Patents by Inventor Georg Bortlein
Georg Bortlein has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20180116799Abstract: An implant for implantation around a circumferential tissue structure in a heart, includes a flexible elongated component having a longitudinal axis and a first distal end portion, a second distal end portion and an intermediate portion extending between the first and second distal end portions, and an inner lumen extending longitudinally between the first and second distal end portions and through the intermediate portion; and a locking member for allowing the first distal end portion to be fixedly connected to the second distal end portion so as to provide the elongated component as a closed loop. The first distal end portion is provided with a first distal opening which connects the inner lumen with an outside of the component. The second distal end portion is provided with a second distal opening which connects the inner lumen with the outside of the component.Type: ApplicationFiled: May 3, 2016Publication date: May 3, 2018Applicant: HIGHLIFE SASInventors: Malek NASR, Georg BÖRTLEIN, Jean-Francois OLLIVIER, Philippe D'HIVER
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Patent number: 9895224Abstract: A treatment catheter system for treatment of a heart valve includes a circumferential valve tissue structure and an elongate catheter member, and has an inner lumen, proximal and distal end portions. The system includes a catching component which can be positioned at the distal end portion of the catheter member to be non-separable from the catheter member. An outer member extends circumferentially around the catheter member. The circumferential valve tissue structure is correspondingly arranged between the catheter member and the outer member. A catching mechanism reduces a radial distance between the catheter member and the outer member to catch the valve tissue between the outer member and the catheter member via a catching opening to immobilize and treat the caught valve tissue on the distal end portion of the catheter member.Type: GrantFiled: September 12, 2012Date of Patent: February 20, 2018Assignee: HIGHLIFE SASInventors: Georg Börtlein, Malek Nasr
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Patent number: 9889003Abstract: A system for implanting a heart valve that includes a radially self-expandable tubular body having an inflow end and a preformed groove disposed at an outer surface of the tubular body between the inflow end and the outflow end, wherein the preformed groove extends at least partially around the tubular body and having a circumferential opening facing radially outward of the tubular body. A valve may be disposed within and attached to the tubular body. Additionally, a trapping member may be configured to form at least a partial loop encircling the preformed groove so as to trap portions of native valve leaflets and/or chords in the preformed groove, the trapping member including one or more barbs.Type: GrantFiled: March 11, 2014Date of Patent: February 13, 2018Assignee: HIGHLIFE SASInventors: Georg Börtlein, Malek Nasr
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Patent number: 9848982Abstract: A system for implanting a heart valve that includes a radially self-expandable tubular body having an inflow end and a preformed groove disposed at an outer surface of the tubular body between the inflow end and the outflow end, wherein the preformed groove extends at least partially around the tubular body and having a circumferential opening facing radially outward of the tubular body. A valve may be disposed within and attached to the tubular body. Additionally, a trapping member may be configured to form at least a partial loop encircling the preformed groove so as to trap portions of native valve leaflets and/or chords in the preformed groove, the trapping member including one or more barbs.Type: GrantFiled: March 11, 2014Date of Patent: December 26, 2017Assignee: HIGHLIFE SASInventors: Georg Börtlein, Malek Nasr
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Publication number: 20170273785Abstract: A prosthetic valve assembly for use in replacing a deficient native valve comprises a replacement valve supported on an expandable prosthesis frame. If desired, one or more expandable anchors may be used. The prosthesis frame, which entirely supports the valve annulus, valve leaflets, and valve commissure points, is configured to be collapsible for transluminal delivery and expandable to contact the anatomical annulus of the native valve when the assembly is properly positioned. Portions of the prosthesis frame may expand to a preset diameter to maintain coaptivity of the replacement valve and to prevent occlusion of the coronary ostia. The prosthesis frame is compressible about a catheter, and restrained from expanding by an outer sheath. The catheter may be inserted inside a lumen within the body, such as the femoral artery, and delivered to a desired location, such as the heart.Type: ApplicationFiled: April 6, 2017Publication date: September 28, 2017Inventors: Jacques Seguin, Georg Bortlein, Than Nguyen, Edward Pannek
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Patent number: 9770332Abstract: A catheter member (1) for interacting with a circumferential tissue structure (10) includes an elongate primary catheter (70) which has an inner lumen (80) and which extends along a longitudinal axis (90) and has a distal end portion (100), first (120) and second (130) elongate secondary catheters each comprising a distal end portion (140, 150) and an inner lumen (160, 170), and each to be disposed in the inner lumen (80) of the primary catheter (70) to be moveable relatively thereto and exposable from the distal end portion thereof, and a first flexing mechanism (191) to provide the distal end portion (140, 150) of the first (120) and/or second (130) secondary catheter with a tendency to assume a first secondary bent shape, wherein the distal end portion of one or both of the first and second secondary catheters is provided so as to be able to be flexed by the first flexing mechanism to form an arm portion (126, 136) substantially transverse to the direction of the longitudinal axis (90) of the primary catheType: GrantFiled: March 5, 2013Date of Patent: September 26, 2017Assignee: HIGHLIFE SASInventors: Georg Bortlein, Malek Nasr
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Patent number: 9763779Abstract: A system for implanting a heart valve includes a radially self-expandable tubular body having an inflow end and an outflow end, a decorrelation portion, and a preformed groove disposed at an outer surface of the tubular body between the decorrelation portion and the outflow end. The preformed groove extends at least partially around the tubular body, and has a circumferential opening facing radially outward of the tubular body. A valve is disposed within and attached to the tubular body. The decorrelation portion is configured to dissociate axial and radial movements between the inflow end of the tubular body and the outflow end of the tubular body.Type: GrantFiled: March 11, 2014Date of Patent: September 19, 2017Assignee: HIGHLIFE SASInventors: Georg Börtlein, Malek Nasr
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Publication number: 20170209261Abstract: A transcatheter atrio-ventricular valve prosthesis for functional replacement of an atrio-ventricular heart valve in a connection channel, the prosthesis comprising a radially expandable tubular body extending along an axis, and a valve arranged within and attached to the tubular body. The tubular body is provided with an outer circumferential groove which is open to the radial outside of the tubular body, whereby the tubular body is separated by the outer circumferential groove into first and second body sections. The tubular body is provided with a first plurality of projections which extend from the first or second body section in an axial direction of the tubular body and each of which has a free end arranged to overlap the outer circumferential groove. An elongate outer member may be disposed at the exterior of the connection channel wall structure at a level of the circumferential groove.Type: ApplicationFiled: March 2, 2017Publication date: July 27, 2017Applicant: HIGHLIFE SASInventors: Georg BÖRTLEIN, Malek NASR
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Patent number: 9687343Abstract: A system for implanting a heart valve includes a radially self-expandable tubular body having an inflow end and an outflow end and a preformed groove disposed at an outer surface of the tubular body between the inflow end and the outflow end. The preformed groove extends at least partially around the tubular body, and has a circumferential opening facing radially outward of the tubular body. A valve is disposed within and attached to the tubular body, and a trapping member is configured to be moved into the preformed groove and form at least a partial loop around the preformed groove. An insertion member is configured to push the trapping member into the preformed groove. Additionally, a coupling member can provide a releasable attachment between the trapping member and the insertion member.Type: GrantFiled: March 11, 2014Date of Patent: June 27, 2017Assignee: HIGHLIFE SASInventors: Georg Börtlein, Malek Nasr
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Publication number: 20170172554Abstract: A catheter member for interacting with a circumferential tissue structure includes: an elongate primary catheter having at least one inner lumen and extending along a longitudinal axis; first and second elongate secondary catheters, each having an inner lumen, and each positionable in an inner lumen of the primary catheter to be moveable relatively thereto and exposable therefrom; and a first flexing mechanism to provide a distal end portion of the first and/or second secondary catheter with a tendency to assume a first secondary bent shape. The distal end portion of the first and/or second secondary catheters is provided so as to be able to be flexed by the first flexing mechanism to form an arm portion substantially transverse to the direction of the longitudinal axis of the primary catheter so as to assume the first secondary bent shape when exposed from a distal end portion of the primary catheter.Type: ApplicationFiled: March 2, 2017Publication date: June 22, 2017Applicant: HIGHLIFE SASInventors: Georg BORTLEIN, Malek NASR
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Patent number: 9662206Abstract: A transcatheter atrio-ventricular valve prosthesis for functional replacement of an atrio-ventricular heart valve in a connection channel, the prosthesis comprising a radially expandable tubular body extending along an axis, and a valve arranged within and attached to the tubular body. The tubular body is provided with an outer circumferential groove which is open to the radial outside of the tubular body, whereby the tubular body is separated by the outer circumferential groove into first and second body sections. The tubular body is provided with a first plurality of projections which extend from the first or second body section in an axial direction of the tubular body and each of which has a free end arranged to overlap the outer circumferential groove. An elongate outer member may be disposed at the exterior of the connection channel wall structure at a level of the circumferential groove.Type: GrantFiled: June 13, 2012Date of Patent: May 30, 2017Assignee: HIGHLIFE SASInventors: Georg Börtlein, Malek Nasr
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Patent number: 9387075Abstract: A method for implanting a heart valve includes advancing an elongate outer member from a first delivery catheter to form a loop around native valve leaflets and/or chords of a native valve without substantially occluding the native valve. The method further includes partially deploying from a second delivery catheter a radially self-expandable tubular body having a valve disposed within a lumen of the tubular body, and a preformed groove disposed at an outer surface of the tubular body. The preformed groove extends at least partially around the tubular body, and has a circumferential opening facing radially outward of the tubular body. When the tubular body is partially deployed, the native valve is substantially occluded. Additionally, the method includes moving the loop into the preformed groove after partially deploying the tubular body. The native valve is no longer substantially occluded after fully deploying the tubular body from the second delivery catheter.Type: GrantFiled: March 11, 2014Date of Patent: July 12, 2016Assignee: HIGHLIFE SASInventors: Georg Börtlein, Malek Nasr
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Patent number: 9358108Abstract: A system for implanting a heart valve includes a radially self-expandable tubular body having a preformed groove disposed at an outer surface of the tubular body, and a valve disposed within the tubular body. The preformed groove extends at least partially around the tubular body, and has a circumferential opening facing radially outward. A trapping member is configured to be disposed within the preformed groove on the outer surface of the tubular body and form at least a partial loop around the tubular body. The circumferential opening of the preformed groove is relatively larger when an outflow end of the tubular body has been deployed from a catheter and an inflow end of the tubular body is disposed within the catheter, and the circumferential opening of the preformed groove is relatively smaller when both the outflow end and the inflow end are fully deployed from the catheter.Type: GrantFiled: March 11, 2014Date of Patent: June 7, 2016Assignee: HIGHLIFE SASInventors: Georg Börtlein, Malek Nasr
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Publication number: 20150257879Abstract: A system for implanting a heart valve includes a radially self-expandable tubular body having an inflow end and an outflow end and a preformed groove disposed at an outer surface of the tubular body between the inflow end and the outflow end. The preformed groove extends at least partially around the tubular body, and has a circumferential opening facing radially outward of the tubular body. A valve is disposed within and attached to the tubular body, and a trapping member is configured to be moved into the preformed groove and form at least a partial loop around the preformed groove. An insertion member is configured to push the trapping member into the preformed groove. Additionally, a coupling member can provide a releasable attachment between the trapping member and the insertion member.Type: ApplicationFiled: March 11, 2014Publication date: September 17, 2015Inventors: Georg BÖRTLEIN, Malek NASR
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Publication number: 20150257880Abstract: A system for implanting a heart valve that includes a radially self-expandable tubular body having an inflow end and a preformed groove disposed at an outer surface of the tubular body between the inflow end and the outflow end, wherein the preformed groove extends at least partially around the tubular body and having a circumferential opening facing radially outward of the tubular body. A valve may be disposed within and attached to the tubular body. Additionally, a trapping member may be configured to form at least a partial loop encircling the preformed groove so as to trap portions of native valve leaflets and/or chords in the preformed groove, the trapping member including one or more barbs.Type: ApplicationFiled: March 11, 2014Publication date: September 17, 2015Applicant: HIGHLIFE SASInventors: Georg BÖRTLEIN, Malek NASR
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Publication number: 20150257881Abstract: A system for implanting a heart valve includes a radially self-expandable tubular body having an inflow end and an outflow end, a decorrelation portion, and a preformed groove disposed at an outer surface of the tubular body between the decorrelation portion and the outflow end. The preformed groove extends at least partially around the tubular body, and has a circumferential opening facing radially outward of the tubular body. A valve is disposed within and attached to the tubular body. The decorrelation portion is configured to dissociate axial and radial movements between the inflow end of the tubular body and the outflow end of the tubular body.Type: ApplicationFiled: March 11, 2014Publication date: September 17, 2015Inventors: Georg BÖRTLEIN, Malek NASR
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Publication number: 20150257882Abstract: A system for implanting a heart valve includes a radially self-expandable tubular body having an inflow end and an outflow end and a projection extending from a side surface of the tubular body toward the inflow end. The system further includes a valve disposed within and attached to the tubular body, and may include fabric that forms a pouch between the tubular body and the projection.Type: ApplicationFiled: March 11, 2014Publication date: September 17, 2015Inventors: Georg BÖRTLEIN, Malek NASR
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Publication number: 20150238314Abstract: A treatment catheter system for treatment of a heart valve includes a circumferential valve tissue structure and an elongate catheter member, and and has an inner lumen, proximal and distal end portions. The system includes a catching component which can be positioned at the distal end portion of the catheter member to be non-separable from the catheter member. An outer member extends circumferentially around the catheter member. The circumferential valve tissue structure is correspondingly arranged between the catheter member and the outer member. A catching mechanism reduces a radial distance between the catheter member and the outer member to catch the valve tissue between the outer member and the catheter member via a catching opening to immobilize and treat the caught valve tissue on the distal end portion of the catheter member.Type: ApplicationFiled: September 12, 2012Publication date: August 27, 2015Applicant: HIGHLIFE SASInventors: Georg Börtlein, Malek Nasr
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Patent number: 9066799Abstract: A prosthetic valve assembly for use in replacing a deficient native valve comprises a replacement valve supported on an expandable valve support. If desired, one or more anchor may be used. The valve support, which entirely supports the valve annulus, valve leaflets, and valve commissure points, is configured to be collapsible for transluminal delivery and expandable to contact the anatomical annulus of the native valve when the assembly is properly positioned. The anchor engages the lumen wall when expanded and prevents substantial migration of the valve assembly when positioned in place. The prosthetic valve assembly is compressible about a catheter, and restrained from expanding by an outer sheath. The catheter may be inserted inside a lumen within the body, such as the femoral artery, and delivered to a desired location, such as the heart.Type: GrantFiled: January 20, 2011Date of Patent: June 30, 2015Assignee: MEDTRONIC COREVALVE LLCInventors: Jacques Seguin, Georg Börtlein
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Patent number: RE45865Abstract: A prosthetic valve assembly for use in replacing a deficient native valve comprises a replacement valve supported on an expandable valve support. If desired, one or more anchor may be used. The valve support, which entirely supports the valve annulus, valve leaflets, and valve commissure points, is configured to be collapsible for transluminal delivery and expandable to contact the anatomical annulus of the native valve when the assembly is properly positioned. The anchor engages the lumen wall when expanded and prevents substantial migration of the valve assembly when positioned in place. The prosthetic valve assembly is compressible about a catheter, and restrained from expanding by an outer sheath. The catheter may be inserted inside a lumen within the body, such as the femoral artery, and delivered to a desired location, such as the heart.Type: GrantFiled: August 1, 2014Date of Patent: January 26, 2016Assignee: Medtronic CoreValve LLCInventors: Jacques Seguin, Georg Börtlein