Patents by Inventor Gerald Loeb
Gerald Loeb has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20240050737Abstract: The present invention provides an advancement in the art of cardiac pacemakers. The invention provides a novel and unobvious pacemaker system that comprises at least one pacemaker and that is, to a large extent, self-controlled, allows for long-term implantation in a patient, and minimizes current inconveniences and problems associated with battery life. The invention further includes a mechanism in which at least two pacemakers are implanted in a patient, and in which the pacemakers communicate with each other at the time of a given pacing or respiratory event, without any required external input, and adjust pacing parameters to respond to the patient's need for blood flow. The invention further provides a novel design for a pacemaker in which the pacemaker electrode is connected to the pacemaker body by a lead that is configured to allow the pacemaker to lie parallel to the epicardial surface and to reduce stress on the pacemaker and heart tissue.Type: ApplicationFiled: August 15, 2023Publication date: February 15, 2024Inventors: Yaniv Bar-Cohen, Gerald Loeb, Li Zhou, Raymond Peck, Steven Nutt
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Patent number: 11724104Abstract: The present invention provides an advancement in the art of cardiac pacemakers. The invention provides a novel and unobvious pacemaker system that comprises at least one pacemaker and that is, to a large extent, self-controlled, allows for long-term implantation in a patient, and minimizes current inconveniences and problems associated with battery life. The invention further includes a mechanism in which at least two pacemakers are implanted in a patient, and in which the pacemakers communicate with each other at the time of a given pacing or respiratory event, without any required external input, and adjust pacing parameters to respond to the patient's need for blood flow. The invention further provides a novel design for a pacemaker in which the pacemaker electrode is connected to the pacemaker body by a lead that is configured to allow the pacemaker to lie parallel to the epicardial surface and to reduce stress on the pacemaker and heart tissue.Type: GrantFiled: June 1, 2021Date of Patent: August 15, 2023Assignees: CHILDREN'S HOSPITAL LOS ANGELES, UNIVERSITY OF SOUTHERN CALIFORNIAInventors: Yaniv Bar-Cohen, Gerald Loeb, Li Zhou, Raymond Peck, Steven Nutt
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Publication number: 20220409865Abstract: The present invention provides a novel design for sheaths intended for medical procedures. The sheath includes structures that anchor the sheath in a cavity or space when deployed but are at the same time retractable such that the sheath can be removed without tearing the tissue defining the space.Type: ApplicationFiled: September 6, 2022Publication date: December 29, 2022Inventors: Yaniv Bar-Cohen, Gerald Loeb
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Patent number: 11433222Abstract: The present invention provides a novel design for sheaths intended for medical procedures. The sheath includes structures that anchor the sheath in a cavity or space when deployed but are at the same time retractable such that the sheath can be removed without tearing the tissue defining the space.Type: GrantFiled: February 22, 2016Date of Patent: September 6, 2022Assignees: CHILDREN'S HOSPITAL LOS ANGELES, UNIVERSITY OF SOUTHERN CALIFORNIAInventors: Yaniv Bar-Cohen, Gerald Loeb
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Patent number: 11376424Abstract: An open coiled pacemaker lead is provided that has improved structural stability and functional life in vivo. The open coiled lead includes an electrically conductive material that is coated or covered by a thin layer of electrically insulative material. The coated coiled lead has adequate spacing between adjacent coils, and has a lumen of sufficient diameter, to allow for infiltration of biological connective tissue onto the surface of the coated coil when maintained in vivo for a sufficient amount of time. Infiltration of the connective tissue essentially uniformly along the entire coiled lead strengthens and lengthens the functional life of the coated coil lead.Type: GrantFiled: March 31, 2016Date of Patent: July 5, 2022Assignees: CHILDREN'S HOSPITAL LOS ANGELES, UNIVERSITY OF SOUTHERN CALIFORNIAInventors: Yaniv Bar-Cohen, Gerald Loeb, Li Zhou, Xiao Yun
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Publication number: 20220054826Abstract: The present invention provides an advancement in the art of cardiac pacemakers. The invention provides a novel and unobvious pacemaker system that comprises at least one pacemaker and that is, to a large extent, self-controlled, allows for long-term implantation in a patient, and minimizes current inconveniences and problems associated with battery life. The invention further includes a mechanism in which at least two pacemakers are implanted in a patient, and in which the pacemakers communicate with each other at the time of a given pacing or respiratory event, without any required external input, and adjust pacing parameters to respond to the patient's need for blood flow. The invention further provides a novel design for a pacemaker in which the pacemaker electrode is connected to the pacemaker body by a lead that is configured to allow the pacemaker to lie parallel to the epicardial surface and to reduce stress on the pacemaker and heart tissue.Type: ApplicationFiled: June 1, 2021Publication date: February 24, 2022Inventors: Yaniv Bar-Cohen, Gerald Loeb, Li Zhou, Raymond Peck, Steven Nutt
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Patent number: 11020588Abstract: The present invention provides advancements in the art of cardiac pacemakers. The invention provides a pacemaker system that comprises at least one pacemaker and that is, to a large extent, self-controlled, allows for long-term implantation in a patient, and minimizes current inconveniences and problems associated with battery life. The invention further includes a mechanism in which at least two pacemakers are implanted in a patient, and in which the pacemakers communicate with each other at the time of a given pacing or respiratory event, without any required external input, and adjust pacing parameters to respond to the patient's need for blood flow. The invention further provides a design for a pacemaker in which the pacemaker electrode is connected to the pacemaker body by a lead that is configured to allow the pacemaker to lie parallel to the epicardial surface and to reduce stress on the pacemaker and heart tissue.Type: GrantFiled: May 8, 2014Date of Patent: June 1, 2021Assignees: CHILDREN'S HOSPITAL LOS ANGELES, UNIVERSITY OF SOUTHERN CALIFORNIAInventors: Yaniv Bar-Cohen, Gerald Loeb, Li Zhou, Raymond Peck, Steven Nutt
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Publication number: 20180085571Abstract: An open coiled pacemaker lead is provided that has improved structural stability and functional life in vivo. The open coiled lead includes an electrically conductive material that is coated or covered by a thin layer of electrically insulative material. The coated coiled lead has adequate spacing between adjacent coils, and has a lumen of sufficient diameter, to allow for infiltration of biological connective tissue onto the surface of the coated coil when maintained in vivo for a sufficient amount of time. Infiltration of the connective tissue essentially uniformly along the entire coiled lead strengthens and lengthens the functional life of the coated coil lead.Type: ApplicationFiled: March 31, 2016Publication date: March 29, 2018Inventors: Yaniv Bar-Cohen, Gerald Loeb, Li Zhou, Xiao Yun
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Publication number: 20180028790Abstract: The present invention provides a novel design for sheaths intended for medical procedures. The sheath includes structures that anchor the sheath in a cavity or space when deployed but are at the same time retractable such that the sheath can be removed without tearing the tissue defining the space.Type: ApplicationFiled: February 22, 2016Publication date: February 1, 2018Inventors: Yaniv Bar-Cohen, Gerald Loeb
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Publication number: 20160228713Abstract: The present invention provides advancements in the art of cardiac pacemakers. The invention provides a pacemaker system that comprises at least one pacemaker and that is, to a large extent, self-controlled, allows for long-term implantation in a patient, and minimizes current inconveniences and problems associated with battery life. The invention further includes a mechanism in which at least two pacemakers are implanted in a patient, and in which the pacemakers communicate with each other at the time of a given pacing or respiratory event, without any required external input, and adjust pacing parameters to respond to the patient's need for blood flow. The invention further provides a design for a pacemaker in which the pacemaker electrode is connected to the pacemaker body by a lead that is configured to allow the pacemaker to lie parallel to the epicardial surface and to reduce stress on the pacemaker and heart tissue.Type: ApplicationFiled: May 8, 2014Publication date: August 11, 2016Applicants: CHILDREN'S HOSPITAL LOS ANGELES, UNIVERSITY OF SOUTHERN CALIFORNIAInventors: Yaniv BAR-COHEN, Gerald LOEB, Li ZHOU, Raymond PECK, Stephen NUTT
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Patent number: 9393407Abstract: A fully implantable cardiac pacemaker system is provided. The pacemaker system includes a pacemaker having an electrode sub-assembly containing an electrode and a base into which the electrode is embedded. It also includes an implantable package that has electronic components for providing electrical pulses to a patient's heart. The pacemaker also has a power supply and a flexible electrically conductive lead that connects the electronic components to the electrode. In addition to the pacemaker, the pacemaker system includes a removable insertion casing that is physically attached to the base portion of the electrode sub-assembly. Upon insertion of the pacemaker into a patient's heart, the pacemaker is detached from the removable insertion casing and deployed fully in the patient's chest. The pacemaker system has particular use in fetal applications.Type: GrantFiled: April 5, 2013Date of Patent: July 19, 2016Assignees: Children's Hospital Los Angeles, University of Southern CaliforniaInventors: Yaniv Bar-Cohen, Gerald Loeb, Michael Silka, Ramen Chmait
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Publication number: 20150088221Abstract: A fully implantable cardiac pacemaker system is provided. The pacemaker system includes a pacemaker having an electrode sub-assembly containing an electrode and a base into which the electrode is embedded. It also includes an implantable package that has electronic components for providing electrical pulses to a patient's heart. The pacemaker also has a power supply and a flexible electrically conductive lead that connects the electronic components to the electrode. In addition to the pacemaker, the pacemaker system includes a removable insertion casing that is physically attached to the base portion of the electrode sub-assembly. Upon insertion of the pacemaker into a patient's heart, the pacemaker is detached from the removable insertion casing and deployed fully in the patient's chest. The pacemaker system has particular use in fetal applications.Type: ApplicationFiled: April 5, 2013Publication date: March 26, 2015Applicants: Univserity of Southern California, Children's Hospital Los AngelesInventors: Yaniv Barr-Cohen, Gerald Loeb, Michael Silka, Ramen Chmait
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Publication number: 20070270722Abstract: A signal transmitting and receiving system to track the position and orientation of limb segments in order to provide feedback information for the control of the limb movement. The user will generally be seated in a wheelchair that provides a structure upon which orthogonal and/or non-orthogonally oriented coils can be mounted and energized selectively so as to create variously oriented magnetic fields. Multiple wireless sensors injected into the limb detect the local field strength and send information telemetrically to a central controller. The controller extracts information about the position and orientation of each limb segment by combining signals from various sensors according to calibration information and optimal filtering methods for extracting information from multiple nonlinear sensors in mechanically constrained systems.Type: ApplicationFiled: February 26, 2007Publication date: November 22, 2007Inventors: Gerald Loeb, Wei Tan
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Publication number: 20070265582Abstract: Devices and methods for positioning an implant at a target location in the body. The methods include testing an implant while within an injection device at a target location to determine whether the implant is functioning effectively. The methods also include testing from or delivery of materials to the target location during implantation, and loading the injection device for use. The device may be configured to permit the longitudinal and/or axial position of the implant to be maintained relative to an injection device during implantation. The device may also be configured to permit testing of the implant. Implants configured for use in the injection devices may also be included.Type: ApplicationFiled: February 28, 2007Publication date: November 15, 2007Inventors: Hilton Kaplan, Gerald Loeb
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Publication number: 20070227267Abstract: Disclosed is a tactile sensory system consisting of set of sensors that work by measuring impedance among plurality of electrodes. The electrodes are deployed on a substantially rigid structure that is protected form the direct contact with external objects by overlying deformable structures. These mechanical structures have similarities to the biological relationships among the distal phalanx, overlying finger pulp and covering skin and nail. Signal information is extracted form these sensors that is related to canonical physical representations used to describe stimuli to be sensed.Type: ApplicationFiled: March 28, 2007Publication date: October 4, 2007Inventors: Gerald Loeb, Roland Johansson
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Publication number: 20070129772Abstract: Systems and methods for fitting cochlear implants. The cochlear implant fitting systems and methods can be used to generate various stimulus patterns for fitting patients with speech processors for cochlear implants. The fitting systems and methods provide means to identify rapidly which of several speech processing strategies could function effectively in cochlear implant patients.Type: ApplicationFiled: August 31, 2006Publication date: June 7, 2007Inventor: Gerald Loeb
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Publication number: 20070118197Abstract: Devices and systems for recording and/or stimulating electrical signals in order to identify a target site within a patient's brain for further electrical stimulation and chemical treatments of the brain. The deep brain stimulation devices and methods include implantable devices having various microelectrode configurations and drug delivery mechanisms. The devices can be used to treat a variety of neurological conditions.Type: ApplicationFiled: July 12, 2006Publication date: May 24, 2007Inventor: Gerald Loeb
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Publication number: 20070048226Abstract: A probe device for detecting chemotherapy effectiveness, and methods of use are disclosed. The device includes a fiber optic probe element that can be injected into a tumor. The probe element is connected to an external controlling/measurement element, which injects a reagent through the probe and into the tumor. The reagent reacts with biological markers indicative of chemotherapy effectiveness.Type: ApplicationFiled: February 8, 2006Publication date: March 1, 2007Inventors: Gerald Loeb, Laura Marcu, Sanmao Kang, Kuo-Chih Liao
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Publication number: 20070016265Abstract: Disclosed are methods and systems for a virtual reality simulation and display of limb movement that facilitate the development and fitting of prosthetic control of a paralyzed or artificial limb. The user generates command signals that are then processed by the control system. The output of the control system drives a physics-based simulation of the limb that simulates the limb to be controlled. The computed movements of the model limb are displayed to the user as a 3D animation from the perspective of the user so as to give the impression that the user is watching the actual movements of his/her own limb. The user learns to adjust his/her command signals to perform tasks successfully with the virtual limb. Alternatively or additionally, the errors produced by the virtual limb and/or the responses of the user during the training process can provide information for adapting the properties of the control system itself.Type: ApplicationFiled: February 9, 2006Publication date: January 18, 2007Inventors: Rahman Davoodi, Gerald Loeb, Junkwan Lee
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Publication number: 20070010726Abstract: A biosensing device for detecting biological analytes, and methods of use and manufacture, are disclosed. The device includes a biosensing element that can remain implanted for extended periods of time. The biosensing element is connected to an optical fiber terminating outside of the body. The optical fiber is also connected to an information analyzer. The information analyzer receives light from the reaction of fluorescent molecules in the biosensing element. The biosensing device can be used to detect and analyze the effectiveness of chemotherapy agents and molecules associated with various diseases.Type: ApplicationFiled: February 8, 2006Publication date: January 11, 2007Inventors: Gerald Loeb, Thomas George, Cesar Blanco, Laura Marcu