Patents by Inventor Georges Massiot

Georges Massiot has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 9873715
    Abstract: The present invention relates to a compound of the following formula (I) or to a salt, hydrate, or pharmaceutically acceptable solvate thereof, in which R is a monosaccharide or disaccharide residue. The hydroxyl functions of the monosaccharide or disaccharide residue are, independently, optionally substituted for a (C1-C6) alkyl or —C(O)NH—(C1-C6) alkyl group. The invention also relates to the method for preparing said compound, to a pharmaceutical composition containing same, and to the use thereof as a drug, particularly for cancer treatment.
    Type: Grant
    Filed: January 24, 2014
    Date of Patent: January 23, 2018
    Assignees: PIERRE FABRE MEDICAMENT, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS), INSTITUT DE RECHERCHE POUR LE DEVELOPPEMENT (IRD)
    Inventors: Isabelle Carletti, Georges Massiot
  • Publication number: 20150376222
    Abstract: The present invention relates to a compound of the following formula (I) or to a salt, hydrate, or pharmaceutically acceptable solvate thereof, in which R is a monosaccharide or disaccharide residue. The hydroxyl functions of the monosaccharide or disaccharide residue are, independently, optionally substituted for a (C1-C6) alkyl or —C(O)NH—(C1-C6) alkyl group. The invention also relates to the method for preparing said compound, to a pharmaceutical composition containing same, and to the use thereof as a drug, particularly for cancer treatment.
    Type: Application
    Filed: January 24, 2014
    Publication date: December 31, 2015
    Applicants: PIERRE FABRE MEDICAMENT, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS), INSTITUT DE RECHERCHE POUR LE DEVELOPPEMENT (IRD)
    Inventors: Isabelle CARLETTI, Georges MASSIOT
  • Patent number: 8569362
    Abstract: The present invention relates to a polyketide molecule of the following formula (I): or a pharmaceutically acceptable salt thereof, where R1 is a hydrogen atom or a (C1-C7) alkyl group, as well as the method of preparation and use thereof, in particular as an anticancer agent.
    Type: Grant
    Filed: October 28, 2010
    Date of Patent: October 29, 2013
    Assignees: Pierre Fabre Medicament, Centre National de la Recherche Scientifique (CNRS), Institut de Recherche pour le Development (IRD)
    Inventors: Isabelle Carletti, Georges Massiot, Cécile Debitus
  • Publication number: 20120252889
    Abstract: The present invention relates to a polyketide molecule of the following formula (I): or a pharmaceutically acceptable salt thereof, where R1 is a hydrogen atom or a (C1-C7) alkyl group, as well as the method of preparation and use thereof, in particular as an anticancer agent.
    Type: Application
    Filed: October 28, 2010
    Publication date: October 4, 2012
    Applicants: PIERRE FABRE MEDICAMENT, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS), INSTITUT DE RECHERCHE POUR LE DEVELOPPEMENT (IRD)
    Inventors: Isabelle Carletti, Georges Massiot, Cécile Debitus
  • Patent number: 6004568
    Abstract: The object of the invention is the use of a Bertholletia extract, particularly a Bertholletia excelsa extract, for the preparation of a cosmetic or pharmaceutical composition, particularly a dermatological composition. The Bertholletia extract promotes collagen synthesis or has activity against free radicals, for example to combat the effects of skin ageing, to prevent the formation of wrinkles or reduce their depth, or to promote firmer skin. It also has an activity for promoting the incorporation of vitamin C in the skin cells.
    Type: Grant
    Filed: August 11, 1997
    Date of Patent: December 21, 1999
    Assignee: LVMH Recherche
    Inventors: Frederic Bonte, Marc Dumas, Catherine Lavaud, Georges Massiot
  • Patent number: 5807555
    Abstract: The present invention relates to a method and composition for topically administering a Smelophyllum capense extract as a cosmetic, dermatologic, or pharmaceutical composition to promote collagen synthesis. Administration of the composition results in the firming of the skin, improves healing and is suitable for treating various pathologies accompanied with a deficiency in collagen. The extract can also be added to cell culture medium used in the culture of skin cells, particularly skin fibroblasts. The composition can contain between 0.0001% and 1% by weight of the Smelophyllum capense extract, and the extract can be obtained by extraction with a polar solvent. The composition can contain other ingredients including ascorbic acid, madecassic acid, asiatic acid, madecassoside, asiaticoside, alpha-1-protease inhibitor, collagenase inhibitors, elastase inhibitors, lysine, proline, 2-oxoglutarate and ginsenoside Ro.
    Type: Grant
    Filed: June 18, 1997
    Date of Patent: September 15, 1998
    Assignee: LVMH Recherche
    Inventors: Frederic Bonte, Marc Dumas, Catherine Lavaud, Georges Massiot
  • Patent number: 5770223
    Abstract: The invention relates to the use of Medicago saponins for the preparation of cosmetic or pharmaceutical compositions.The invention provides for the incorporation of 0.01% to 5% by weight of a saponin or a corresponding sapogenin, or a plant extract in which it is present, originating in particular from lucerne leaves or roots.The invention makes it possible to promote renewal of the epidermis, stimulate hair regrowth or delay hair loss, or else to combat the effects of ageing on the state of the skin and scalp, as is evident from the Figure.
    Type: Grant
    Filed: November 13, 1996
    Date of Patent: June 23, 1998
    Assignee: LVMH Recherche
    Inventors: Frederic Bonte, Alain Meybeck, Georges Massiot
  • Patent number: 5723149
    Abstract: The invention relates to the use of Medicago saponins for the preparation of cosmetic or pharmaceutical compositions. The invention provides for the incorporation of 0.01% to 5% by weight of a saponin or a corresponding sapogenin, or a plant extract in which it is present, originating in particular from lucerne leaves or roots. The invention makes it possible to promote renewal of the epidermis, stimulate hair regrowth or delay hair loss, or else to combat the effects of ageing on the state of the skin and scalp, as is evident from the FIGURE.
    Type: Grant
    Filed: February 5, 1996
    Date of Patent: March 3, 1998
    Assignee: LVMH Recherche
    Inventors: Frederic Bonte, Alain Meybeck, Georges Massiot