Patents by Inventor George D. Wilner

George D. Wilner has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Anticoagulant therapy
    Patent number: 4885277
    Abstract: A composition and method for treating thrombotic disorders. The composition comprises a peptide comprising an amino acid sequence corresponding to the sequence of the amino acid residues in the EGF domain of Factor IX, or a subsequence thereof. Such peptides compete with coagulation Factors IX and IXa for endothelial binding cites and thereby inhibit thrombosis formation.
    Type: Grant
    Filed: November 6, 1987
    Date of Patent: December 5, 1989
    Assignee: Oklahoma Medical Research Foundation
    Inventors: Peter P. Nawroth, David M. Stern, George D. Wilner
  • Mitogenic peptides
    Patent number: 4704451
    Abstract: Novel tetradecapeptides having the following sequence were found to have potent mitogenic activity for machropage-like cells:H-Tyr-Pro-Pro-X-Asn-Lys-Asn-Phe-Thr-Glu-Asn-Asp-Leu-Leu-OH,wherein X=Trp or Tyr,or the physiologically acceptable salts, esters or amides thereof.
    Type: Grant
    Filed: October 15, 1985
    Date of Patent: November 3, 1987
    Assignee: Washington University
    Inventor: George D. Wilner
  • Method of stimulating the growth of macrophage-like cells utilizing mitogenic peptides
    Patent number: 4704380
    Abstract: Novel tetradecapeptides having the following sequence were found to have potent mitogenic activity for machropage-like cells:H-Tyr-Pro-Pro-X-Asn-Lys-Asn-Phe-Thr-Glu-Asn-Asp-Leu-Leu-OH,wherein X=Trp or Tyr, or the physiologically acceptable salts, esters or amides thereof.
    Type: Grant
    Filed: January 7, 1987
    Date of Patent: November 3, 1987
    Assignee: Washington University
    Inventor: George D. Wilner