Patents by Inventor Geraldine Harriman

Geraldine Harriman has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • COMPOUNDS AND METHODS OF USE THEREOF
    Publication number: 20170342054
    Abstract: Indole compounds are disclosed. Also disclosed are methods for using the compounds to treat human and animal disease, pharmaceutical compositions of the compounds, and kits including the compounds.
    Type: Application
    Filed: January 5, 2017
    Publication date: November 30, 2017
    Inventors: Amy Elder, Geraldine Harriman, Silvana Leit, Jie Li, Howard P. Sard, Yiliang Zhang, Douglas Wilson
  • THERAPEUTIC COMPOUNDS AND RELATED METHODS OF USE
    Publication number: 20170217923
    Abstract: Methods of treating disorders using compounds that modulate striatal-enriched tyrosine phosphatase (STEP) are described herein. Exemplary disorders include schizophrenia and cognitive deficit.
    Type: Application
    Filed: March 13, 2017
    Publication date: August 3, 2017
    Inventors: Masaki Suzuki, Kazumi Kondo, Muneaki Kurimura, Krishna Reddy Valluru, Akira Takahashi, Takeshi Kuroda, Haruka Takahashi, Tae Fukushima, Shin Miyamura, Indranath Ghosh, Abhishek Dogra, Geraldine Harriman, Amy Elder, Satoshi Shimizu, Kevin J. Hodgetts, Jason S. Newcom
  • Therapeutic compounds and related methods of use
    Patent number: 9630947
    Abstract: Methods of treating disorders using compounds that modulate striatal-enriched tyrosine phosphatase (STEP), such as those of formula (III), and composition thereof are described herein. Exemplary disorders include schizophrenia and cognitive deficit.
    Type: Grant
    Filed: April 21, 2015
    Date of Patent: April 25, 2017
    Assignee: OTSUKA PHARMACEUTICAL CO., LTD.
    Inventors: Masaki Suzuki, Kazumi Kondo, Muneaki Kurimura, Krishna Reddy Valluru, Akira Takahashi, Takeshi Kuroda, Haruka Takahashi, Tae Fukushima, Shin Miyamura, Indranath Ghosh, Abhishek Dogra, Geraldine Harriman, Amy Elder, Satoshi Shimizu, Kevin J. Hodgetts, Jason S. Newcom
  • THERAPEUTIC COMPOUNDS AND RELATED METHODS OF USE
    Publication number: 20150307477
    Abstract: Methods of treating disorders using compounds that modulate striatal-enriched tyrosine phosphatase (STEP) are described herein. Exemplary disorders include schizophrenia and cognitive deficit.
    Type: Application
    Filed: April 21, 2015
    Publication date: October 29, 2015
    Inventors: Masaki Suzuki, Kazumi Kondo, Muneaki Kurimura, Krishna Reddy Valluru, Akira Takahashi, Takeshi Kuroda, Haruka Takahashi, Tae Fukushima, Shin Miyamura, Indranath Ghosh, Abhishek Dogra, Geraldine Harriman, Amy Elder, Satoshi Shimizu, Kevin J. Hodgetts, Jason S. Newcom
  • COMPOUNDS AND METHODS OF USE THEREOF
    Publication number: 20150284365
    Abstract: Indole compounds are disclosed. Also disclosed are methods for using the compounds to treat human and animal disease, pharmaceutical compositions of the compounds, and kits including the compounds.
    Type: Application
    Filed: November 4, 2014
    Publication date: October 8, 2015
    Applicant: GALENEA CORPORATION
    Inventors: Amy Elder, Geraldine Harriman, Silvana Leit, Jie Li, Howard P. Sard, Yiliang Zhang, Douglas Wilson
  • Therapeutic compounds and related methods of use
    Patent number: 9073890
    Abstract: Compounds, pharmaceutical compositions containing the compounds, and methods of using the compounds to treat a disorder, e.g., schizophrenia and cognitive deficit, in a subject are described herein. The compounds disclosed herein include quinoline and quinazoline-containing compounds that modulate striatal-enriched tyrosine phosphatase (STEP) activity.
    Type: Grant
    Filed: December 30, 2010
    Date of Patent: July 7, 2015
    Assignee: OTSUKA PHARMACEUTICAL CO., LTD.
    Inventors: Masaki Suzuki, Kazumi Kondo, Muneaki Kurimura, Krishna Reddy Valluru, Akira Takahashi, Takeshi Kuroda, Haruka Takahashi, Tae Fukushima, Shin Miyamura, Indranath Ghosh, Abhishek Dogra, Geraldine Harriman, Amy Elder, Satoshi Shimizu, Kevin J. Hodgetts, Jason S. Newcom
  • Compounds and methods of use thereof
    Patent number: 8912220
    Abstract: Indole compounds are disclosed. Also disclosed are methods for using the compounds to treat human and animal disease, pharmaceutical compositions of the compounds, and kits including the compounds.
    Type: Grant
    Filed: August 10, 2010
    Date of Patent: December 16, 2014
    Inventors: Amy Elder, Geraldine Harriman, Silvana Leit, Jie Li, Howard Sard, Yiliang Zhang, Doug Wilson
  • QUINAZOLINES AS THERAPEUTIC COMPOUNDS AND RELATED METHODS OF USE
    Publication number: 20140315886
    Abstract: Methods of treating disorders using compounds (I) that modulate stri-atal-enriched tyrosine phosphatase (STEP) are described herein. Exemplary disorders include schizophrenia and cognitive deficit. Formula (I).
    Type: Application
    Filed: June 28, 2012
    Publication date: October 23, 2014
    Applicant: OTSUKA PHARMACEUTICAL CO., LTD.
    Inventors: Masaki Suzuki, Kazumi Kondo, Muneaki Kurimura, Krishna Reddy Valluru, Akira Takahahi, Takeshi Kuroda, Haruka Takahashi, Tae Fukushima, Shin Miyamura, Indranath Ghosh, Abhishek Dogra, Geraldine Harriman, Amy Elder, Satoshi Shimiza, Kevin J. Hodgetts, Jason S. Newcom
  • THERAPEUTIC COMPOUNDS AND RELATED METHODS OF USE
    Publication number: 20130053341
    Abstract: Methods of treating disorders using compounds that modulate striatal-enriched tyrosine phosphatase (STEP) are de-scribed herein. Exemplary disorders include schizophrenia and cognitive deficit.
    Type: Application
    Filed: December 30, 2010
    Publication date: February 28, 2013
    Inventors: Masaki Suzuki, Kazumi Kondo, Muneaki Kurimura, Krishna Reddy Valluru, Akira Takahashi, Takeshi Kuroda, Haruka Takahashi, Tae Fukushima, Shin Miyamura, Indranath Ghosh, Abhishek Dogra, Geraldine Harriman, Amy Elder, Satoshi Shimizu, Kevin J. Hodgetts, Jason S. Newcom
  • COMPOUNDS AND METHODS OF USE THEREOF
    Publication number: 20110144090
    Abstract: Indole compounds are disclosed. Also disclosed are methods for using the compounds to treat human and animal disease, pharmaceutical compositions of the compounds, and kits including the compounds.
    Type: Application
    Filed: August 10, 2010
    Publication date: June 16, 2011
    Inventors: Amy Elder, Geraldine Harriman, Silvana Leit, Jie Li, Howard Sard, Yiliang Zhang, Doug Wilson
  • CCR9 inhibitors and methods of use thereof
    Publication number: 20080103180
    Abstract: The invention relates to compounds represented by Structural Formula I, which can bind to CCR9 receptors and block the binding of a ligand (e.g., TECK) to the receptors. The invention also relates to a method of inhibiting a function of CCR9, and to the use compounds represented by Structural Formula I in research, therapeutic, prophylactic and diagnostic methods.
    Type: Application
    Filed: October 16, 2007
    Publication date: May 1, 2008
    Applicant: Millennium Pharmaceuticals, Inc.
    Inventors: Paul Fleming, Geraldine Harriman, Zhan Shi, Chen Shaowu
  • CCR9 inhibitors and methods of use thereof
    Publication number: 20070066823
    Abstract: The invention relates to compounds represented by Structural Formula I, which can bind to CCR9 receptors and block the binding of a ligand (e.g., TECK) to the receptors. The invention also relates to a method of inhibiting a function of CCR9, and to the use compounds represented by Structural Formula I in research, therapeutic, prophylactic and diagnostic methods.
    Type: Application
    Filed: November 17, 2006
    Publication date: March 22, 2007
    Inventors: Paul Fleming, Geraldine Harriman, Zhan Shi, Shaowu Chen
  • Chemokine receptor antagonists and methods of use therefor
    Publication number: 20070060592
    Abstract: Disclosed are novel compounds and a method of treating a disease associated with aberrant leukocyte recruitment and/or activation. The method comprises administering to a subject in need an effective amount of a compound represented by: or physiologically acceptable salt thereof.
    Type: Application
    Filed: November 10, 2006
    Publication date: March 15, 2007
    Inventors: Jay Luly, Yoshisuke Nakasato, Etsuo Ohshima, Geraldine Harriman, Kenneth Carson, Shomir Ghosh, Amy Elder, Karen Mattia
  • CCR9 inhibitors and methods of use thereof
    Publication number: 20060167251
    Abstract: The invention relates to compounds represented by Structural Formula I, which can bind to CCR9 receptors and block the binding of a ligand (e.g., TECK) to the receptors. The invention also relates to a method of inhibiting a function of CCR9, and to the use compounds represented by Structural Formula I in research, therapeutic, prophylactic and diagnostic methods.
    Type: Application
    Filed: March 28, 2006
    Publication date: July 27, 2006
    Inventors: Paul Fleming, Geraldine Harriman, Zhan Shi, Shaowu Chen
  • CCR1 antagonists and methods of use therefor
    Publication number: 20050288319
    Abstract: The invention provides compounds having the formula: wherein R1 is halogen. The invention also provides compositions comprising the compounds, and methods of treating diseases or disorders that comprise administering one or more of the compounds to a subject in need thereof. The disclosed compounds have CCR1 antagonist activity.
    Type: Application
    Filed: August 16, 2005
    Publication date: December 29, 2005
    Inventors: Kenneth Carson, Geraldine Harriman
  • Beta-carbolines useful for treating inflammatory disease
    Publication number: 20050239781
    Abstract: This invention provides beta-carboline compounds of formula III-A-aa: wherein Q, G, R1, R2, R3, and R6b are as described in the specification. The compounds are useful for treating diseases such as inflammatory diseases and cancer.
    Type: Application
    Filed: April 8, 2005
    Publication date: October 27, 2005
    Inventors: Michael Hepperle, Julie Liu, Francois Soucy, Prakash Raman, Jeremy Little, Paul Fleming, Dominic Reynolds, Geraldine Harriman
  • Functionalized heterocycles as modulators of chemokine receptor function and methods of use therefor
    Publication number: 20050075348
    Abstract: Disclosed are novel compounds having the formula or a physiologically acceptable salt, amide, ester or prodrug thereof. The compounds can be used to modulate (antagonize, agonize) chemokine receptor function. Also disclosed is a method for treating a patient having an inflammatory disease and/or viral infection comprising administering an effective amount of a compound of Formula I. In particular embodiments, the invention is a method for treating a patient infected with HIV.
    Type: Application
    Filed: November 8, 2004
    Publication date: April 7, 2005
    Applicant: Millennium Pharmaceuticals, Inc.
    Inventors: Geraldine Harriman, Kenneth Carson, Daniel Flynn, Michael Solomon, Yuntao Song, Bharat Trivedi, Bruce Roth, Christine Kolz, Ly Pham, Kuai-lin Sun
  • Chemokine receptor antagonists and methods of use thereof
    Publication number: 20050070549
    Abstract: Disclosed are novel compounds and a method of treating a disease associated with aberrant leukocyte recruitment and/or activation. The method comprises administering to a subject in need an effective amount of a compound represented by: formula (1) or physiologically acceptable salt thereof.
    Type: Application
    Filed: November 13, 2002
    Publication date: March 31, 2005
    Inventors: Jay Luly, Yoshisuke Nakasato, Etsuo Ohshima, Geraldine Harriman, Kenneth Carson, Shomir Ghosh, Amy Elder, Karen Mattia