Patents by Inventor Georg Börtlein
Georg Börtlein has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 11938022Abstract: A transcatheter valve prosthesis and a method for implanting the prosthesis in a heart are disclosed. The prosthesis includes a tubular body a coupled to a prosthetic valve. A fabric may be disposed on an outer surface of the tubular body. The method includes partially deploying the tubular body from a catheter to at position distal of a distal edge of a native valve leaflet, and moving the catheter such that the deployed outflow end portion of the tubular body engages the distal edge of the native valve leaflet and lifts the native valve leaflet in the proximal direction towards an atrial chamber of the heart. Then, the tubular body can be fully deployed such that the native valve leaflet is captured between the outflow end portion and the inflow end portion.Type: GrantFiled: May 25, 2021Date of Patent: March 26, 2024Assignee: HIGHLIFE SASInventors: Malek Nasr, Georg Börtlein
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Patent number: 11642220Abstract: A transcatheter atrio-ventricular valve prosthesis for functional replacement of an atrio-ventricular heart valve in a connection channel, the prosthesis comprising a radially expandable tubular body extending along an axis, and a valve arranged within and attached to the tubular body. The tubular body is provided with an outer circumferential groove which is open to the radial outside of the tubular body, whereby the tubular body is separated by the outer circumferential groove into first and second body sections. The tubular body is provided with a first plurality of projections which extend from the first or second body section in an axial direction of the tubular body and each of which has a free end arranged to overlap the outer circumferential groove. An elongate outer member may be disposed at the exterior of the connection channel wall structure at a level of the circumferential groove.Type: GrantFiled: October 1, 2020Date of Patent: May 9, 2023Assignee: HIGHLIFE SASInventors: Georg Börtlein, Malek Nasr
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Patent number: 11484407Abstract: A replacement heart valve system and a method of implanting a replacement heart valve in a patient. The replacement heart valve system includes a radially self-expandable tubular body and a valve including a plurality of leaflets coupled to the tubular body. The tubular body includes interconnected struts defining circumferential rows of cells, and has an outflow end and an inflow end that flares radially outward so as to have a larger outer diameter than that of the outflow end. A first row of proximal-most cells formed at the inflow end includes circumferentially adjacent cells that are disconnected from each other so as to be spaced from each other in the circumferential direction. A method of implanting the replacement heart valve includes delivering from a delivery catheter the tubular body, and expanding the tubular body such that the proximal-most cells are disposed against the native heart valve annulus.Type: GrantFiled: January 7, 2020Date of Patent: November 1, 2022Assignee: HIGHLIFE SASInventors: Will Wang, Malek Nasr, Georg Börtlein, Garrett Offerman, Gilbert Madrid, Martin Rothman, Glenn Balke, Eric Diep
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Publication number: 20210401572Abstract: A transcatheter valve prosthesis and a method for implanting the prosthesis in a heart are disclosed. The prosthesis includes a tubular body a coupled to a prosthetic valve. A fabric may be disposed on an outer surface of the tubular body. The method includes partially deploying the tubular body from a catheter to at position distal of a distal edge of a native valve leaflet, and moving the catheter such that the deployed outflow end portion of the tubular body engages the distal edge of the native valve leaflet and lifts the native valve leaflet in the proximal direction towards an atrial chamber of the heart. Then, the tubular body can be fully deployed such that the native valve leaflet is captured between the outflow end portion and the inflow end portion.Type: ApplicationFiled: May 25, 2021Publication date: December 30, 2021Applicant: HIGHLIFE SASInventors: Malek NASR, Georg BÖRTLEIN
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Publication number: 20210205077Abstract: A replacement heart valve system and a method of implanting a replacement heart valve in a patient. The replacement heart valve system includes a radially self-expandable tubular body and a valve including a plurality of leaflets coupled to the tubular body. The tubular body includes interconnected struts defining circumferential rows of cells, and has an outflow end and an inflow end that flares radially outward so as to have a larger outer diameter than that of the outflow end. A first row of proximal-most cells formed at the inflow end includes circumferentially adjacent cells that are disconnected from each other so as to be spaced from each other in the circumferential direction. A method of implanting the replacement heart valve includes delivering from a delivery catheter the tubular body, and expanding the tubular body such that the proximal-most cells are disposed against the native heart valve annulus.Type: ApplicationFiled: January 7, 2020Publication date: July 8, 2021Applicant: HIGHLIFE SASInventors: Will WANG, Malek NASR, Georg BÖRTLEIN, Garrett OFFERMAN, Gilbert MADRID, Martin ROTHMAN, Glenn BALKE, Eric DIEP
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Publication number: 20210015605Abstract: A transcatheter atrio-ventricular valve prosthesis for functional replacement of an atrio-ventricular heart valve in a connection channel, the prosthesis comprising a radially expandable tubular body extending along an axis, and a valve arranged within and attached to the tubular body. The tubular body is provided with an outer circumferential groove which is open to the radial outside of the tubular body, whereby the tubular body is separated by the outer circumferential groove into first and second body sections. The tubular body is provided with a first plurality of projections which extend from the first or second body section in an axial direction of the tubular body and each of which has a free end arranged to overlap the outer circumferential groove. An elongate outer member may be disposed at the exterior of the connection channel wall structure at a level of the circumferential groove.Type: ApplicationFiled: October 1, 2020Publication date: January 21, 2021Applicant: HIGHLIFE SASInventors: Georg BÖRTLEIN, Malek NASR
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Patent number: 10828157Abstract: A transcatheter atrio-ventricular valve prosthesis for functional replacement of an atrio-ventricular heart valve in a connection channel, the prosthesis comprising a radially expandable tubular body extending along an axis, and a valve arranged within and attached to the tubular body. The tubular body is provided with an outer circumferential groove which is open to the radial outside of the tubular body, whereby the tubular body is separated by the outer circumferential groove into first and second body sections. The tubular body is provided with a first plurality of projections which extend from the first or second body section in an axial direction of the tubular body and each of which has a free end arranged to overlap the outer circumferential groove. An elongate outer member may be disposed at the exterior of the connection channel wall structure at a level of the circumferential groove.Type: GrantFiled: March 2, 2017Date of Patent: November 10, 2020Assignee: HIGHLIFE SASInventors: Georg Börtlein, Malek Nasr
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Patent number: 10195031Abstract: An implant for implantation around a circumferential tissue structure in a heart, includes a flexible elongated component having a longitudinal axis and a first distal end portion, a second distal end portion and an intermediate portion extending between the first and second distal end portions, and an inner lumen extending longitudinally between the first and second distal end portions and through the intermediate portion; and a locking member for allowing the first distal end portion to be fixedly connected to the second distal end portion so as to provide the elongated component as a closed loop. The first distal end portion is provided with a first distal opening which connects the inner lumen with an outside of the component. The second distal end portion is provided with a second distal opening which connects the inner lumen with the outside of the component.Type: GrantFiled: May 3, 2016Date of Patent: February 5, 2019Assignee: HIGHLIFE SASInventors: Malek Nasr, Georg Börtlein, Jean-Francois Ollivier, Philippe D'Hiver
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Patent number: 10080651Abstract: A system for implanting a heart valve includes a radially self-expandable tubular body having an inflow end and an outflow end and a preformed groove disposed at an outer surface of the tubular body between the inflow end and the outflow end. The preformed groove extends at least partially around the tubular body and has a circumferential opening facing radially outward of the tubular body. A valve is disposed within and is attached to the tubular body, and an elongate outer member is configured to form a loop encircling the preformed groove so as to guide portions of native valve leaflets and/or chords into the preformed groove. The outflow end of the tubular body includes a frustoconical shape that slopes radially outward from the preformed groove toward the outflow end when the outflow end but not the inflow end has been released from a delivery catheter.Type: GrantFiled: March 11, 2014Date of Patent: September 25, 2018Assignee: HIGHLIFE SASInventors: Georg Börtlein, Malek Nasr
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Patent number: 10064719Abstract: A system for implanting a heart valve includes a radially self-expandable tubular body having an inflow end and an outflow end and a projection extending from a side surface of the tubular body toward the inflow end. The system further includes a valve disposed within and attached to the tubular body, and may include fabric that forms a pouch between the tubular body and the projection.Type: GrantFiled: March 11, 2014Date of Patent: September 4, 2018Assignee: HIGHLIFE SASInventors: Georg Börtlein, Malek Nasr
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Publication number: 20180116799Abstract: An implant for implantation around a circumferential tissue structure in a heart, includes a flexible elongated component having a longitudinal axis and a first distal end portion, a second distal end portion and an intermediate portion extending between the first and second distal end portions, and an inner lumen extending longitudinally between the first and second distal end portions and through the intermediate portion; and a locking member for allowing the first distal end portion to be fixedly connected to the second distal end portion so as to provide the elongated component as a closed loop. The first distal end portion is provided with a first distal opening which connects the inner lumen with an outside of the component. The second distal end portion is provided with a second distal opening which connects the inner lumen with the outside of the component.Type: ApplicationFiled: May 3, 2016Publication date: May 3, 2018Applicant: HIGHLIFE SASInventors: Malek NASR, Georg BÖRTLEIN, Jean-Francois OLLIVIER, Philippe D'HIVER
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Patent number: 9895224Abstract: A treatment catheter system for treatment of a heart valve includes a circumferential valve tissue structure and an elongate catheter member, and has an inner lumen, proximal and distal end portions. The system includes a catching component which can be positioned at the distal end portion of the catheter member to be non-separable from the catheter member. An outer member extends circumferentially around the catheter member. The circumferential valve tissue structure is correspondingly arranged between the catheter member and the outer member. A catching mechanism reduces a radial distance between the catheter member and the outer member to catch the valve tissue between the outer member and the catheter member via a catching opening to immobilize and treat the caught valve tissue on the distal end portion of the catheter member.Type: GrantFiled: September 12, 2012Date of Patent: February 20, 2018Assignee: HIGHLIFE SASInventors: Georg Börtlein, Malek Nasr
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Patent number: 9889003Abstract: A system for implanting a heart valve that includes a radially self-expandable tubular body having an inflow end and a preformed groove disposed at an outer surface of the tubular body between the inflow end and the outflow end, wherein the preformed groove extends at least partially around the tubular body and having a circumferential opening facing radially outward of the tubular body. A valve may be disposed within and attached to the tubular body. Additionally, a trapping member may be configured to form at least a partial loop encircling the preformed groove so as to trap portions of native valve leaflets and/or chords in the preformed groove, the trapping member including one or more barbs.Type: GrantFiled: March 11, 2014Date of Patent: February 13, 2018Assignee: HIGHLIFE SASInventors: Georg Börtlein, Malek Nasr
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Patent number: 9848982Abstract: A system for implanting a heart valve that includes a radially self-expandable tubular body having an inflow end and a preformed groove disposed at an outer surface of the tubular body between the inflow end and the outflow end, wherein the preformed groove extends at least partially around the tubular body and having a circumferential opening facing radially outward of the tubular body. A valve may be disposed within and attached to the tubular body. Additionally, a trapping member may be configured to form at least a partial loop encircling the preformed groove so as to trap portions of native valve leaflets and/or chords in the preformed groove, the trapping member including one or more barbs.Type: GrantFiled: March 11, 2014Date of Patent: December 26, 2017Assignee: HIGHLIFE SASInventors: Georg Börtlein, Malek Nasr
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Patent number: 9763779Abstract: A system for implanting a heart valve includes a radially self-expandable tubular body having an inflow end and an outflow end, a decorrelation portion, and a preformed groove disposed at an outer surface of the tubular body between the decorrelation portion and the outflow end. The preformed groove extends at least partially around the tubular body, and has a circumferential opening facing radially outward of the tubular body. A valve is disposed within and attached to the tubular body. The decorrelation portion is configured to dissociate axial and radial movements between the inflow end of the tubular body and the outflow end of the tubular body.Type: GrantFiled: March 11, 2014Date of Patent: September 19, 2017Assignee: HIGHLIFE SASInventors: Georg Börtlein, Malek Nasr
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Publication number: 20170209261Abstract: A transcatheter atrio-ventricular valve prosthesis for functional replacement of an atrio-ventricular heart valve in a connection channel, the prosthesis comprising a radially expandable tubular body extending along an axis, and a valve arranged within and attached to the tubular body. The tubular body is provided with an outer circumferential groove which is open to the radial outside of the tubular body, whereby the tubular body is separated by the outer circumferential groove into first and second body sections. The tubular body is provided with a first plurality of projections which extend from the first or second body section in an axial direction of the tubular body and each of which has a free end arranged to overlap the outer circumferential groove. An elongate outer member may be disposed at the exterior of the connection channel wall structure at a level of the circumferential groove.Type: ApplicationFiled: March 2, 2017Publication date: July 27, 2017Applicant: HIGHLIFE SASInventors: Georg BÖRTLEIN, Malek NASR
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Patent number: 9687343Abstract: A system for implanting a heart valve includes a radially self-expandable tubular body having an inflow end and an outflow end and a preformed groove disposed at an outer surface of the tubular body between the inflow end and the outflow end. The preformed groove extends at least partially around the tubular body, and has a circumferential opening facing radially outward of the tubular body. A valve is disposed within and attached to the tubular body, and a trapping member is configured to be moved into the preformed groove and form at least a partial loop around the preformed groove. An insertion member is configured to push the trapping member into the preformed groove. Additionally, a coupling member can provide a releasable attachment between the trapping member and the insertion member.Type: GrantFiled: March 11, 2014Date of Patent: June 27, 2017Assignee: HIGHLIFE SASInventors: Georg Börtlein, Malek Nasr
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Patent number: 9662206Abstract: A transcatheter atrio-ventricular valve prosthesis for functional replacement of an atrio-ventricular heart valve in a connection channel, the prosthesis comprising a radially expandable tubular body extending along an axis, and a valve arranged within and attached to the tubular body. The tubular body is provided with an outer circumferential groove which is open to the radial outside of the tubular body, whereby the tubular body is separated by the outer circumferential groove into first and second body sections. The tubular body is provided with a first plurality of projections which extend from the first or second body section in an axial direction of the tubular body and each of which has a free end arranged to overlap the outer circumferential groove. An elongate outer member may be disposed at the exterior of the connection channel wall structure at a level of the circumferential groove.Type: GrantFiled: June 13, 2012Date of Patent: May 30, 2017Assignee: HIGHLIFE SASInventors: Georg Börtlein, Malek Nasr
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Patent number: 9387075Abstract: A method for implanting a heart valve includes advancing an elongate outer member from a first delivery catheter to form a loop around native valve leaflets and/or chords of a native valve without substantially occluding the native valve. The method further includes partially deploying from a second delivery catheter a radially self-expandable tubular body having a valve disposed within a lumen of the tubular body, and a preformed groove disposed at an outer surface of the tubular body. The preformed groove extends at least partially around the tubular body, and has a circumferential opening facing radially outward of the tubular body. When the tubular body is partially deployed, the native valve is substantially occluded. Additionally, the method includes moving the loop into the preformed groove after partially deploying the tubular body. The native valve is no longer substantially occluded after fully deploying the tubular body from the second delivery catheter.Type: GrantFiled: March 11, 2014Date of Patent: July 12, 2016Assignee: HIGHLIFE SASInventors: Georg Börtlein, Malek Nasr
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Patent number: 9358108Abstract: A system for implanting a heart valve includes a radially self-expandable tubular body having a preformed groove disposed at an outer surface of the tubular body, and a valve disposed within the tubular body. The preformed groove extends at least partially around the tubular body, and has a circumferential opening facing radially outward. A trapping member is configured to be disposed within the preformed groove on the outer surface of the tubular body and form at least a partial loop around the tubular body. The circumferential opening of the preformed groove is relatively larger when an outflow end of the tubular body has been deployed from a catheter and an inflow end of the tubular body is disposed within the catheter, and the circumferential opening of the preformed groove is relatively smaller when both the outflow end and the inflow end are fully deployed from the catheter.Type: GrantFiled: March 11, 2014Date of Patent: June 7, 2016Assignee: HIGHLIFE SASInventors: Georg Börtlein, Malek Nasr