoffrey W. Henson
  • Methods to enhance white blood cell count
    Patent number: 6365583
    Abstract: Methods to elevate white blood cell counts in animal subjects using compounds of formula (1) are disclosed.
    Type: Grant
    Filed: February 1, 2000
    Date of Patent: April 2, 2002
    Assignee: AnorMED, Inc.
    Inventors: Ronald Trevor MacFarland, Andrew W. Millar, Gary Bridger, Michael J. Abrams, Geoffrey W. Henson
  • Anti-tumor platinum complexes
    Patent number: 5547982
    Abstract: Platinum complexes, having anti-tumor activity, which include at least one functional ketone group or aldehyde, optionally conjugated as a linkable hydrazone complex. The functional ketone and aldehyde groups and the functionalized hydrazone complexes are linkable to antibodies, proteins, peptides and compounds having free amine, hydrazine or hydrazide functionality. Such agents are useful as targeted site-specific or disease specific chemotherapeutic agents.
    Type: Grant
    Filed: February 27, 1995
    Date of Patent: August 20, 1996
    Assignee: Johnson Matthey, Inc.
    Inventors: Michael J. Abrams, Gerald E. Bossard, Robert C. Brooks, Geoffrey W. Henson, Jean F. Vollano
  • Macromolecular platinum antitumor compounds
    Patent number: 4793986
    Abstract: A composition comprising a pharmaceutically acceptable polysaccharide carrier which has been chemically activated and then linked to platinum in either a +2 or +4 oxidation state through a bidentate oxygen-containing ligand including an amine group coupled to the activated polysaccharide. The composition may be used to link platinum metal remotely to a monoclonal antibody via the oxygen-containing ligand and the polysaccharide carrier such as dextran. The composition is optionally radiolabeled.
    Type: Grant
    Filed: February 25, 1987
    Date of Patent: December 27, 1988
    Assignee: Johnson Matthey, Inc.
    Inventors: Anthony J. Serino, Geoffrey W. Henson, David A. Schwartz, Donald H. Picker