Patents by Inventor Gerald M. McGeehan

Gerald M. McGeehan has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Substituted (aryl, heteroaryl, arylmethyl or heteroarylmethyl) hydroxamic acid compounds
    Patent number: 6057369
    Abstract: This invention is directed to compounds of formula I: ##STR1## wherein the variables are as described herein. Compounds within the scope of the present invention possess useful properties, more particularly pharmaceutical properties. They are especially useful for inhibiting the production or physiological effects of TNF in the treatment of a patient suffering from a disease state associated with a physiologically detrimental excess of tumor necrosis factor (TNF). Compounds within the scope of the present invention also inhibit cyclic AMP phosphodiesterase, and are useful in treating a disease state associated with pathological conditions that are modulated by inhibiting cyclic AMP phosphodiesterase, such disease states including inflammatory and autoimmune diseases, in particular type IV cyclic AMP phosphodiesterase.
    Type: Grant
    Filed: September 12, 1997
    Date of Patent: May 2, 2000
    Assignee: Rhone-Poulenc Rorer Pharmaceuticals Inc.
    Inventors: Robert D. Groneberg, Kent W. Neuenschwander, Stevan W. Djuric, Gerald M. McGeehan, Christopher J. Burns, Steven M. Condon, Matthew M. Morrissette, Joseph M. Salvino, Anthony C. Scotese, John W. Ullrich
  • Composition for inhibition of ethylene production in plants
    Patent number: 4851035
    Abstract: An ethylene biosynthesis inhibitor is provided comprising 2-cycloalkyl-1-aminocyclopropanecarboxylic acids or a derivative thereof. By applying the subject compound in an ethylene-production-inhibiting amount, ripening and senescence can be slowed. The compound finds use in conjunction with the inhibition of ripening and improved storage of fruits, vegetables and cut flowers.
    Type: Grant
    Filed: May 1, 1986
    Date of Patent: July 25, 1989
    Assignee: The Board of Trustees of the Leland Stanford Junior University, Stanford University
    Inventors: Michael C. Pirrung, Gerald M. McGeehan