Patents by Inventor Gerald M. Wilson

Gerald M. Wilson has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Compounds that inhibit human DNA ligases and methods of treating cancer
    Patent number: 9757375
    Abstract: Methods for treating cancer using compounds that inhibit human DNA ligases. Methods for using compounds that inhibit human DNA ligases to provide insights into the reaction mechanisms of human DNA ligases, for example to identify the human DNA ligase involved in different DNA repair pathways. Screening methods for compounds that inhibit human DNA ligases.
    Type: Grant
    Filed: June 3, 2015
    Date of Patent: September 12, 2017
    Assignee: University of Maryland, Baltimore
    Inventors: Alan E. Tomkinson, Helen Xi Chen, Barbara Dziegielewska, Alexander D. Mackerell, Shijun Zhong, Gerald M. Wilson
  • COMPOUNDS THAT INHIBIT HUMAN DNA LIGASES AND METHODS OF TREATING CANCER
    Publication number: 20150313898
    Abstract: Methods for treating cancer using compounds that inhibit human DNA ligases. Methods for using compounds that inhibit human DNA ligases to provide insights into the reaction mechanisms of human DNA ligases, for example to identify the human DNA ligase involved in different DNA repair pathways. Screening methods for compounds that inhibit human DNA ligases.
    Type: Application
    Filed: June 3, 2015
    Publication date: November 5, 2015
    Inventors: Alan E. Tomkinson, Helen Xi Chen, Barbara Dziegielewska, Alexander D. Mackerell, Shijun Zhong, Gerald M. Wilson
  • Compounds that inhibit human DNA ligases and methods of treating cancer
    Patent number: 9073896
    Abstract: Methods for treating cancer using compounds that inhibit human DNA ligases. Methods for using compounds that inhibit human DNA ligases to provide insights into the reaction mechanisms of human DNA ligases, for example to identify the human DNA ligase involved in different DNA repair pathways. Screening methods for compounds that inhibit human DNA ligases.
    Type: Grant
    Filed: April 17, 2013
    Date of Patent: July 7, 2015
    Assignee: University of Maryland, Baltimore
    Inventors: Alan E. Tomkinson, Helen Xi Chen, Barbara Dziegielewska, Alexander D. Mackerell, Shijun Zhong, Gerald M. Wilson
  • Compounds that inhibit human DNA ligases and methods of treating cancer
    Publication number: 20140113891
    Abstract: Methods for treating cancer using compounds that inhibit human DNA ligases. Methods for using compounds that inhibit human DNA ligases to provide insights into the reaction mechanisms of human DNA ligases, for example to identify the human DNA ligase involved in different DNA repair pathways. Screening methods for compounds that inhibit human DNA ligases.
    Type: Application
    Filed: April 17, 2013
    Publication date: April 24, 2014
    Inventors: Alan E. Tomkinson, Xi Chen, Barbara Dziegielewska, Alexander D. Mackerell, Shijun Zhong, Gerald M. Wilson
  • Compounds that inhibit human DNA ligases and methods of treating cancer
    Patent number: 8445537
    Abstract: Methods for treating cancer using compounds that inhibit human DNA ligases. Methods for using compounds that inhibit human DNA ligases to provide insights into the reaction mechanisms of human DNA ligases, for example to identify the human DNA ligase involved in different DNA repair pathways. Screening methods for compounds that inhibit human DNA ligases.
    Type: Grant
    Filed: October 9, 2009
    Date of Patent: May 21, 2013
    Assignee: STC.UNM
    Inventors: Alan E. Tomkinson, Xi Chen, Barbara Dziegielewska, Alexander D. Mackerell, Shijun Zhong, Gerald M. Wilson
  • COMPOUNDS THAT INHIBIT HUMAN DNA LIGASES AND METHODS OF TREATING CANCER
    Publication number: 20100099683
    Abstract: Methods for treating cancer using compounds that inhibit human DNA ligases. Methods for using compounds that inhibit human DNA ligases to provide insights into the reaction mechanisms of human DNA ligases, for example to identify the human DNA ligase involved in different DNA repair pathways. Screening methods for compounds that inhibit human DNA ligases.
    Type: Application
    Filed: October 9, 2009
    Publication date: April 22, 2010
    Inventors: Alan E. TOMKINSON, Xi CHEN, Barbara DZIEGIELEWSKA, Alexander D. MACKERELL, Shijun ZHONG, Gerald M. Wilson
  • COMPOSITIONS AND METHODS FOR DIAGNOSING AND TREATING CANCER
    Publication number: 20100055705
    Abstract: The invention is drawn novel methods and compositions for the treatment of cancer, and for the diagnosis and prognosis of cancer in a subject. In particular aspects, the invention relates to the finding that the protein tristetraprolin (TTP) is decreased or repressed in a myriad and diversity of cancers. To this end, TTP represents a viable therapeutic option for the treatment of cancer. Additionally, TTP represents a clinically useful biomarker for the diagnosis and prognosis of cancer.
    Type: Application
    Filed: August 31, 2009
    Publication date: March 4, 2010
    Inventors: Gerald M. Wilson, Sarah Brennan, Nadim Alkharouf, Yuki Kuwano, Perry Blackshear, Myriam Gorospe
  • Cast venting apparatus
    Patent number: 3998220
    Abstract: A surgical cast venting device including an upstanding portion extending through a cast wall and having a bore therein, and a disc-shaped portion disposed in the interior of the cast and in cooperation with the upstanding portion. The disc-shaped portion has a central bore extending through one face thereof, and a plurality of generally radially extending fluid passageways extending from the circumference of the disc-shaped portion to the central bore thereof, and in fluid communication with the central bore and the bore in the upstanding portion. The venting device provides for maximum circulation with a minimum potential for irritation of a patient's skin.
    Type: Grant
    Filed: March 4, 1976
    Date of Patent: December 21, 1976
    Inventors: Clarence W. Cleer, Jr., Gerald M. Wilson