Patents by Inventor George Steven Morris

George Steven Morris has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Modulators of the SRC-kinase activity for preventing or treating metastatic cancer
    Patent number: 10400008
    Abstract: The invention provides a molecule that modulates an activity of a Src family kinase for use in preventing or treating a metastatic cancer a subject. Preferably, the molecule comprises or consists of the structure: Bj-[(Pro)n-Xr-His-Pro-His-Ala-Arg-Ile-Lys]m-Rp, or Bj-[lys-ile-arg-ala-his-pro-his-xr-(pro)n]m-Rp, or a derivative or fragment thereof, wherein B is a first chemical moiety, j is 0 or 1, n is an integer from 1-10, X is any amino acid, r is an integer from 0 to 2, m is an integer from 1 to 3, R is a second chemical moiety, p is 0 or 1, and [lys-ile-arg-ala-his-pro-his-xr-(pro)n] is the retro-inverso peptide of [(Pro)n-Xr-His-Pro-His-Ala-Arg-Ile-Lys].
    Type: Grant
    Filed: April 30, 2014
    Date of Patent: September 3, 2019
    Assignee: Cancer Research Technology Limited
    Inventors: Satu Vainikka, George Steven Morris, Samuel Ogunsalu, Gabriella Castoria, Antimo Migliaccio, Ferdinando Auricchio
  • Medical Use
    Publication number: 20180273585
    Abstract: The invention provides a molecule that inhibits or prevents an interaction between a Src family kinase and an androgen or estradiol receptor, for use in preventing or treating a non-cancerous condition in which an activity of AR and/or ER is a contributory factor in a subject, or for use in preventing or treating a cancerous condition in which an activity of AR and/or ER is a contributory factor in a subject who wishes to preserve fertility, or for use in preventing or treating a gynaecological condition in which an activity of AR and/or ER is a contributory factor in a subject.
    Type: Application
    Filed: March 19, 2018
    Publication date: September 27, 2018
    Inventors: Mark Eccleston, Satu Vainikka, George Steven Morris
  • Method of treating endometriosis
    Patent number: 10023612
    Abstract: The invention provides a molecule that inhibits or prevents an interaction between a Src family kinase and an androgen or estradiol receptor, for use in preventing or treating a non-cancerous condition in which an activity of AR and/or ER is a contributory factor in a subject, or for use in preventing or treating a cancerous condition in which an activity of AR and/or ER is a contributory factor in a subject who wishes to preserve fertility, or for use in preventing or treating a gynecological condition in which an activity of AR and/or ER is a contributory factor in a subject.
    Type: Grant
    Filed: November 1, 2012
    Date of Patent: July 17, 2018
    Assignee: VALIRX PLC
    Inventors: Mark Eccleston, Satu Vainikka, George Steven Morris
  • MODULATORS OF THE SRC-KINASE ACTIVITY FOR PREVENTING OR TREATING METASTATIC CANCER
    Publication number: 20160068568
    Abstract: The invention provides a molecule that modulates an activity of a Src family kinase for use in preventing or treating a metastatic cancer a subject. Preferably, the molecule comprises or consists of the structure: Bj-[(Pro)n-Xr-His-Pro-His-Ala-Arg-Ile-Lys]m-Rp, or Bj-[lys-ile-arg-ala-his-pro-his-xr-(pro)n]m-Rp, or a derivative or fragment thereof, wherein B is a first chemical moiety, j is 0 or 1, n is an integer from 1-10, X is any amino acid, r is an integer from 0 to 2, m is an integer from 1 to 3, R is a second chemical moiety, p is 0 or 1, and [lys-ile-arg-ala-his-pro-his-xr-(pro)n] is the retro-inverso peptide of [(Pro)n-Xr-His-Pro-His-Ala-Arg-Ile-Lys].
    Type: Application
    Filed: April 30, 2014
    Publication date: March 10, 2016
    Inventors: Satu Vainikka, George Steven Morris, Samuel Ogunsalu, Gabriella Castoria, Antimo Migliaccio, Fernando Auricchio
  • Medical Use
    Publication number: 20140322306
    Abstract: The invention provides a molecule that inhibits or prevents an interaction between a Src family kinase and an androgen or estradiol receptor, for use in preventing or treating a non-cancerous condition in which an activity of AR and/or ER is a contributory factor in a subject, or for use in preventing or treating a cancerous condition in which an activity of AR and/or ER is a contributory factor in a subject who wishes to preserve fertility, or for use in preventing or treating a gynaecological condition in which an activity of AR and/or ER is a contributory factor in a subject.
    Type: Application
    Filed: November 1, 2012
    Publication date: October 30, 2014
    Inventors: Mark Eccleston, Satu Vainikka, George Steven Morris