Patents by Inventor Gerald Siefring, Jr.

Gerald Siefring, Jr. has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • METHODS FOR DETECTION OF IMMUNOSUPPRESSANT DRUGS
    Publication number: 20100297670
    Abstract: Methods and reagents are disclosed for enhancing the bioavailability of a hydrophobic drug, and in some embodiments for determining a hydrophobic drug, in a sample suspected of containing a hydrophobic drug. A combination is formed in a medium where the combination comprises the sample, a hemolytic agent where a determination of the hydrophobic drug is conducted, and a bioavailability agent for the hydrophobic drug. The bioavailability agent comprises an ionic detergent comprising a chain of at least 10 carbon atoms or a non-ionic detergent comprising a chain of at least 15 repeating ethylene oxide units or propylene oxide units or a combination of ethylene oxide units and propylene oxide units. The concentration of the bioavailability agent in the medium is sufficient to enhance the bioavailability of the hydrophobic drug.
    Type: Application
    Filed: July 28, 2010
    Publication date: November 25, 2010
    Applicant: SIEMENS HEALTHCARE DIAGNOSTICS INC.
    Inventors: Tie Q. Wei, Gerald Siefring, JR., Christy Schaible, Amy Posey
  • Methods for detection of immunosuppressant drugs
    Patent number: 7790401
    Abstract: Methods and reagents are disclosed for enhancing the bioavailability of a hydrophobic drug, and in some embodiments for determining a hydrophobic drug, in a sample suspected of containing a hydrophobic drug. A combination is formed in a medium where the combination comprises the sample, a hemolytic agent where a determination of the hydrophobic drug is conducted, and a bioavailability agent for the hydrophobic drug. The bioavailability agent comprises an ionic detergent comprising a chain of at least 10 carbon atoms or a non-ionic detergent comprising a chain of at least 15 repeating ethylene oxide units or propylene oxide units or a combination of ethylene oxide units and propylene oxide units. The concentration of the bioavailability agent in the medium is sufficient to enhance the bioavailability of the hydrophobic drug.
    Type: Grant
    Filed: August 6, 2007
    Date of Patent: September 7, 2010
    Assignee: Siemens Healthcare Diagnostics
    Inventors: Tie Q. Wei, Gerald Siefring, Jr., Christy Schaible, Amy Posey
  • METHODS FOR DETECTION OF IMMUNOSUPPRESSANT DRUGS
    Publication number: 20090042223
    Abstract: Methods and reagents are disclosed for enhancing the bioavailability of a hydrophobic drug, and in some embodiments for determining a hydrophobic drug, in a sample suspected of containing a hydrophobic drug. A combination is formed in a medium where the combination comprises the sample, a hemolytic agent where a determination of the hydrophobic drug is conducted, and a bioavailability agent for the hydrophobic drug. The bioavailability agent comprises an ionic detergent comprising a chain of at least 10 carbon atoms or a non-ionic detergent comprising a chain of at least 15 repeating ethylene oxide units or propylene oxide units or a combination of ethylene oxide units and propylene oxide units. The concentration of the bioavailability agent in the medium is sufficient to enhance the bioavailability of the hydrophobic drug.
    Type: Application
    Filed: August 6, 2007
    Publication date: February 12, 2009
    Applicant: DADE BEHRING INC., A CORPORATION OF DELAWARE
    Inventors: Tie Q. Wei, Gerald Siefring, Jr., Christy Schaible, Amy Posey