Patents by Inventor George Eisenbarth

George Eisenbarth has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Therapeutic compositions and methods for the prevention of autoimmune diseases
    Patent number: 8673300
    Abstract: Antibodies specific for an MHC class II-autoantigen complex.
    Type: Grant
    Filed: June 3, 2010
    Date of Patent: March 18, 2014
    Assignees: The Regents of the University of Colorado, a body corporate, National Jewish Health
    Inventors: George Eisenbarth, Li Zhang, John Kappler, Brian Stadinski
  • COMPOUNDS THAT MODULATE AUTOIMMUNITY AND METHODS OF USING THE SAME
    Publication number: 20120195929
    Abstract: The invention provides methods of preventing, treating or ameliorating autoimmune diseases such as diabetes by modulating the binding of MHC class II molecules to antigenic peptides or fragments of antigenic peptides of the autoimmune disease by the administration of small organic compounds. The invention also provides pharmaceutical compositions comprising the therapeutically effective small organic compounds and methods of using the same.
    Type: Application
    Filed: June 4, 2010
    Publication date: August 2, 2012
    Inventors: George Eisenbarth, Aaron Michels, David Ostrov, Maki Nakayama
  • THERAPEUTIC COMPOSITIONS AND METHODS FOR THE PREVENTION OF AUTOIMMUNE DISEASES
    Publication number: 20120171212
    Abstract: The present invention is directed to therapeutic compositions and methods for the prevention or treatment of autoimmune diseases, comprising molecules that disrupt or prevent the assembly of the trimolecular complex required for the T cell immune response comprising the autoantigen, the MHC class II molecule, and the T cell receptor implicated in the autoimmune disease.
    Type: Application
    Filed: June 3, 2010
    Publication date: July 5, 2012
    Inventors: George Eisenbarth, Li Zhang, John Kappler, Brian Stadinski
  • Method of treating or preventing Type 1 diabetes by oral administration of insulin
    Patent number: 6703361
    Abstract: Disclosed herein are methods for treating or preventing a disease in mammals having the characteristics of Type 1 diabetes comprising administering insulin or disease suppressive fragments of insulin or analogs thereof in oral or aerosol dosage forms to said mammals. Also disclosed herein are pharmaceutical formulation or dosage forms for use in the methods.
    Type: Grant
    Filed: December 2, 1998
    Date of Patent: March 9, 2004
    Assignee: AutoImmune Inc.
    Inventors: Howard L. Weiner, George Eisenbarth, David Allen Hafler, Zhengyi Zhang
  • METHOD OF TREATING OR PREVENTING TYPE 1 DIABETES BY ORAL ADMINISTRATION OF INSULIN
    Publication number: 20010056063
    Abstract: Disclosed herein are methods for treating or preventing a disease in mammals having the characteristics of Type 1 diabetes comprising administering insulin or disease suppressive fragments of insulin or analogs thereof in oral or aerosol dosage forms to said mammals. Also disclosed herein are pharmaceutical formulation or dosage forms for use in the methods.
    Type: Application
    Filed: December 2, 1998
    Publication date: December 27, 2001
    Inventors: HOWARD L. WEINER, GEORGE EISENBARTH, DAVID ALLEN HAFLER, ZENGYI ZHANG
  • Method of treating or preventing Type 1 diabetes by oral administration of insulin
    Patent number: 5843886
    Abstract: Disclosed herein are methods for treating or preventing a disease in mammals having the characteristics of Type 1 diabetes comprising administering insulin or disease suppressive fragments of insulin or analogs thereof in oral or aerosol dosage forms to said mammals. Also disclosed herein are pharmaceutical formulation or dosage forms for use in the methods.
    Type: Grant
    Filed: June 2, 1995
    Date of Patent: December 1, 1998
    Assignee: Autoimmune, Inc.
    Inventors: Howard L. Weiner, George Eisenbarth, David Allen Hafler, Zhengi Zhang
  • Method of treating or preventing type 1 diabetes by oral administration of insulin
    Patent number: 5643868
    Abstract: Disclosed herein are methods for treating or preventing a disease in mammals having the characteristics of Type 1 diabetes comprising administering insulin or disease suppressive fragments of insulin or analogs thereof in oral or aerosol dosage forms to said mammals. Also disclosed herein are pharmaceutical formulation or dosage forms for use in the methods.
    Type: Grant
    Filed: June 6, 1995
    Date of Patent: July 1, 1997
    Assignee: Autoimmune, Inc.
    Inventors: Howard L. Weiner, George Eisenbarth, David Allen Hafler, Zhengyi Zhang