Patents by Inventor Gerald L. Mechanic

Gerald L. Mechanic has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Method for extracting lipids from tissue samples using high osmolality storage medium and product
    Patent number: 6350732
    Abstract: A method extracting lipids from tissue samples, particularly collagenous tissue samples for use in preserving the tissue samples, is disclosed. The product of the method of extracting the lipids is also disclosed. Extraction is accomplished by immersing the tissue sample in a medium which is an aqueous solution of a salt and a sugar that is buffered to maintain pH and which has a high (greater than about 4500 mosm) osmolality.
    Type: Grant
    Filed: November 17, 1997
    Date of Patent: February 26, 2002
    Assignee: Carbomedics, Inc.
    Inventors: Mark A. Moore, David T. Cheung, Gerald L. Mechanic, Brian K. Mcilroy
  • Processs for cross-linking collagenous material
    Patent number: 5854397
    Abstract: The present invention relates to a process for cross-linking a proteinaceous material. The process comprises: i) soaking the material to be cross-linked in an agueous solution of high osmolality; ii) incubating the material in an agueous buffer including an amount of a photooxidative catalyst sufficient to catalyze photooxidation of the material; and iii) irradiating the material and the catalyst of step (i) with light that includes a range of wavelengths selectively absorbed by the catalyst. Irradiation is effected under conditions such that cross-linking of the material occurs. In a further embodiment, the present invention relates to a cross-linked product produced by the above-described method.
    Type: Grant
    Filed: January 10, 1997
    Date of Patent: December 29, 1998
    Assignee: University of North Carolina at Chapel Hill
    Inventor: Gerald L. Mechanic
  • Cross-linking collagenous product
    Patent number: 5332475
    Abstract: The present invention relates to a process for cross-linking a proteinaceous material. The process comprises: i) soaking the material to be cross-linked in an agueous solution of high osmolality; ii) incubating the material in an agueous buffer including an amount of a photooxidative catalyst sufficient to catalyze photooxidation of the material; and iii) irradiating the material and the catalyst of step (i) with light that includes a range of wavelengths selectively absorbed by the catalyst. Irradiation is effected under conditions such that cross-linking of the material occurs. In a further embodiment, the present invention relates to a cross-linked product produced by the above-described method.
    Type: Grant
    Filed: March 12, 1992
    Date of Patent: July 26, 1994
    Assignee: University of North Carolina at Chapel Hill
    Inventor: Gerald L. Mechanic
  • Process for cross-linking collagenous material and resulting product
    Patent number: 5147514
    Abstract: The present invention relates to a process for cross-linking a proteinaceous material. The process comprises: i) soaking the material to be cross-linked in an aqueous solution of high osmolality; ii) incubating the material in an aqueous buffer including an amount of a photooxidative catalyst sufficient to catalyze photooxidation of the material; and iii) irradiating the material and the catalyst of step (i) with light that includes a range of wavelengths selectively absorbed by the catalyst. Irradiation is effected under conditions such that cross-linking of the material occurs. In a further embodiment, the present invention relates to a cross-linked product produced by the above-described method.
    Type: Grant
    Filed: July 30, 1990
    Date of Patent: September 15, 1992
    Assignee: University of North Carolina
    Inventor: Gerald L. Mechanic