Patents by Inventor Gerard BOSS

Gerard BOSS has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Cobinamide compounds as a cyanide, sulfide, or methane-thiol antidote
    Patent number: 12005066
    Abstract: Methods and compositions for treating cyanide, sulfide, or methane-thiol exposure in a subject. The compositions may include one or more cobinamide compounds, such as an amino-tetrazole-cobinamide and/or a di-(amino-tetrazole)-cobinamide.
    Type: Grant
    Filed: June 4, 2019
    Date of Patent: June 11, 2024
    Assignees: The Regents of the University of California, The Regents of the University of Colorado
    Inventors: Gerard Boss, Adriano Chan, Matthew Brenner, Sari Brenner Mahon, Vikhyat Bebarta
  • TREATMENT FOR AORTIC ANEURYSMS
    Publication number: 20220305024
    Abstract: Compositions and methods for treatment of aortic disease in a subject in need comprising an effective amount of cobinamide. Aortic diseases include for example aortic aneurysm, aortic dissection, or aortic dilation. Aortic disease can be caused for example by Marfan syndrome or oxidative stress.
    Type: Application
    Filed: June 3, 2020
    Publication date: September 29, 2022
    Inventors: Gerard Boss, Darren Casteel, Hema Rangaswami, Renate Pilz
  • Cobinamide Compounds as a Cyanide, Sulfide, or Methane-Thiol Antidote
    Publication number: 20210213031
    Abstract: Methods and compositions for treating cyanide, sulfide, or methane-thiol exposure in a subject. The compositions may include one or more cobinamide compounds, such as an amino-tetrazole-cobinamide and/or a di-(amino-tetrazole)-cobinamide.
    Type: Application
    Filed: June 4, 2019
    Publication date: July 15, 2021
    Applicants: The Regents of the University of California, The Regents of the university of Colorado
    Inventors: Gerard Boss, Adriano Chan, Matthew Brenner, Sari Brenner Mahon, Vikhyat Bebarta
  • Methods and systems of treating wounds
    Patent number: 10272096
    Abstract: The invention generally relates to methods for treating and/or reducing the severity of a wound in a subject. Provided are wound therapies combining low level light therapy (LLLT) and a nitric oxide (NO) donor to treat and/or reduce the severity of the wound. The LLLT and NO donor may be administered concurrently or sequentially. Also provided are wound treatment systems and kits including a light source and a NO donor, which are administered to a wounded subject. Further provided are pharmaceutical compositions that comprise a NO donor and are formulated to be administered in conjunction with LLLT.
    Type: Grant
    Filed: June 6, 2014
    Date of Patent: April 30, 2019
    Inventors: Michael W. Berns, Ryan M. Spitler, Gerard Boss
  • METHODS AND SYSTEMS OF TREATING WOUNDS
    Publication number: 20160113941
    Abstract: The invention generally relates to methods for treating and/or reducing the severity of a wound in a subject. Provided are wound therapies combining low level light therapy (LLLT) and a nitric oxide (NO) donor to treat and/or reduce the severity of the wound. The LLLT and NO donor may be administered concurrently or sequentially. Also provided are wound treatment systems and kits including a light source and a NO donor, which are administered to a wounded subject. Further provided are pharmaceutical compositions that comprise a NO donor and are formulated to be administered in conjunction with LLLT.
    Type: Application
    Filed: June 6, 2014
    Publication date: April 28, 2016
    Applicant: The Regents of the University of California
    Inventors: Michael W. BERNS, Ryan M. SPITLER, Gerard BOSS