Patents by Inventor George M. Whitesides

George M. Whitesides has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20190024644
    Abstract: A soft robot device includes at least a first thermoplastic layer and a second thermoplastic layer, wherein at least one layer is comprised of an extensible thermoplastic material; at least one layer is an inextensible layer; and at least one layer comprises a pneumatic network, wherein the pneumatic network is configured to be in fluidic contact with a pressurizing source, wherein the first and second thermoplastic layers are thermally bonded to each other.
    Type: Application
    Filed: May 29, 2018
    Publication date: January 24, 2019
    Inventors: Jason Ming TING, Alok Suryavamsee TAYI, Bobak MOSADEGH, George M. WHITESIDES
  • Publication number: 20180363683
    Abstract: Systems and methods for providing a soft robot is provided. In one system, a robotic device includes a flexible body having a fluid chamber, where a portion of the flexible body includes an elastically extensible material and a portion of the flexible body is strain limiting relative to the elastically extensible material. The robotic device can further include a pressurizing inlet in fluid communication with the fluid chamber, and a pressurizing device in fluid communication with the pressurizing inlet, the pressurizing device including a reaction chamber configured to accommodate a gas-producing chemical reaction for providing pressurized gas to the pressurizing inlet.
    Type: Application
    Filed: April 13, 2018
    Publication date: December 20, 2018
    Inventors: Robert F. SHEPHERD, Adam STOKES, Stephen A. MORIN, Ludovico CADEMARTIRI, Jacob FREAKE, Rui NUNES, Xin CHEN, George M. WHITESIDES
  • Publication number: 20180326578
    Abstract: Reconfigurable soft robotic actuators with hard components are described. Magnetic attraction is used to couple flexible molded bodies capable of actuation upon pressurization with other flexible molded bodies and/or with hard components (e.g., frames and connectors) to form a seal for fluidic communication and cooperative actuation. Pneumatic de-coupling chambers built into the hard components to de-couple the hard components from the magnetically-coupled soft molded bodies are described. The use of magnetic self-alignment coupling and pneumatic de-coupling allows for the remote assembly and disassembly of complex structures involving hard and soft components. The magnetic coupling allows for rapid, reversible reconfiguration of hybrid soft-hard robots for repair, testing new designs, and carrying out new tasks.
    Type: Application
    Filed: May 8, 2018
    Publication date: November 15, 2018
    Inventors: Sen Wai KWOK, Stephen A. MORIN, Bobak MOSADEGH, Ju-Hee SO, Robert F. SHEPHERD, George M. WHITESIDES
  • Publication number: 20180298925
    Abstract: A soft actuator is described, including: a rotation center having a center of mass; a plurality of bucklable, elastic structural components each comprising a wall defining an axis along its longest dimension, the wall connected to the rotation center in a way that the axis is offset from the center of mass in a predetermined direction; and a plurality of cells each disposed between two adjacent bucklable, elastic structural components and configured for connection with a fluid inflation or deflation source; wherein upon the deflation of the cell, the bucklable, elastic structural components are configured to buckle in the predetermined direction. A soft actuating device including a plurality of the soft actuators and methods of actuation using the soft actuator or soft actuating device disclosed herein are also described.
    Type: Application
    Filed: November 17, 2017
    Publication date: October 18, 2018
    Inventors: Dian YANG, George M. WHITESIDES
  • Publication number: 20180297214
    Abstract: A soft robotic device with a variety of sensors and/or imaging areas is described. The sensor and/or imaging area may be embedded in the soft body or the strain limiting layer of the soft robotic device, attached to the soft body or the strain limiting layer of the soft robotic device, or other-wise linked to the soft body or the strain limiting layer of the soft robotic device.
    Type: Application
    Filed: January 12, 2016
    Publication date: October 18, 2018
    Applicants: President and Fellows of Harvard College, President and Fellows of Harvard College
    Inventors: Joshua Aaron LESSING, George M. WHITESIDES, Yanina SHEVCHENKO, Bobak MOSADEGH, Kevin C. GALLOWAY, Alok Suryavamsee TAYI
  • Patent number: 10082507
    Abstract: An assay method is described, which comprises the steps of immobilizing a binding partner (e.g., an antigen or antibody) for an analyte to be detected (e.g., an antibody or antigen) on a portion of a surface of a microfluidic chamber; passing a fluid sample over the surface and allowing the analyte to bind to the binding partner; allowing a metal colloid, e.g., a gold-conjugated antibody, to associate with the bound analyte; flowing a metal solution, e.g., a silver solution, over the surface such as to form an opaque metallic layer; and detecting the presence of said metallic layer, e.g., by visual inspection or by measuring light transmission through the layer, conductivity or resistance of the layer, or metal concentration in the metal solution after flowing the metal solution over the surface.
    Type: Grant
    Filed: September 30, 2013
    Date of Patent: September 25, 2018
    Assignee: President and Fellows of Harvard College
    Inventors: Samuel K. Sia, Vincent Linder, Babak Parviz, Adam Siegel, George M. Whitesides
  • Patent number: 10048252
    Abstract: A method and apparatus for delivering one or more fluids. Fluids may be delivered from a common vessel to a chemical, biological or biochemical process.
    Type: Grant
    Filed: May 1, 2015
    Date of Patent: August 14, 2018
    Assignee: President and Fellows of Harvard College
    Inventors: Vincent Linder, Samuel K. Sia, George M. Whitesides
  • Publication number: 20180207814
    Abstract: A soft robot is described, including: a flexible and/or stretchable body; a common fluid pressurization unit; and a plurality of fluid chambers each embedded in the flexible and/or stretchable body and capable of fluidic connection with the common fluid pressurization unit through a pressurizing valve; wherein the pressurizing valve is capable of being activated to allow the pressurized fluid to flow from the common fluid pressurization unit into the fluid chamber to result in actuation. Methods of using the soft robot are also described.
    Type: Application
    Filed: July 12, 2016
    Publication date: July 26, 2018
    Inventors: Joshua Aaron LESSING, George M. WHITESIDES
  • Patent number: 10006444
    Abstract: A soft robot device includes at least a first thermoplastic layer and a second thermoplastic layer, wherein at least one layer is comprised of an extensible thermoplastic material; at least one layer is an inextensible layer; and at least one layer comprises a pneumatic network, wherein the pneumatic network is configured to be in fluidic contact with a pressurizing source, wherein the first and second thermoplastic layers are thermally bonded to each other.
    Type: Grant
    Filed: April 13, 2015
    Date of Patent: June 26, 2018
    Assignee: President and Fellows of Harvard College
    Inventors: Jason Ming Ting, Alok Suryavamsee Tayi, Bobak Mosadegh, George M. Whitesides
  • Patent number: 9993921
    Abstract: A soft robot having an integrated electrical component includes an expandable or collapsible body, the body comprising an inlet that is configured to communicate with a fluid source and a flexible strain limited layer secured to a portion of the expandable or collapsible body, wherein the strain limited layer includes at least one electrical component.
    Type: Grant
    Filed: August 21, 2015
    Date of Patent: June 12, 2018
    Assignee: President and Fellows of Harvard College
    Inventors: Joshua Aaron Lessing, Ramses V. Martinez, Alok Suryavamsee Tayi, Jason Ming Ting, George M. Whitesides
  • Patent number: 9992867
    Abstract: A cellulosic substrate-based device is described, including a cellulosic substrate comprising a functionalized surface covalently functionalized by a chemical moiety in an amount sufficient to provide an omniphobic or hydrophobic surface; and a material printed on the functionalized surface, wherein the printed material has a line edge roughness of less than about 15 ?m and/or a line lateral resolution of less than about 50 ?m.
    Type: Grant
    Filed: April 13, 2015
    Date of Patent: June 5, 2018
    Assignee: President and Fellows of Harvard College
    Inventors: Joshua Aaron Lessing, Ana C. Glavan, S. Brett Walker, Christoph Matthias Keplinger, George M. Whitesides
  • Patent number: 9981377
    Abstract: Systems and methods for providing flexible robotic actuators are disclosed. Some embodiments of the disclosed subject matter include a soft robot capable of providing a radial deflection motions; a soft tentacle actuator capable of providing a variety of motions and providing transportation means for various types of materials; and a hybrid robotic system that retains desirable characteristics of both soft robots and hard robots. Some embodiments of the disclosed subject matter also include methods for operating the disclosed robotic systems.
    Type: Grant
    Filed: September 8, 2014
    Date of Patent: May 29, 2018
    Assignee: President and Fellows of Harvard College
    Inventors: Stephen A. Morin, Robert F. Shepherd, Adam Stokes, Filip Ilievski, Ramses V. Martinez, Jamie L. Branch, Carina R. Fish, Lihua Jin, Rui M. D. Nunes, Zhigang Suo, George M. Whitesides
  • Patent number: 9962832
    Abstract: Reconfigurable soft robotic actuators with hard components are described. Magnetic attraction is used to couple flexible molded bodies capable of actuation upon pressurization with other flexible molded bodies and/or with hard components (e.g., frames and connectors) to form a seal for fluidic communication and cooperative actuation. Pneumatic de-coupling chambers built into the hard components to de-couple the hard components from the magnetically-coupled soft molded bodies are described. The use of magnetic self-alignment coupling and pneumatic de-coupling allows for the remote assembly and disassembly of complex structures involving hard and soft components. The magnetic coupling allows for rapid, reversible reconfiguration of hybrid soft-hard robots for repair, testing new designs, and carrying out new tasks.
    Type: Grant
    Filed: March 4, 2014
    Date of Patent: May 8, 2018
    Assignee: President and Fellows of Harvard College
    Inventors: Sen Wai Kwok, Stephen A. Morin, Bobak Mosadegh, Ju-Hee So, Robert F. Shepherd, George M. Whitesides
  • Patent number: 9945397
    Abstract: Systems and methods for providing a soft robot is provided. In one system, a robotic device includes a flexible body having a fluid chamber, where a portion of the flexible body includes an elastically extensible material and a portion of the flexible body is strain limiting relative to the elastically extensible material. The robotic device can further include a pressurizing inlet in fluid communication with the fluid chamber, and a pressurizing device in fluid communication with the pressurizing inlet, the pressurizing device including a reaction chamber configured to accommodate a gas-producing chemical reaction for providing pressurized gas to the pressurizing inlet.
    Type: Grant
    Filed: April 2, 2014
    Date of Patent: April 17, 2018
    Assignee: President and Fellows of Harvard College
    Inventors: Robert F. Shepherd, Adam Stokes, Stephen A. Morin, Ludovico Cademartiri, Jacob Freake, Rui Nunes, Xin Chen, George M. Whitesides
  • Publication number: 20180080922
    Abstract: The disclosed methods use a multi-phase system to separate samples according to the density of an analyte of interest. The method uses a multi-phase system that comprises two or more phase-separated solutions and a phase component such as a surfactant or polymer. The density of the analyte of interest differs from the densities of the rest of the sample. The density of the analyte of interest is substantially the same as one or more phases. Thus, when the sample is introduced to the multi-phase system, the analyte of interest migrates to the phase having the same density as the analyte of interest, passing through one or more phases sequentially.
    Type: Application
    Filed: November 29, 2017
    Publication date: March 22, 2018
    Inventors: Charles R. MACE, Ashok A. KUMAR, Dyann F. WIRTH, George M. WHITESIDES
  • Publication number: 20180031010
    Abstract: A soft buckling linear actuator is described, including: a plurality of substantially parallel bucklable, elastic structural components each having its longest dimension along a first axis; and a plurality of secondary structural components each disposed between and bridging two adjacent bucklable, elastic structural components; wherein every two adjacent bucklable, elastic structural components and the secondary structural components in-between define a layer comprising a plurality of cells each capable of being connected with a fluid inflation or deflation source; the secondary structural components from two adjacent layers are not aligned along a second axis perpendicular to the first axis; and the secondary structural components are configured not to buckle, the bucklable, elastic structural components are configured to buckle along the second axis to generate a linear force, upon the inflation or deflation of the cells. Methods of actuation using the same are also described.
    Type: Application
    Filed: September 13, 2017
    Publication date: February 1, 2018
    Inventors: Dian YANG, George M. WHITESIDES
  • Publication number: 20180003200
    Abstract: A modular pneumatic robotic actuator, including a first elongated hollow structure and a second elongated hollow structure connected to each other at a moveable joint; an inflatable bladder comprised of an elastomeric material disposed at the said joint and immobilized between the first and second hollow structures, wherein the said inflatable bladder inflates preferentially away from the joint; and a restraining membrane comprised of an elastomeric material disposed over the bladder and connecting the first and second hollow structures, wherein the said restraining membrane is relaxed when the bladder is deflated.
    Type: Application
    Filed: August 1, 2017
    Publication date: January 4, 2018
    Inventors: Yanina SHEVCHENKO, George M. WHITESIDES, Adam STOKES, Gabrielle COMPTON
  • Patent number: 9857353
    Abstract: A kit for separating a sample comprising one or more biological analytes of interest using a multi-phase system comprising: a) two or more phase components selected from the group consisting of a polymer, a surfactant, and combinations thereof; b) optionally a tag molecule capable of binding the one or more biological analytes of interest; and c) instructions for: (i) combining the two or more phase-separated solutions with a common solvent to create a multi-phase system; (ii) optionally, combining the biological analyte of interest and tag molecule, and (iii) separating the biological analyte of interest from the sample.
    Type: Grant
    Filed: August 25, 2015
    Date of Patent: January 2, 2018
    Assignee: President and Fellows of Harvard College
    Inventors: Charles R. Mace, Ashok A. Kumar, Dyann F. Wirth, George M. Whitesides
  • Patent number: 9850922
    Abstract: A soft actuator is described, including: a rotation center having a center of mass; a plurality of bucklable, elastic structural components each comprising a wall defining an axis along its longest dimension, the wall connected to the rotation center in a way that the axis is offset from the center of mass in a predetermined direction; and a plurality of cells each disposed between two adjacent bucklable, elastic structural components and configured for connection with a fluid inflation or deflation source; wherein upon the deflation of the cell, the bucklable, elastic structural components are configured to buckle in the predetermined direction. A soft actuating device including a plurality of the soft actuators and methods of actuation using the soft actuator or soft actuating device disclosed herein are also described.
    Type: Grant
    Filed: April 13, 2015
    Date of Patent: December 26, 2017
    Assignee: President and Fellows of Harvard College
    Inventors: Dian Yang, George M. Whitesides
  • Publication number: 20170356899
    Abstract: A method of and system for detecting a gas or vapor includes providing a sensor comprising an electrode pair in electrical contact with a layer of porous material, the porous material layer having water adsorbed on its surface; contacting the sensor with a gas or vapor sample to be analysed; applying a voltage across the electrode pair of the sensor; and measuring a response, the response correlating to the presence of a target gas or vapor.
    Type: Application
    Filed: October 22, 2015
    Publication date: December 14, 2017
    Inventors: Firat GÜDER, Bobak MOSADEGH, Alar AINLA, George M. WHITESIDES