Patents by Inventor Gerald Maxwell Cherf

Gerald Maxwell Cherf has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • PROGRANULIN VARIANTS
    Publication number: 20230265137
    Abstract: Provided herein are progranulin variants and fusion proteins that comprise a progranulin variant and an Fc polypeptide. Methods of using such proteins to treat progranulin-associated disorders (e.g., a neurodegenerative disease, such as frontotemporal dementia (FTD)) are also provided herein.
    Type: Application
    Filed: March 24, 2023
    Publication date: August 24, 2023
    Applicant: Denali Therapeutics Inc.
    Inventors: Gerald Maxwell Cherf, Gunasekaran Kannan, Katrina W. Lexa, Ray L. Y. Low, Rachel Prorok, Ankita Srivastava
  • Progranulin variants
    Patent number: 11643446
    Abstract: Provided herein are progranulin variants and fusion proteins that comprise a progranulin variant and an Fc polypeptide. Methods of using such proteins to treat progranulin-associated disorders (e.g., a neurodegenerative disease, such as frontotemporal dementia (FTD)) are also provided herein.
    Type: Grant
    Filed: March 17, 2022
    Date of Patent: May 9, 2023
    Assignee: Denali Therapeutics Inc.
    Inventors: Gerald Maxwell Cherf, Gunasekaran Kannan, Katrina W. Lexa, Ray L. Y. Low, Rachel Prorok, Ankita Srivastava
  • PROGRANULIN VARIANTS
    Publication number: 20220220172
    Abstract: Provided herein are progranulin variants and fusion proteins that comprise a progranulin variant and an Fc polypeptide. Methods of using such proteins to treat progranulin-associated disorders (e.g., a neurodegenerative disease, such as frontotemporal dementia (FTD)) are also provided herein.
    Type: Application
    Filed: March 18, 2022
    Publication date: July 14, 2022
    Applicant: Denali Therapeutics Inc.
    Inventors: Gerald Maxwell Cherf, Gunasekaran Kannan, Katrina W. Lexa, Ray L.Y. Low, Rachel Prorok, Ankita Srivastava
  • PROGRANULIN VARIANTS
    Publication number: 20220213155
    Abstract: Provided herein are progranulin variants and fusion proteins that comprise a progranulin variant and an Fc polypeptide. Methods of using such proteins to treat progranulin-associated disorders (e.g., a neurodegenerative disease, such as frontotemporal dementia (FTD)) are also provided herein.
    Type: Application
    Filed: March 17, 2022
    Publication date: July 7, 2022
    Applicant: Denali Therapeutics Inc.
    Inventors: Gerald Maxwell Cherf, Gunasekaran Kannan, Katrina W. Lexa, Ray L.Y. Low, Rachel Prorok, Ankita Srivastava
  • PROGRANULIN VARIANTS
    Publication number: 20210188925
    Abstract: Provided herein are progranulin variants and fusion proteins that comprise a progranulin variant and an Fc polypeptide. Methods of using such proteins to treat progranulin-associated disorders (e.g., a neurodegenerative disease, such as frontotemporal dementia (FTD)) are also provided herein.
    Type: Application
    Filed: January 26, 2021
    Publication date: June 24, 2021
    Applicant: Denali Therapeutics Inc.
    Inventors: Gerald Maxwell Cherf, Gunasekaran Kannan, Katrina W. Lexa, Ray L.Y. Low, Rachel Prorok, Ankita Srivastava
  • CONTROL OF DNA MOVEMENT IN A NANOPORE AT ONE NUCLEOTIDE PRECISION BY A PROCESSIVE ENZYME
    Publication number: 20140051068
    Abstract: The invention herein disclosed provides for devices and methods that can detect and control an individual polymer in a mixture is acted upon by another compound, for example, an enzyme, in a nanopore. Of particular note is the stability of the system in a saline medium and to detect individual nucleotide bases in a polynucleotide in real time and which may be used to sequence DNA for many hours without change of reagents. The invention is of particular use in the fields of forensic biology, molecular biology, structural biology, cell biology, molecular switches, molecular circuits, and molecular computational devices, and the manufacture thereof.
    Type: Application
    Filed: September 7, 2011
    Publication date: February 20, 2014
    Applicant: The Regents of the University of California
    Inventors: Gerald Maxwell Cherf, Kathy R. Lieberman, Christopher Evan Lam, Michael Doody, Mark A. Akeson