Abstract: A method of aging of alcohol following bottling of the alcohol. The method comprising the steps of fermenting a mash and then distilling the mash to form a concentrated alcohol and temporarily storing the concentrated alcohol within a wooden container to barrel age the concentrated alcohol. During the bottling process, either before the alcohol is added to the individual bottling container or once the alcohol is added individual bottling container, at least one of wood chips, wood shavings and/or wood pieces are added to the interior cavity of the individual bottling container so that the alcohol, once bottled within the individual bottling container, can intimately mix and engage with the wood chips, wood shavings and/or wood pieces and continue the barrel aging process following bottling of the alcohol up until the point in time at which the alcohol is consumed.

Abstract: The invention relates to the field of drug delivery, in particular, to compounds and methods for the chemical modification of a proteinaceous channel to be used in pharmaceutical delivery vehicles for controlled and/or localized release of therapeutic molecules (e.g., small molecules, peptides, proteins or other macromolecules). Provided are pH- and/or light-responsive compounds capable of controlling the channel activity of a mechanosensitive channel, such as the MscL channel protein of E. coli, or a functional equivalent thereof, and use of these compounds to convert a mechanosensitive channel protein into a pH- and/or light-responsive channel. Also provided are drug delivery vehicles comprising a pH- and/or light-responsive channel protein.

Abstract: The present invention relates to a method for producing particles of a compound of interest. In a method according to the invention a solution is provided of the compound of interest in a solvent. This solution is thickened or gelled and particles are formed. The invention further relates to a particle that is obtainable by the invention.

Abstract: The invention is directed to delivery vehicles for delivering a substance of interest to a predetermined site. The delivery vehicle includes a substance and means for inducing availability of at least one compartment of the delivery vehicle toward the exterior, thus, allowing access of the substance to the exterior of the delivery vehicle at the predetermined site. The invention is further directed to uses of the delivery vehicle and methods for preparing the delivery vehicle.

Abstract: There is disclosed an orthopedic cervical pillow which is intended to be used to support the neck and head of a person. The pillow is generally rectangular and is made of an upper casing and a lower casing each being sewn together along their edges to constitute the outer cover of the pillow. The pillow is filled with fibre. In addition, it includes two or more elongated pieces of woven material which are disposed lengthwise and upstanding relative to the pillow. Each of these pieces are sewn along their upper and lower edges by continuous lateral stitching respectively to the upper and lower casings. The pieces of woven material are distributed inside the pillow to constitute one central, one wider and one narrower lateral tubular shaped compartments which extend lengthwise inside the pillow. The narrower lateral compartment is wider than the central compartment.

Abstract: A multimodal cycle for a grinding machine is modified as the function of the grinding force and the mode of operation. The grinding force is monitored by measuring the electrical load value upon the grinding wheel motor during operating conditions and biasing this value by a stored value representative of the nongrinding idle load. The idle load bias is updated with each grinding cycle and the grinding force signal is used to control a variety of machine operations. If the grinding force signal exceeds a predetermined threshold during an early portion of the grinding cycle, the wheelhead advancement is terminated; while the same situation in a later portion of the cycle permits continued wheelhead advancement but at a reduced rate. The grinding force signal is also used to count parts and detect part absence. It is further used to regulate rough and finished spark-outs as well as a peak load limit for the grinding cycle.

Abstract: An apparatus is provided for moving a machine element along a straight line path in a plane defined by two orthogonal axes of motion. A switching device is provided for producing an input signal representing the slope of the straight line path which is defined by the tangent of the angle formed between the path and a first axis of motion. In accordance with mechanisms known in the prior art, first output pulses are generated for moving the machine element along the first axis of motion at an arbitrary velocity. The invention provides a counter circuit having a modulus as a function of the component of slope along the first axis of motion. Further in response to the input signal and each of the first output pulses, the counter circuit increments a number of times represented by the component of slope along the second axis of motion.

Abstract: A machine tool having an electrical means for producing a non-cylindrical surface of revolution.