Patents by Inventor George Zonios

George Zonios has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Method for measuring tissue morphology
    Patent number: 6922583
    Abstract: The present invention relates to systems and methods for measuring one or more physical characteristics of material such as tissue using optical radiation. The system can use light that is scattered by a tissue layer to determine, for example, the size of nuclei in the tissue layer to aid in the characterization of the tissue. These methods can include the use of fiber optic devices to deliver and collect light from a tissue region of interest to diagnose, for example, whether the tissue is normal or precancerous.
    Type: Grant
    Filed: April 10, 2000
    Date of Patent: July 26, 2005
    Assignee: Massachusetts Institute of Technology
    Inventors: Lev T. Perelman, Vadim Backman, Michael S. Feld, George Zonios, Irving Itzkan, Ramasamy Manoharan
  • Adaptive calibration for pulse oximetry
    Patent number: 6839580
    Abstract: A method for calibrating a pulse oximeter device and an apparatus incorporating the method and a system for utilizing the method. The method is based on modeling light propagation in tissue at two wavelengths, typically, one in the red and one in the infrared range of the spectrum. A formula is derived relating the arterial oxygen saturation to a ratio R commonly measured by standard pulse oximeters. A specific parameter is identified and utilized in the calibration of the oximeter. This parameter is formulated in terms of the DC signals measured by the pulse oximeter at the two wavelengths. An empirical method for estimating this parameter based on experimental data is also described.
    Type: Grant
    Filed: December 4, 2002
    Date of Patent: January 4, 2005
    Assignee: RIC Investments, Inc.
    Inventors: George Zonios, Vijay K. Iyer, Uday S. Shankar
  • Adaptive calibration for pulse oximetry
    Publication number: 20030114738
    Abstract: A method for calibrating a pulse oximeter device and an apparatus incorporating the method and a system for utilizing the method. The method is based on modeling light propagation in tissue at two wavelengths, typically, one in the red and one in the infrared range of the spectrum. A formula is derived relating the arterial oxygen saturation to a ratio R commonly measured by standard pulse oximeters. A specific parameter is identified and utilized in the calibration of the oximeter. This parameter is formulated in terms of the DC signals measured by the pulse oximeter at the two wavelengths. An empirical method for estimating this parameter based on experimental data is also described.
    Type: Application
    Filed: December 4, 2002
    Publication date: June 19, 2003
    Inventors: George Zonios, Vijay K. Iyer, Uday S. Shankar
  • Measuring tissue morphology
    Patent number: 6091984
    Abstract: The present invention relates to systems and methods for measuring one or more physical characteristics of material such as tissue using optical radiation. The system can use light that is scattered by a tissue layer to determine, for example, the size of nuclei in the tissue layer to aid in the characterization of the tissue. These methods can include the use of fiber optic devices to deliver and collect light from a tissue region of interest to diagnose, for example, whether the tissue is normal or precancerous.
    Type: Grant
    Filed: October 10, 1997
    Date of Patent: July 18, 2000
    Assignee: Massachusetts Institute of Technology
    Inventors: Lev T. Perelman, Vadim Backman, Michael S. Feld, George Zonios, Irving Itzkan, Ramasamy Manoharan