Patents by Inventor Georgios Skliris

Georgios Skliris has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • METHODS AND COMPOSITIONS FOR IDENTIFICATION, ASSESSMENT AND TREATMENT OF CANCERS ASSOCIATED WITH HEDGEHOG SIGNALING
    Publication number: 20150025012
    Abstract: Provided herein are methods, assays and kits for evaluating a sample, e.g., a sample obtained from a cancer patient, to detect one or more hedgehog biomarkers and/or one or more cilium markers. Thus, the invention can be used, inter alia, as a means to identify patients likely to benefit from administration of one or more hedgehog inhibitors, alone or in combination with therapeutic agents; to predict a time course of disease or a probability of a significant event in the disease of a cancer patient; to stratify patient populations; and/or to more effectively treat or prevent a cancer or a tumor associated with hedgehog signaling.
    Type: Application
    Filed: August 8, 2014
    Publication date: January 22, 2015
    Inventors: John R. MacDougall, Juan Guillermo Paez, Karen J. McGovern, Jeffery L. Kutok, Georgios Skliris, Kerry White, Kerrie L. Faia, Marisa Osswalt Peluso, Veronica Travaglione Campbell
  • METHODS AND COMPOSITIONS FOR IDENTIFICATION, ASSESSMENT AND TREATMENT OF CANCERS ASSOCIATED WITH HEDGEHOG SIGNALING
    Publication number: 20120010230
    Abstract: Provided herein are methods, assays and kits for evaluating a sample, e.g., a sample obtained from a cancer patient, to detect one or more hedgehog biomarkers and/or one or more cilium markers. Thus, the invention can be used, inter alia, as a means to identify patients likely to benefit from administration of one or more hedgehog inhibitors, alone or in combination with therapeutic agents; to predict a time course of disease or a probability of a significant event in the disease of a cancer patient; to stratify patient populations; and/or to more effectively treat or prevent a cancer or a tumor associated with hedgehog signaling.
    Type: Application
    Filed: July 8, 2011
    Publication date: January 12, 2012
    Inventors: John R. MacDougall, Juan Guillermo Paez, Karen J. McGovern, Jeffery L. Kutok, Georgios Skliris, Kerry White, Kerrie L. Faia, Marisa Osswalt Peluso, Veronica Travaglione Campbell