Patents by Inventor Gerburg Wulf

Gerburg Wulf has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • COMPOSITIONS AND METHODS FOR THE TREATMENT OF PROLIFERATIVE DISEASES
    Publication number: 20140235630
    Abstract: The present invention relates to pharmaceutical compositions that contain PI3K inhibitors (e.g., PBKa-specific inhibitors) and PARP inhibitors. The invention also provides methods for the treatment of proliferative diseases such as cancer (e.g., breast cancer) by administering the composition(s) to a subject.
    Type: Application
    Filed: September 28, 2012
    Publication date: August 21, 2014
    Inventors: Gerburg Wulf, Lewis C. Cantley
  • Pin1 as a marker for abnormal cell growth
    Patent number: 8129131
    Abstract: Methods for the use of Pin1 as a marker of abnormal cell growth are disclosed. In one embodiment, the method includes detecting a level of Pin1 to stage an abnormal cell growth, such as breast or prostate cancer. In another embodiment, the method includes evaluating the efficacy of a treatment of an abnormal cell growth, such as cancer, by monitoring the levels of Pin1. In another embodiment, the method includes evaluating the extent of metastasis of abnormal cell growth, such as cancer. The levels of Pin1 can be protein levels or nucleic acid levels.
    Type: Grant
    Filed: July 18, 2008
    Date of Patent: March 6, 2012
    Assignee: Beth Israel Deaconess Medical Center
    Inventors: Kun Ping Lu, Xiao Zhen Zhou, Gerburg Wulf
  • Pin1 as a marker for abnormal cell growth
    Publication number: 20090258352
    Abstract: Methods for the use of Pin1 as a marker of abnormal cell growth are disclosed. In one embodiment, the method includes detecting a level of Pin1 to stage an abnormal cell growth, such as breast or prostate cancer. In another embodiment, the method includes evaluating the efficacy of a treatment of an abnormal cell growth, such as cancer, by monitoring the levels of Pin1. In another embodiment, the method includes evaluating the extent of metastasis of abnormal cell growth, such as cancer. The levels of Pin1 can be protein levels or nucleic acid levels.
    Type: Application
    Filed: July 18, 2008
    Publication date: October 15, 2009
    Inventors: Kun Ping Lu, Xiao Zhen Zhou, Gerburg Wulf
  • Pin1 as a marker for abnormal cell growth
    Publication number: 20050186643
    Abstract: Methods for the use of Pin1 as a marker of abnormal cell growth are disclosed. In one embodiment, the method includes detecting a level of Pin1 to stage an abnormal cell growth, such as breast or prostate cancer. In another embodiment, the method includes evaluating the efficacy of a treatment of an abnormal cell growth, such as cancer, by monitoring the levels of Pin1. In another embodiment, the method includes evaluating the extent of metastasis of abnormal cell growth, such as cancer. The levels of Pin1 can be protein levels or nucleic acid levels.
    Type: Application
    Filed: October 9, 2003
    Publication date: August 25, 2005
    Inventors: Kun Lu, Gerburg Wulf, Xiao Zhou
  • Pin1 as a marker for abnormal cell growth
    Publication number: 20020025521
    Abstract: Methods for the use of Pin1 as a marker of abnormal cell growth are disclosed. In one embodiment, the method includes detecting a level of Pin1 to stage an abnormal cell growth, such as breast or prostate cancer. In another embodiment, the method includes evaluating the efficacy of a treatment of an abnormal cell growth, such as cancer, by monitoring the levels of Pin1. In another embodiment, the method includes evaluating the extent of metastasis of abnormal cell growth, such as cancer. The levels of Pin1 can be protein levels or nucleic acid levels.
    Type: Application
    Filed: November 29, 2000
    Publication date: February 28, 2002
    Inventors: Kun Ping Lu, Gerburg Wulf, Xiao Zhen Zhou