Patents by Inventor George A. Haas
George A. Haas has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 4144488Abstract: An electron-beam scanning system for investigating the nonuniformity of (1) he work function, (2) the position of the conduction-band edge with respect to the Fermi level, and (3) the electron affinity at the surface of a single-crystal semiconductor. A small-diameter, low-energy electron beam is scanned over the surface to be investigated. The current collected by the surface for electron energies in the retarding-field region is related to the work function of the surface, whereas the current collected by the surface for electron energies in the accelerating-field region is related to the position of the conduction-band edge. The electron affinity is related to the combination of these relationships. Variations in the current collected by the surface for appropriately selected electron energies are used to provide a visual display of variations in these quantities.Type: GrantFiled: December 22, 1977Date of Patent: March 13, 1979Assignee: The United States of America as represented by the Secretary of the NavyInventors: George A. Haas, Arnold Shih, Richard E. Thomas
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Patent number: 4142145Abstract: A method which utilizes low-energy electron reflections to determine the ctron affinity and to simultaneously locate the position of the conduction-band edge with respect to the Fermi level at the surface of a single-crystal semiconductor. A beam of very-low-energy electrons (<10eV) is directed onto the surface of the semiconductor and the reflection pattern (beam energy v. current collected by the semiconductor) is analyzed using a kinematical approximation for the interference phenomena.Type: GrantFiled: December 22, 1977Date of Patent: February 27, 1979Assignee: The United States of America as represented by the Secretary of the NavyInventors: George A. Haas, Arnold Shih, Richard E. Thomas
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Patent number: 4112099Abstract: New pyridine compounds of the general formula I ##STR1## wherein R denotes an optionally substituted cycloaliphatic hydrocarbon radical, Ph denotes an ortho-phenylene radical or especially a para-phenylene radical, A denotes a lower alkylene radical or a direct bond, X denotes an optionally functionally modified oxo group and Py denotes a pyridine radical, are useful as fibrinolytics, thrombolytics, antiphlogistics and as mild analgesics.Type: GrantFiled: April 28, 1976Date of Patent: September 5, 1978Assignee: Ciba-Geigy CorporationInventors: Georges Haas, Alberto Rossi
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Patent number: 4076822Abstract: New pyridine compounds of the general formula I ##STR1## wherein R denotes an optionally substituted cycloaliphatic hydrocarbon radical, Ph denotes an ortho-phenylene radical or especially a para-phenylene radical, A denotes a lower alkylene radical or a direct bond, X denotes an optionally functionally modified oxo group and Py denotes a pyridine radical, are useful as fibrinolytics, thrombolytics, antiphlogistics and as mild analgesics.Type: GrantFiled: April 28, 1976Date of Patent: February 28, 1978Assignee: Ciba-Geigy CorporationInventors: Georges Haas, Alberto Rossi
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Patent number: 4057573Abstract: Compounds of the general formula I ##STR1## wherein one of the two radicals R.sub.1 and R.sub.2 denotes the acyl radical of a carboxylic acid of aromatic character and the other denotes hydrogen or optionally esterified or etherified hydroxyl, R.sub.3 denotes hydrogen, alkyl or hydroxyalkyl, R.sub.4 denotes optionally esterified or amidised carboxyl, m denotes 1 or 2 and n denotes 0 or 1, in the free form or in the form of their salts are useful as antiphlogistics, mild analgesics, antipyretics and as anti-rheumatic agents.Type: GrantFiled: February 11, 1975Date of Patent: November 8, 1977Assignee: Ciba-Geigy CorporationInventors: Georges Haas, Alberto Rossi
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Patent number: 4035413Abstract: Compounds of the formula Ir.sub.1 -- ph -- X -- alk -- R.sub.2 (I)wherein R.sub.1 is adamantyl, Ph is phenylene which is optionally substituted by amino, nitro, lower alkyl, lower alkoxy, halogen or trifluoromethyl, X is oxy or thio, alk is alkylene with 1 to 20 C atoms or alkenylene with 2 to 20 C atoms and R.sub.2 is free, esterified or amidized carboxyl, sulpho or sulphonamido and therapeutically acceptable salts thereof are useful as anti-allergic and hypolipidaemic agents.Type: GrantFiled: August 18, 1975Date of Patent: July 12, 1977Assignee: Ciba-Geigy CorporationInventors: Georges Haas, Roland Jaques, Alberto Rossi, Martin Ruegg
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Patent number: 4013708Abstract: New compounds of the general formula Ir.sub.1 -- ph -- X -- CR.sub.2 R.sub.4 -- alk -- R.sub.3 (I)wherein R.sub.1 denotes a cycloalkenyl radical or a monocyclic cycloalkyl radical, Ph denotes an optionally substituted phenylene radical, X denotes the oxy or thio group, R.sub.2 denotes hydrogen or alkyl, R.sub.3 denotes an optionally functionally modified carboxyl group, a sulpho group or a sulphamido group, alk denotes an alkylene or alkenylene radical which separates the groups R.sub.1 --Ph--X--CR.sub.2 R.sub.4 and R.sub.3 by at least 2 carbon atoms and R.sub.4 is hydrogen or, if alk separates the groups R.sub.1 --Ph--X--CR.sub.2 R.sub.4 and R.sub.3 by at least 3 carbon atoms or R.sub.1 denotes a cycloalkenyl radical, R.sub.4 can also denote alkyl, in the free form or in the form of salts are useful as antiallergics.Type: GrantFiled: September 11, 1974Date of Patent: March 22, 1977Assignee: Ciba-Geigy CorporationInventors: Georges Haas, Pier Giorgio Ferrini, Alberto Rossi
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Patent number: 4013719Abstract: Compounds of the formula Ir.sub.1 -- ph -- X -- alk -- R.sub.2 (I)wherein R.sub.1 is adamantyl, Ph is phenylene which is optionally substituted by, nitro, lower alkyl, lower alkoxy, halogen or trifluoromethyl, X is oxy or thio, alk is alkylene with 1 to 20 C atoms or alkenylene with 2 to 20 C atoms and R.sub.2 is free, esterified or amidised carboxyl, sulpho or sulphonamido and therapeutically acceptable salts thereof are useful as anti-allergic and hypolipidaemic agents.Type: GrantFiled: August 18, 1975Date of Patent: March 22, 1977Assignee: Ciba-Geigy CorporationInventors: Georges Haas, Roland Jaques, Alberto Rossi, Martin Ruegg
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Patent number: 4004026Abstract: Benzocycloalkenderivatives substituted in 1-position by carboxyl and carboxyalkyl or two carboxyl groups, and further substituted in the benzene ring by cycloalkyl and optionally other substituents, their esters, amides and pharmaceutically acceptable salts have antiinflammatory and analgesic activity and can be used for the treatment of inflammatory conditions and pain in mammals; a representative embodiment is 1-methoxycarbonyl-5-cyclohexyl-6-chloro-1-indanecarboxylic acid.Type: GrantFiled: November 18, 1975Date of Patent: January 18, 1977Assignee: Ciba-Geigy CorporationInventors: Georges Haas, Erwin F. Jenny, Alberto Rossi
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Patent number: 4000144Abstract: Compounds of the formula Ir.sub.1 - ph - X - alk - R.sub.2 (I)wherein R.sub.1 is adamantyl, Ph is phenylene which is optionally substituted by amino, nitro, lower alkyl, lower alkoxy, halogen or trifluoromethyl, X is oxy or thio, alk is alkylene with 1 to 20 C atoms or alkenylene with 2 to 20 C atoms and R.sub.2 is free, esterified or amidised carboxyl, sulpho or sulphonamido and therapeutically acceptable salts thereof are useful as anti-allergic and hypolipidaemic agents.Type: GrantFiled: August 18, 1975Date of Patent: December 28, 1976Assignee: Ciba-Geigy CorporationInventors: Georges Haas, Roland Jaques, Alberto Rossi, Martin Ruegg
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Patent number: 4000183Abstract: Compounds of the formula Ir.sub.1 -- ph -- X -- alk -- R.sub.2 (I)wherein R.sub.1 is adamantyl, Ph is phenylene which is optionally substituted by amino, nitro, lower alkyl, lower alkoxy, halogen or trifluoromethyl, X is oxy or thio, alk is alkylene with 1 to 20 C atoms or alkenylene with 2 to 20 C atoms and R.sub.2 is free, esterified or amidised carboxyl, sulpho or sulphonamido and therapeutically acceptable salts thereof are useful as anti-allergic and hypolipidaemic agents.Type: GrantFiled: August 18, 1975Date of Patent: December 28, 1976Assignee: Ciba-Geigy CorporationInventors: Georges Haas, Roland Jaques, Alberto Rossi, Martin Ruegg
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Patent number: 3980657Abstract: New pyridine compounds of the general formula I ##EQU1## wherein R denotes an optionally substituted cycloaliphatic hydrocarbon radical, Ph denotes an ortho-phenylene radical or especially a para-phenylene radical, A denotes a lower alkylene radical or a direct bond, X denotes an optionally functionally modified oxo group and Py denotes a pyridine radical, are useful as fibrinolytics, thrombolytics, antiphlogistics and as mild analgesics.Type: GrantFiled: February 19, 1974Date of Patent: September 14, 1976Assignee: Ciba-Geigy CorporationInventors: Georges Haas, Alberto Rossi
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Patent number: 3973024Abstract: Basic esters and acid addition salts thereof of substituted o-anilino-phenylacetic acids with pyridinols or pyridine-alkanols have anti-inflammatory and analgesic activity; they are active ingredients of pharmaceutical compositions and can be used for the relief and removal of pain as well as for the treatment of rheumatic, arthritic and other inflammatory complaints; an illustrative example is [o-(2,6-Dichloro-anilino)-phenyl]-acetic acid (2-pyridyl)-methyl ester.Type: GrantFiled: April 28, 1975Date of Patent: August 3, 1976Assignee: Ciba-Geigy CorporationInventors: Georges Haas, Alfred Sallmann
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Patent number: 3971110Abstract: An improved technique for forming an electron emitting cathode of iridium d similar noble metals. A mixture of powders including a matrix material of one of the noble metals and a pore forming material of silver is shaped into a cathode configuration and sintered at a temperature sufficient to evaporate the silver, thereby producing a porous matrix. The matrix is impregnated with an active material and dried to produce a cathode having increased electron emission characteristics allowing operation at lower temperatures for longer time periods.Type: GrantFiled: September 11, 1975Date of Patent: July 27, 1976Assignee: The United States of America as represented by the Secretary of the NavyInventors: Richard E. Thomas, George A. Haas
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Patent number: 3960868Abstract: wherein Ph denotes a 1,2-phenylene radical which carries cycloaliphatic radical, R.sub.x denotes a free or etherified hydroxyl group or a free or substituted amino group, R.sub.o denotes an alkyl radical, a free hydroxyl group or a hydroxyl group etherified by lower alkyl or, above all, a hydrogen atom and R.sub.1 denotes an aliphatic or cycloaliphatic hydrocarbon radical which is optionally substituted by hydroxyl, an araliphatic radical or a hydrogen atom, and their salts, which possess valuable analgesic, anti-inflammatory, anti-microbial and histamine liberation inhibiting properties.Type: GrantFiled: May 6, 1974Date of Patent: June 1, 1976Assignee: Ciba-Geigy CorporationInventors: Pier Giorgio Ferrini, Georges Haas, Alberto Rossi
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Patent number: 3940434Abstract: Benzocycloalkenderivatives substituted in 1-position by carboxyl and carboxyalkyl or two carboxyl groups, and further substituted in the benzene ring by cycloalkyl and optionally other substituents, their esters, amides and pharmaceutically acceptable salts have antiinflammatory and analgesic activity and can be used for the treatment of inflammatory conditions and pain in mammals; a representative embodiment is 1-methoxycarbonyl-5-cyclohexyl-6-chloro-1-indanecarboxylic acid.Type: GrantFiled: August 16, 1973Date of Patent: February 24, 1976Assignee: Ciba-Geigy CorporationInventors: Georges Haas, Erwin F. Jenny, Alberto Rossi
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Patent number: 3933835Abstract: Compounds of the formula IR.sub.1 -- Ph -- X -- alk -- R.sub.2 (I)wherein R.sub.1 is adamantyl, Ph is phenylene which is optionally substituted by amino, nitro, lower alkyl, lower alkoxy, halogen or trifluoromethyl, X is oxy or thio, alk is alkylene with 1 to 20 C atoms or alkenylene with 2 to 20 C atoms and R.sub.2 is free, esterfied or amidised carboxyl, sulpho or sulphonamido and therapeutically acceptable salts thereof are useful as anti-allergic and hypolipidaemic agents.Type: GrantFiled: October 24, 1973Date of Patent: January 20, 1976Assignee: Ciba-Geigy CorporationInventors: Georges Haas, Roland Jaques, Alberto Rossi, Martin Ruegg
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Patent number: 3933802Abstract: New 2-amino-5-sulphamoylbenzoic acid amide of the general formula ##SPC1##Wherein R.sub.1 denotes lower alkyl, R.sub.2 denotes hydrogen, halogen, trifluoromethyl, lower alkyl or lower alkoxy, R.sub.3 denotes hydrogen, hydroxyl or lower alkyl, R.sub.4 denotes acyl and alk denotes lower 1,2-alkylene or 1,3-alkylene or a therapeutically acceptable acid addition salt thereof are usefull as mild analgesics with an anti-inflammatory component of action.Type: GrantFiled: May 22, 1974Date of Patent: January 20, 1976Assignee: Ciba-Geigy CorporationInventors: Pier Giorgio Ferrini, Georges Haas, Alberto Rossi