Abstract: A method of measuring fluid properties such as flow velocity, flow rate, and fluid composition comprises positioning a heat exchange element with a temperature sensor, such as an optical fiber temperature sensor, arranged centrally inside the element in thermal contact with a fluid of interest, heating or cooling the heat exchange element to cause a temperature difference and exchange of thermal energy between the element and the fluid, using the temperature sensor to measure the temperature of the heat exchange element during the exchange of thermal energy, and determining properties of the fluid from the temperature measurement. A second temperature sensor can be provided offset from the first sensor to provide additional measurements to improve accuracy, and a plurality of heat exchange elements with temperature sensors can be used together to determine fluid properties over a large region.

Abstract: A distributed temperature sensor is deployed in a wellbore and is functionally connected to a processor. The processor receives the data from the distributed temperature sensor and automatically processes the data to highlight valuable information to the user relating to the relevant well, completion, or reservoir. In one embodiment, the distributed temperature sensor and processor are utilized in a well containing a gas-lift system, wherein the processor highlights valuable information to the user pertaining to the gas-lift system. A well model enabled by the processor enables the determination of a produced fluid flow rate in the well having a gas lift system. Temperatures are measured within the well to obtain a temperature profile, and this profile is processed according to the well model. The well model relates thermal characteristics, e.g. thermal decay and/or amplitude of a thermal discontinuity at an injection point, to flow rate.

Abstract: The invention concerns amide derivatives of the Formula (I) wherein R3 is (1-6C)alkyl or halogeno; Q is aryl or heteroaryl which optionally bears 1, 2, 3 or 4 substituents such as hydroxy, halogeno, trifluoromethyl, cyano, (1-6C)alkyl, (1-6C)alkoxy, halogeno-(1-6C)alkyl, hydroxyl-(1-6C)alkyl, di-[(1-6C)akly]amino-(1-6C)alkyl, hydroxy-(2-6C)alkoxy, (1-6C)alkoxy-(2-6C)alkoxy, di-[(1-6C)alkyl]amino-(2-6C)alkoxy, amino(2-6C)alkylamino, N-(1-6C)alkyl-(1-6C)alkylamino-(2-6C)alkylamino, aryl, aryl-(1-6C)alkoxy, heteroaryl, heteroaryl-(1-6C)alkoxy, heterocyclyl, heterocyclyl-(1-6C)alkyl, heterocyclyloxy and heterocyclyl-(1-6C)alkoxy; p is 0-2 and R2 is a substituent such as hydroxy and halogeno; q is 0-4; and R4 includes optionally substituted aryl, cycloalkyl, heteroaryl and heterocyclyl; or pharmaceutically-acceptable salts or in-vivo-cleavable esters thereof; processes for their preparation, pharmaceutical compositions containing them and their use in the treatment of diseases or medical conditions mediated by cyt

Abstract: A tube assembly (1) comprises a dummy tube (2) formed from extruded medium density polyethylene and five primary tubes (3), also formed from extruded medium density polyethylene, and placed around the dummy tube (2). The primary tubes (3) are also provided with a co-extruded lining (not shown) on the internal surface thereof to minimise static attraction and friction between the tubes (3) and optical fibre units (not shown) subsequently installed into the tubes (3). The tubes (2, 3) and a rip cord (4), for subsequently removing the covering layers of the assembly to gain access to the tubes (2, 3), are surrounded by an outer sheath (5) formed from extruded medium density polyethylene. The outer sheath (5) is provided with a non-metallic water barrier (6), and is surrounded by a lubricant polymer layer (7) containing a polyethylene based lubricant compound, the active constituent of the lubricant being an organic silicone slip agent.

Abstract: A method and apparatus is disclosed for measuring the flow of fluid in the conduit, giving the example of oil in a well bore (12). A heat exchanger such as a cooling station (66) is placed in the well bore (12) and caused to create a slug of cooled oil whose passage, through the well (12) can be monitored by a temperature sensor in the form of a continuous fiber optic loop (62). Knowledge of the movement of the cooled slug of oil and of the free cross-section of the conduit (54) wherein the oil is flowing permits the volume flow-rate of oil to be calculated. Cooling stations (66) are cooled by Joule-Thompson cooling employing high pressure nitrogen gas. Cooling stations (66) may be placed at plural locations within the well bore (12) to monitor individual flows (68) from multiple flow sources.

Abstract: Radiology healthcare providers are trained or evaluated by solving practical patient problems using computer, 3D virtual imaging or manikins associated with software obtained from radiological equipment found in treatment facilities. The software is created from equipment functions and parameters. The trainee dynamically controls the environment and equipment to get results that are compared to expert solutions programmed into the computer.

Abstract: The present invention provides immunocontraceptive vaccines comprising a zona pellucida (ZP) polypeptide, and/or a variant thereof, from a carnivorous mammal such as cat, dog, ferret or mink. Such vaccines are useful in reducing fertility of cats and/or dogs.

Abstract: The present invention is concerned with vaccines and their preparation. An effective long-term immune response, especially in mammals, can be produced using a vaccine comprising an antigen encapsulated in liposomes, a suitable adjuvant and a carrier comprising a continuous phase of a hydrophobic substance. The vaccine is particularly effective in eliciting the production of antibodies that recognize epitopes of native proteins.

Abstract: A system to determine the mixture of fluids in the deviated section of a wellbore comprising at least one distributed temperature sensor adapted to measure the temperature profile along at least two levels of a vertical axis of the deviated section. Each distributed temperature sensor can be a fiber optic line functionally connected to a light source that may utilize optical time domain reflectometry to measure the temperature profile along the length of the fiber line. The temperature profiles at different positions along the vertical axis of the deviated wellbore enables the determination of the cross-sectional distribution of fluids flowing along the deviated section. Together with the fluid velocity of each of the fluids flowing along the deviated section, the cross-sectional fluid distribution enables the calculation of the flow rates of each of the fluids. The system may also be used in conjunction with a pipeline, such as a subsea pipeline, to determine the flow rates of fluids flowing therethrough.

Abstract: A technique usable with a subterranean well includes deploying a first optical sensor downhole in the subterranean well. The technique includes observing an intensity of backscattered light from the first optical sensor to measure a distribution of a characteristic along a portion of the well. The technique includes deploying a second sensor downhole to measure the characteristic at discreet points within the portion. The second sensor is separate from this first sensor and includes at least one interferometric sensor.

Abstract: A technique that usable in a subterranean well includes deploying a first sensor in a remote location to measure a distribution of a characteristic along a segment at the location. The technique includes deploying a second sensor downhole to measure the characteristic at discrete points within the segment. The second sensor is separate from the first sensor.

Abstract: A method and apparatus is disclosed for measuring the flow of fluid in the conduit, giving the example of oil in a well bore (12). A heat exchanger such as a cooling station (66) is placed in the well bore (12) and caused to create a slug of cooled oil whose passage, through the well (12) can be monitored by a temperature sensor in the form of a continuous fiber optic loop (62). Knowledge of the movement of the cooled slug of oil and of the free cross-section of the conduit (54) wherein the oil is flowing permits the volume flow-rate of oil to be calculated. Cooling stations (66) are cooled by Joule-Thompson cooling employing high pressure nitrogen gas. Cooling stations (66) may be placed at plural locations within the well bore (12) to monitor individual flows (68) from multiple flow sources.

Abstract: The present invention is concerned with vaccines and their preparation. An effective long-term immune response, especially in mammals, can be produced using a vaccine comprising an antigen encapsulated in liposomes, a suitable adjuvant and a carrier comprising a continuous phase of a hydrophobic substance. The vaccine is particularly effective in eliciting the production of antibodies that recognize epitopes of native proteins.

Abstract: A broadband cholesteric optical device such as a polarizer or a spectral filter includes a broadband cholesteric layer, for instance, of a graded pitch type such that the cholesteric pitch increases monotonically from one surface of the film to the other surface. In order to improve the off-axis performance, a compensator is provided in the form of a positive birefringence film whose optic axis is substantially perpendicular to the film. Another negative birefringence film whose optic axis is also perpendicular to the film may also be provided.

Abstract: An enhancement of an electrically written memory element utilizing the motion of protons within a dielectric layer surrounded by layers on either side to confine the protons within the dielectric layer with electrode means attached to the surrounding layers to change the spatial position of the protons within the dielectric layer. The device is preferably constructed as a silicon-silicon dioxide-silicon layered structure with the protons being introduced to the structure during an anneal in an atmosphere containing hydrogen gas. Device operation is enhanced by concluding this anneal step with a sudden cooling. The device operates at low power, is preferably nonvolatile, is radiation tolerant, and is compatible with convention silicon MOS processing for integration with other microelectronics elements on the same silicon substrate.

Abstract: An improved footwear closure system and composite liner are provided. The composite liner includes a first component that conforms closely to the upper in the area of the heel, toe and side portions of the upper, and a second, stretchable component that extends across and underneath the area between the split of the upper. The second, stretchable component may form an enlarged fold aligned generally with the centerline of the split of the upper. Both components of the composite liner are preferably constructed from a water-repellant or water-proof, breathable material. The composite liner cooperates with an improved closure system having two complementary strips mounted between the split of the upper and underlying the fasteners. When the closure system is drawn tight, any excess portion of stretchable component is collected between and outside the complementary strips, leaving a smooth surface on the inside of the upper in the area of the split and adjacent the instep.

Abstract: A process for determining one or more leachate concentrations of one or more components of a glass composition in an aqueous solution of the glass composition by identifying the components of the glass composition, including associated oxides, determining a preliminary glass dissolution estimator, .DELTA.G.sub.p, based upon the free energies of hydration for the component reactant species, determining an accelerated glass dissolution function, .DELTA.G.sub.a, based upon the free energy associated with weak acid dissociation, .DELTA.G.sub.a.sup.WA, and accelerated matrix dissolution at high pH, .DELTA.G.sub.a.sup.SB associated with solution strong base formation, and determining a final hydration free energy, .DELTA.G.sub.f. This final hydration free energy is then used to determine leachate concentrations for elements of interest using a regression analysis and the formula log.sub.10 (N C.sub.i (g/L))=a.sub.i +b.sub.i .DELTA.G.sub.f.

Abstract: A correlation processor arrangement is used to guide an airborne vehicle along a path precisely to a predetermined destination. Guidance is divided into three distinct phases, and during each phase the position of the vehicle is verified by matching the view of its surroundings with stored reference data representing the expected fields of view. During the first navigation phase the stored data consists of predetermined terrain areas. During the second detection phase the destination is acquired, and during the third homing phase the view of the approaching destination is used as the stored reference data.

Abstract: A guidance method which enables a moving body to be guided to a predetermined location by allowing the body to view its surroundings and to compare the viewed scene with a reference pattern stored on the body. A number of individual reference patterns are stored, and each reference pattern corresponds to an area of the surroundings which is very much smaller than the field of view and thus the body identifies its position by correlating its field of view with one of the reference patterns. To enable the body to identify its position, even if it deviates from an expected path, a number of reference patterns are laterally displaced from the expected path. The extent of the lateral displacements reduces with decreasing distance from a predetermined location to which the body is to be guided.

Abstract: Laser light reflected from a bar code symbol pattern is detected by a photodetector mounted in a portable scanning head of a laser scanning system. By selecting appropriate threshold values on the analog signal generated by the photodetector, the analog signal is converted to a series of pulses, each pulse width accurately corresponding to the width of a bar from the scanned pattern. A plurality of functions can be determined from the series of pulses, each function being independently selected by keyboard entry from the head, displayed on the head, and/or recorded by a printer remote from the head. Single line or multiple line scans in two orthogonal directions relative to the pattern may be selected. A bimorph or speaker-type oscillatory element may be utilized as a miniature scanning element. Circuitry for synchronizing scanning along both axes, and for generating a signal to drive the bimorph in a uniform, constant velocity manner is also disclosed.