Patents by Inventor George Zima

George Zima has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20070254859
    Abstract: At least one compound chosen from compounds of Formula I: a pharmaceutically acceptable salt or ester thereof, a solvate thereof, a chelate thereof, a non-covalent complex thereof, a prodrug thereof, and mixtures of any of the foregoing, wherein: n is a number from 1 to 900, wherein the individual units may be the same or different; W is chosen from alkyl, substituted alkyl, cycloalkyl, substituted cycloalkyl, aryl, substituted aryl, aralkyl and substituted aralkyl; each of R2, R3, R4 and R5 is independently chosen from —H, alkyl, substituted alkyl, cycloalkyl, substituted cycloalkyl, aryl, substituted aryl, aralkyl and substituted aralkyl; Z? is chosen from —O—, —N—, —NO—, —NR4—, —S—, —SO— and —SO2—, wherein R4 is defined as above; each of X, X?, Y and Z is independently chosen from —CR4R5—, —NH—, —NR4—, —NO—, —O—, —NOR4—, —S—, —SO—, —SO2—, wherein R4 and R5 are defined as above; R1 is chosen from a tocopherol, a steroid and a flavonoid; and R6 is chosen from any R1, alkyl, substituted alkyl, cycloalkyl
    Type: Application
    Filed: March 30, 2007
    Publication date: November 1, 2007
    Inventors: Michael Wempe, Kevin Edgar, John Hyatt, George Zima
  • Publication number: 20070104850
    Abstract: The present invention provides a process for producing a solid sucrose acetate isobutyrate (SAIB) formulation, by combining sucrose acetate isobutyrate in an amount from about 1 weight percent to about 80 weight percent based on the total weight percent of the total solid formulation; and a solid substrate that is soluble in water or oil, wherein the substrate is present in an amount from about 99 weight percent to about 30 weight percent based on the weight of the formulation, wherein the formulation produced is pourable in less than about 20 seconds according to ASTM method D1895-96. The solid SAIB formulation is useful in beverage applications.
    Type: Application
    Filed: December 20, 2006
    Publication date: May 10, 2007
    Inventors: Phillip Cook, George Zima, Danessa Sexton
  • Publication number: 20060165769
    Abstract: Compounds and compositions are disclosed for increasing the bioavailability of lipophilic drugs, and more specifically, to solubilizing lipophilic drugs using bioenhancers that cause no efflux inhibition or a desired degree of efflux inhibition. Methods of making and using such compositions are also disclosed.
    Type: Application
    Filed: September 29, 2005
    Publication date: July 27, 2006
    Inventors: John Hyatt, George Zima, Kevin Edgar, Lisa Navarro, Claus-Michael Lehr, Eva-Maria Collnot, Andy Singleton, Christiane Baldes, Ulrich Schafer, Michael Wempe
  • Publication number: 20050171052
    Abstract: The present invention provides a solid sucrose acetate isobutyrate formulation having improved handling characteristics.
    Type: Application
    Filed: November 15, 2004
    Publication date: August 4, 2005
    Inventors: Phillip Cook, George Zima, Danessa Sexton
  • Publication number: 20050106304
    Abstract: The present invention provides a solid sucrose acetate isobutyrate (SAIB) formulation, comprising sucrose acetate isobutyrate in an amount from about 1 weight percent to about 80 weight percent based on the total weight percent of the total solid formulation; and a solid substrate that is soluble in water or oil, wherein the substrate is present in an amount from about 99 weight percent to about 30 weight percent based on the weight of the formulation, wherein the formulation is pourable in less than about 20 seconds according to ASTM method D1895-96. The SAIB formulation is useful in beverage applications.
    Type: Application
    Filed: November 14, 2003
    Publication date: May 19, 2005
    Inventors: Phillip Cook, George Zima, Danessa Sexton
  • Publication number: 20050053712
    Abstract: Disclosed is a process for the recovery of a phytolipid composition from a vegetable oil by-product. The phytolipid composition produced comprises squalene, phytosterols, mixed tocopherols and tocotrieneols, and vegetable wax and is useful as an emollient. The phytochemical composition may be applied directly to the skin to provide emolliency. Alternatively, the phytolipid composition may be formulated in various aqueous or anhydrous cosmetic compositions such as creams, lotions, gels, ointments, lip balms, sticks, or pencils for treatment of the skin and lips. The phytolipid composition also may be incorporated into foods, beverages, and nutraceuticals to provide health benefits.
    Type: Application
    Filed: May 12, 2004
    Publication date: March 10, 2005
    Inventors: George Zima, Terry Oldfield, Suzanne Dobbs, Phillip Cook, Charles Kelly, Mary Crow, Craig Hoyme
  • Publication number: 20050051419
    Abstract: Disclosed is a process for the recovery of a phytolipid composition from a vegetable oil by-product. The phytolipid composition produced comprises squalene, phytosterols, mixed tocopherols and tocotrieneols, and vegetable wax and is useful as an emollient. The phytochemical composition may be applied directly to the skin to provide emolliency. Alternatively, the phytolipid composition may be formulated in various aqueous or anhydrous cosmetic compositions such as creams, lotions, gels, ointments, lip balms, sticks, or pencils for treatment of the skin and lips. The phytolipid composition also may be incorporated into foods, beverages, and nutraceuticals to provide health benefits.
    Type: Application
    Filed: September 10, 2003
    Publication date: March 10, 2005
    Inventors: George Zima, Terry Oldfield, Suzanne Dobbs, Phillip Cook, Charles Kelly, Mary Crow, Craig Hoyme