Patents by Inventor George Bakis
George Bakis has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20230301782Abstract: The present disclosure is directed to embodiments of catheter-based prosthetic heart valves. In one embodiment, a prosthetic heart valve includes a collapsible and expandable annular frame, a leaflet assembly mounted within the annular frame, a first skirt mounted on the frame, and a second skirt mounted on the frame. The frame includes a plurality of rows of cells. The leaflet assembly includes a plurality of leaflets. Adjacent leaflets are connected to each other to form commissures, each of which is connected to a cell of an outflow row of cells of the frame. Inflow end portions of the leaflets are sutured to an outflow end portion of the first skirt along undulating suture line.Type: ApplicationFiled: May 26, 2023Publication date: September 28, 2023Inventors: Alexander J. Siegel, George Bakis
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Publication number: 20220211497Abstract: A two-stage or component-based valve prosthesis that can be quickly and easily implanted during a surgical procedure is provided. The prosthetic valve comprises a support structure that is deployed at a treatment site. The prosthetic valve further comprises a valve member configured to be quickly connected to the support structure. The support structure may take the form of a stent that is expanded at the site of a native valve. If desired, the native leaflets may remain and the stent may be used to hold the native valve open. In this case, the stent may be balloon expandable and configured to resist the powerful recoil force of the native leaflets. The support structure is provided with a coupling means for attachment to the valve member, thereby fixing the position of the valve member in the body. The valve member may be a non-expandable type, or may be expandable from a compressed state to an expanded state.Type: ApplicationFiled: March 25, 2022Publication date: July 7, 2022Applicant: Edwards Lifesciences CorporationInventors: Stanton J. Rowe, Larry L. Wood, Henry Bourang, George Bakis, Benjamin Spenser, Netanel Benichou, Assaf Bash, Yaron Keidar
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Patent number: 11284998Abstract: A two-stage or component-based valve prosthesis that can be quickly and easily implanted during a surgical procedure is provided. The prosthetic valve comprises a support structure that is deployed at a treatment site. The prosthetic valve further comprises a valve member configured to be quickly connected to the support structure. The support structure may take the form of a stent that is expanded at the site of a native valve. If desired, the native leaflets may remain and the stent may be used to hold the native valve open. In this case, the stent may be balloon expandable and configured to resist the powerful recoil force of the native leaflets. The support structure is provided with a coupling means for attachment to the valve member, thereby fixing the position of the valve member in the body. The valve member may be a non-expandable type, or may be expandable from a compressed state to an expanded state.Type: GrantFiled: October 28, 2019Date of Patent: March 29, 2022Assignee: Edwards Lifesciences CorporationInventors: Stanton J. Rowe, Larry L. Wood, Henry Bourang, George Bakis, Benjamin Spenser, Netanel Benichou, Assaf Bash, Yaron Keidar
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Publication number: 20200306037Abstract: The present disclosure is directed to embodiments of catheter-based prosthetic heart valves, and in particular, prosthetic heart valves having sealing members configured to seal the interface between the prosthetic valve and the surrounding tissue of the native annulus in which the prosthetic valve is implanted. In one embodiment, a prosthetic heart valve includes a collapsible and expandable annular frame, a collapsible and expandable valve member mounted within the annular frame, and a collapsible and expandable sealing skirt mounted on the annular frame, wherein the sealing skirt is a pile fabric and can contact tissue surrounding the prosthetic valve when the prosthetic valve is implanted within a native valve annulus.Type: ApplicationFiled: June 16, 2020Publication date: October 1, 2020Inventors: Alexander J. Siegel, George Bakis
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Publication number: 20200297487Abstract: Certain embodiments of the present disclosure provide a prosthetic valve (e.g., prosthetic heart valve) and a valve delivery apparatus for delivery of the prosthetic valve to a native valve site via the human vasculature. The delivery apparatus is particularly suited for advancing a prosthetic heart valve through the aorta (i.e., in a retrograde approach) for replacing a diseased native aortic valve. The delivery apparatus in particular embodiments is configured to deploy a prosthetic valve from a delivery sheath in a precise and controlled manner at the target location within the body.Type: ApplicationFiled: June 9, 2020Publication date: September 24, 2020Inventors: George Bakis, Thanh V. Nguyen, Ly Th Phan, Asher L. Metchik
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Publication number: 20200237508Abstract: The present disclosure pertains to introducer sheaths with an inner liner for percutaneous insertion of a medical device into a patient. The introducer sheaths can further have a tubular layer and an outer layer. The tubular layer can be a metal sleeve having a plurality of slots. The present disclosure also discloses embodiments of catheter-based prosthetic heart valves, including, prosthetic heart valves having sealing members configured to seal the interface between the prosthetic valve and the surrounding tissue of the native annulus in which the prosthetic valve is implanted.Type: ApplicationFiled: March 23, 2020Publication date: July 30, 2020Inventors: Alexander J. Siegel, George Bakis
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Patent number: 10695176Abstract: Certain embodiments of the present disclosure provide a prosthetic valve (e.g., prosthetic heart valve) and a valve delivery apparatus for delivery of the prosthetic valve to a native valve site via the human vasculature. The delivery apparatus is particularly suited for advancing a prosthetic heart valve through the aorta (i.e., in a retrograde approach) for replacing a diseased native aortic valve. The delivery apparatus in particular embodiments is configured to deploy a prosthetic valve from a delivery sheath in a precise and controlled manner at the target location within the body.Type: GrantFiled: January 11, 2018Date of Patent: June 30, 2020Assignee: Edwards Lifesciences CorporationInventors: George Bakis, Thanh V. Nguyen, Ly Th Phan, Asher L. Metchik
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Patent number: 10595993Abstract: The present disclosure pertains to new methods of making an introducer sheath with an inner liner for percutaneous insertion of a medical device into a patient. The present disclosure also discloses embodiments of catheter-based prosthetic heart valves, including, prosthetic heart valves having sealing members configured to seal the interface between the prosthetic valve and the surrounding tissue of the native annulus in which the prosthetic valve is implanted.Type: GrantFiled: October 2, 2018Date of Patent: March 24, 2020Assignee: Edwards Lifesciences CorporationInventors: Alexander J. Siegel, George Bakis
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Publication number: 20200054450Abstract: A two-stage or component-based valve prosthesis that can be quickly and easily implanted during a surgical procedure is provided. The prosthetic valve comprises a support structure that is deployed at a treatment site. The prosthetic valve further comprises a valve member configured to be quickly connected to the support structure. The support structure may take the form of a stent that is expanded at the site of a native valve. If desired, the native leaflets may remain and the stent may be used to hold the native valve open. In this case, the stent may be balloon expandable and configured to resist the powerful recoil force of the native leaflets. The support structure is provided with a coupling means for attachment to the valve member, thereby fixing the position of the valve member in the body. The valve member may be a non-expandable type, or may be expandable from a compressed state to an expanded state.Type: ApplicationFiled: October 28, 2019Publication date: February 20, 2020Inventors: Stanton J. Rowe, Larry L. Wood, Henry Bourang, George Bakis, Benjamin Spenser, Netanel Benichou, Assaf Bash, Yaron Keidar
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Patent number: 10456251Abstract: A two-stage or component-based valve prosthesis that can be quickly and easily implanted during a surgical procedure is provided. The prosthetic valve comprises a support structure that is deployed at a treatment site. The prosthetic valve further comprises a valve member configured to be quickly connected to the support structure. The support structure may take the form of a stent that is expanded at the site of a native valve. If desired, the native leaflets may remain and the stent may be used to hold the native valve open. In this case, the stent may be balloon expandable and configured to resist the powerful recoil force of the native leaflets. The support structure is provided with a coupling means for attachment to the valve member, thereby fixing the position of the valve member in the body. The valve member may be a non-expandable type, or may be expandable from a compressed state to an expanded state.Type: GrantFiled: March 11, 2019Date of Patent: October 29, 2019Assignee: Edwards Lifesciences CorporationInventors: Stanton J. Rowe, Larry L. Wood, Henry Bourang, George Bakis, Benjamin Spenser, Netanel Benichou, Assaf Bash, Yaron Keidar
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Publication number: 20190201195Abstract: A two-stage or component-based valve prosthesis that can be quickly and easily implanted during a surgical procedure is provided. The prosthetic valve comprises a support structure that is deployed at a treatment site. The prosthetic valve further comprises a valve member configured to be quickly connected to the support structure. The support structure may take the form of a stent that is expanded at the site of a native valve. If desired, the native leaflets may remain and the stent may be used to hold the native valve open. In this case, the stent may be balloon expandable and configured to resist the powerful recoil force of the native leaflets. The support structure is provided with a coupling means for attachment to the valve member, thereby fixing the position of the valve member in the body. The valve member may be a non-expandable type, or may be expandable from a compressed state to an expanded state.Type: ApplicationFiled: March 11, 2019Publication date: July 4, 2019Inventors: Stanton J. Rowe, Larry L. Wood, Henry Bourang, George Bakis, Benjamin Spenser, Netanel Benichou, Assaf Bash, Yaron Keidar
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Publication number: 20190091017Abstract: A two-stage or component-based valve prosthesis that can be quickly and easily implanted during a surgical procedure is provided. The prosthetic valve comprises a support structure that is deployed at a treatment site. The prosthetic valve further comprises a valve member configured to be quickly connected to the support structure. The support structure may take the form of a stent that is expanded at the site of a native valve. If desired, the native leaflets may remain and the stent may be used to hold the native valve open. In this case, the stent may be balloon expandable and configured to resist the powerful recoil force of the native leaflets. The support structure is provided with a coupling means for attachment to the valve member, thereby fixing the position of the valve member in the body. The valve member may be a non-expandable type, or may be expandable from a compressed state to an expanded state.Type: ApplicationFiled: November 20, 2018Publication date: March 28, 2019Applicant: Edwards Lifesciences CorporationInventors: Stanton J. Rowe, Larry L. Wood, Henry Bourang, George Bakis, Benjamin Spenser, Netanel Benichou, Assaf Bash, Yaron Keidar
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Patent number: 10226338Abstract: A two-stage or component-based valve prosthesis that can be quickly and easily implanted during a surgical procedure is provided. The prosthetic valve comprises a support structure that is deployed at a treatment site. The prosthetic valve further comprises a valve member configured to be quickly connected to the support structure. The support structure may take the form of a stent that is expanded at the site of a native valve. If desired, the native leaflets may remain and the stent may be used to hold the native valve open. In this case, the stent may be balloon expandable and configured to resist the powerful recoil force of the native leaflets. The support structure is provided with a coupling means for attachment to the valve member, thereby fixing the position of the valve member in the body. The valve member may be a non-expandable type, or may be expandable from a compressed state to an expanded state.Type: GrantFiled: November 20, 2018Date of Patent: March 12, 2019Assignee: Edwards Lifesciences CorporationInventors: Stanton J. Rowe, Larry L. Wood, Henry Bourang, George Bakis, Benjamin Spenser, Netanel Benichou, Assaf Bash, Yaron Keidar
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Publication number: 20190029818Abstract: The present disclosure pertains to new methods of making an introducer sheath with an inner liner for percutaneous insertion of a medical device into a patient. The present disclosure also discloses embodiments of catheter-based prosthetic heart valves, including, prosthetic heart valves having sealing members configured to seal the interface between the prosthetic valve and the surrounding tissue of the native annulus in which the prosthetic valve is implanted.Type: ApplicationFiled: October 2, 2018Publication date: January 31, 2019Inventors: Alexander J. Siegel, George Bakis
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Patent number: 10130468Abstract: A two-stage or component-based valve prosthesis that can be quickly and easily implanted during a surgical procedure is provided. The prosthetic valve comprises a support structure that is deployed at a treatment site. The prosthetic valve further comprises a valve member configured to be quickly connected to the support structure. The support structure may take the form of a stent that is expanded at the site of a native valve. If desired, the native leaflets may remain and the stent may be used to hold the native valve open. In this case, the stent may be balloon expandable and configured to resist the powerful recoil force of the native leaflets. The support structure is provided with a coupling means for attachment to the valve member, thereby fixing the position of the valve member in the body. The valve member may be a non-expandable type, or may be expandable from a compressed state to an expanded state.Type: GrantFiled: January 11, 2017Date of Patent: November 20, 2018Assignee: EDWARDS LIFESCIENCES CORPORATIONInventors: Stanton J. Rowe, Larry L. Wood, Henry Bourang, George Bakis, Benjamin Spenser, Netanel Benichou, Assaf Bash, Yaron Keidar
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Publication number: 20180125656Abstract: Certain embodiments of the present disclosure provide a prosthetic valve (e.g., prosthetic heart valve) and a valve delivery apparatus for delivery of the prosthetic valve to a native valve site via the human vasculature. The delivery apparatus is particularly suited for advancing a prosthetic heart valve through the aorta (i.e., in a retrograde approach) for replacing a diseased native aortic valve. The delivery apparatus in particular embodiments is configured to deploy a prosthetic valve from a delivery sheath in a precise and controlled manner at the target location within the body.Type: ApplicationFiled: January 11, 2018Publication date: May 10, 2018Inventors: George Bakis, Thanh V. Nguyen, Ly Th Phan, Asher L. Metchik
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Patent number: 9867700Abstract: Certain embodiments of the present disclosure provide a prosthetic valve (e.g., prosthetic heart valve) and a valve delivery apparatus for delivery of the prosthetic valve to a native valve site via the human vasculature. The delivery apparatus is particularly suited for advancing a prosthetic heart valve through the aorta (i.e., in a retrograde approach) for replacing a diseased native aortic valve. The delivery apparatus in particular embodiments is configured to deploy a prosthetic valve from a delivery sheath in a precise and controlled manner at the target location within the body.Type: GrantFiled: May 20, 2014Date of Patent: January 16, 2018Assignee: Edwards Lifesciences CorporationInventors: George Bakis, Thanh V. Nguyen, Ly T. Phan, Asher L. Metchik
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Publication number: 20170119525Abstract: A two-stage or component-based valve prosthesis that can be quickly and easily implanted during a surgical procedure is provided. The prosthetic valve comprises a support structure that is deployed at a treatment site. The prosthetic valve further comprises a valve member configured to be quickly connected to the support structure. The support structure may take the form of a stent that is expanded at the site of a native valve. If desired, the native leaflets may remain and the stent may be used to hold the native valve open. In this case, the stent may be balloon expandable and configured to resist the powerful recoil force of the native leaflets. The support structure is provided with a coupling means for attachment to the valve member, thereby fixing the position of the valve member in the body. The valve member may be a non-expandable type, or may be expandable from a compressed state to an expanded state.Type: ApplicationFiled: January 11, 2017Publication date: May 4, 2017Inventors: Stanton J. Rowe, Larry L. Wood, Henry Bourang, George Bakis, Benjamin Spenser, Netanel Benichou, Assaf Bash, Yaron Keidar
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Patent number: 9554903Abstract: A heart valve prosthesis that can be quickly and easily implanted during a surgical procedure is provided. The prosthetic valve comprises a support structure that is deployed at a treatment site. The prosthetic valve further comprises a valve member configured to be quickly connected to the support structure. The support structure may take the form of a stent that is expanded at the site of a native valve. If desired, the native leaflets may remain and the stent may be used to hold the native valve open. In this case, the stent may be balloon expandable and configured to resist the powerful recoil force of the native leaflets. The support structure is provided with a coupling means for attachment to the valve member, thereby fixing the position of the valve member in the body. The valve member may be expandable or a non-expandable type.Type: GrantFiled: December 15, 2014Date of Patent: January 31, 2017Assignee: Edwards Lifesciences CorporationInventors: Stanton J. Rowe, Larry L. Wood, Henry Bourang, George Bakis, Benjamin Spenser, Netanel Benichou, Assaf Bash, Yaron Keidar
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Publication number: 20150157455Abstract: The present disclosure is directed to embodiments of catheter-based prosthetic heart valves, and in particular, prosthetic heart valves having sealing members configured to seal the interface between the prosthetic valve and the surrounding tissue of the native annulus in which the prosthetic valve is implanted. The present disclosure also discloses new methods of making an introducer sheath with an inner liner for percutaneous insertion of a medical device into a patient.Type: ApplicationFiled: December 4, 2014Publication date: June 11, 2015Applicant: Edwards Lifesciences CorporationInventors: Lien-Huong T. Hoang, Alexander J. Siegel, George Bakis