Patents by Inventor Gerald R. Magneson

Gerald R. Magneson has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • COMPOSITIONS FOR RADIOLABELING DIETHYLENETRIAMINEPENTAACETIC ACID (DTPA)-DEXTRAN
    Publication number: 20160347679
    Abstract: The subject invention relates to the compositions for radiolabeling Diethylenetriaminepentaacetic Acid (DTPA)-dextran with Technetium-99m and for stabilizing the DTPA-dextran Cold Kit. The composition contains Stannous Chloride ions to reduce 99mTc-pertechnetate, Ascorbic Acid to reduce stannic ions to stannous ions to maintain a reducing environment, ?,?-Trehalose to add bulk and to stabilize the lyophilized composition without interfering with the radiochemical yield, and Glycine to transchelate Technetium-99m under highly acidic conditions to facilitate radiolabeling DTPA-dextran with high radiochemical purity. In addition, the invention pertains to methods for making and using the compositions. The reconstitution of the lyophilized composition by 99mTc-pertechnetate, resulting in radiolabeled 99mTc-DTPA-dextran in a composition between pH 3 to 4.
    Type: Application
    Filed: August 10, 2016
    Publication date: December 1, 2016
    Inventors: Gerald R. Magneson, Richard Cushman Orahood
  • FORMULATIONS OF LIQUID STABLE ANTITHROMBIN
    Publication number: 20160129115
    Abstract: In one aspect, the invention provides liquid stable formulations of antithrombin.
    Type: Application
    Filed: June 19, 2015
    Publication date: May 12, 2016
    Applicant: LFB USA, Inc.
    Inventors: Gerald R. Magneson, Greg J. Allard, Nicholas C. Masiello, Usha S. Patel, Lauren K. Fontana, Joseph L. Pearce, Jerry A. Grandoni
  • FORMULATIONS OF LIQUID STABLE ANTITHROMBIN
    Publication number: 20110082083
    Abstract: In one aspect, the invention provides liquid stable formulations of antithrombin.
    Type: Application
    Filed: May 3, 2010
    Publication date: April 7, 2011
    Applicant: GTC Biotherapeutics, Inc.
    Inventors: Gerald R. Magneson, Greg J. Allard, Nicholas C. Masiello, Usha S. Patel, Lauren K. Fontana, Joseph L. Pearce, Jerry A. Grandoni
  • Compositions for stabilizing proteins for long term dry storage and methods of making and using the compositions
    Patent number: 5547873
    Abstract: The invention relates to a composition for stabilizing proteins for long term dry storage and superior recovery of their native protein structure for extended reconstituted stability at 2.degree.-8.degree. C. The composition comprises: 1) a defibrinated sodium-free blood plasma, 2) a glass-forming sugar, 3) a serum albumin and/or a gelatin, and 4) a potassium salt. In another aspect, the present invention relates to a method for stabilizing a protein for long term dry storage using the above mentioned composition.
    Type: Grant
    Filed: February 22, 1994
    Date of Patent: August 20, 1996
    Assignee: Genzyme Corporation
    Inventors: Gerald R. Magneson, David L. Reichenbach