Patents by Inventor Gerd Kleefeld

Gerd Kleefeld has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 9771389
    Abstract: The present invention relates to new macrolide derivatives, in particular new tylosin derivatives of the formula (IIa), a pharmaceutical or veterinary composition comprising the derivatives; a method for preparation thereof; a method for treating and/or preventing bacterial infections in an animal, wherein the method comprises administering the derivatives or the composition; and a use of the derivatives for the manufacture of medicaments for treating and/or preventing bacterial infections in an animal.
    Type: Grant
    Filed: May 23, 2014
    Date of Patent: September 26, 2017
    Assignees: THE KITASAKO INSTITUTE, BAYER ANIMAL HEALTH GMBH
    Inventors: Gerd Kleefeld, Robrecht Froyman, Carolin Ludwig, Satoshi Omura, Toshiaki Sunazuka, Hirose Tomoyasu, Sugawara Akihiro, Shiomi Kazuro
  • Patent number: 9593140
    Abstract: The present invention relates to new macrolide derivatives, in particular new tylosin derivatives of the formula (I); a pharmaceutical or veterinary composition comprising the derivatives; a method for preparation thereof; a method for treating and/or preventing bacterial infections in an animal, wherein the method comprises administering the derivatives or the composition; and a use of the derivatives for the manufacture of medicaments for treating and/or preventing bacterial infections in an animal.
    Type: Grant
    Filed: November 21, 2012
    Date of Patent: March 14, 2017
    Assignee: BAYER INTELLECTUAL PROPERTY GMBH
    Inventors: Gerd Kleefeld, Robrecht Froyman, Julia Charlotte Dörner, Carolin Ludwig, Omura Satoshi, Sunazuka Toshiaki, Hirose Tomoyasu, Sugawara Akihiro, Shiomi Kazuro
  • Publication number: 20160108077
    Abstract: The present invention relates to new macrolide derivatives, in particular new tylosin derivatives of the formula (IIa), a pharmaceutical or veterinary composition comprising the derivatives; a method for preparation thereof; a method for treating and/or preventing bacterial infections in an animal, wherein the method comprises administering the derivatives or the composition; and a use of the derivatives for the manufacture of medicaments for treating and/or preventing bacterial infections in an animal.
    Type: Application
    Filed: May 23, 2014
    Publication date: April 21, 2016
    Applicants: THE KITASAKO INSTITUTE, BAYER ANIMAL HEALTH GMBH
    Inventors: Gerd KLEEFELD, Robrecht FROYMAN, Carolin LUDWIG, Satoshi OMURA, Toshiaki SUNAZUKA, Hirose TOMOYASU, Sugawara AKIHIRO, Shiomi KAZURO
  • Publication number: 20140349954
    Abstract: The present invention relates to new macrolide derivatives, in particular new tylosin derivatives of the formula (I); a pharmaceutical or veterinary composition comprising the derivatives; a method for preparation thereof; a method for treating and/or preventing bacterial infections in an animal, wherein the method comprises administering the derivatives or the composition; and a use of the derivatives for the manufacture of medicaments for treating and/or preventing bacterial infections in an animal.
    Type: Application
    Filed: November 21, 2012
    Publication date: November 27, 2014
    Inventors: Gerd Kleefeld, Robrecht Froyman, Julia Charlotte Dörner, Carolin Ludwig, Satoshi Omura, Sunazuka Toshiaki, Hirose Tomoyasu, Sugawara Akihiro, Shiomi Kazuro
  • Patent number: 7122506
    Abstract: The invention relates to novel cyclic imines of the formula (I) in which Ar1 and Ar2 each represent substituted phenyl and n represents 1, 2, or 3, to a plurality of processes for their preparation and to their use as pesticides.
    Type: Grant
    Filed: January 30, 2004
    Date of Patent: October 17, 2006
    Assignee: Bayer Aktiengesellschaft
    Inventors: Andrew Plant, Gerd Kleefeld, Thorsten Pötter, Christoph Erdelen, Norbert Mencke, Andreas Turberg, Ulrike Wachendorff-Neumann
  • Publication number: 20040186287
    Abstract: The invention relates to novel cyclic imines of the formula (I) 1
    Type: Application
    Filed: January 30, 2004
    Publication date: September 23, 2004
    Inventors: Andrew Plant, Gerd Kleefeld, Thorsten Potter, Christoph Erdelen, Norbert Mencke, Andreas Turberg, Ulrike Wachendorff-Neumann
  • Patent number: 6770595
    Abstract: The invention relates to novel cyclic imines of the formula (I) in which Ar1 and Ar2 each represent substituted phenyl and n represents 1, 2 or 3, to a plurality of processes for their preparation and to their use as pesticides.
    Type: Grant
    Filed: December 19, 2001
    Date of Patent: August 3, 2004
    Assignee: Bayer Aktiengesellschaft
    Inventors: Andrew Plant, Gerd Kleefeld, Thorsten Pötter, Christoph Erdelen, Norbert Mencke, Andreas Turberg, Ulrike Wachendorff-Neumann
  • Publication number: 20020151571
    Abstract: The invention relates to novel cyclic imines of the formula (I) 1
    Type: Application
    Filed: December 19, 2001
    Publication date: October 17, 2002
    Inventors: Andrew Plant, Gerd Kleefeld, Thorsten Potter, Christoph Erdelen, Norbert Mencke, Andreas Turberg, Ulrike Wachendorff-Neumann
  • Patent number: 6399771
    Abstract: The invention relates to novel cyclic imines of the formula (I) in which Ar1 and Ar2 each represent substituted phenyl and n represents 1, 2 and 3, to a plurality of processes for their preparation and to their use as pesticides.
    Type: Grant
    Filed: September 9, 2000
    Date of Patent: June 4, 2002
    Assignee: Bayer Aktiengesellschaft
    Inventors: Andrew Plant, Gerd Kleefeld, Thorsten Pötter, Christoph Erdelen, Norbert Mencke, Andreas Turberg, Ulrike Wachendorff-Neumann
  • Patent number: 6335325
    Abstract: The present application relates to novel acylated 4-amino-pyridine derivatives in which R1, R2, R3, R4, A, X1, X2, m and n are as defined in the description, to process for their separation and to their use for controlling animal pests and as fungicides.
    Type: Grant
    Filed: May 9, 2000
    Date of Patent: January 1, 2002
    Assignee: Bayer Aktiengesellschaft
    Inventors: Thomas Bretschneider, Markus Heil, Bernd Alig, Gerd Kleefeld, Christoph Erdelen, Andreas Turberg, Norbert Mencke
  • Patent number: 6274613
    Abstract: The invention relates to novel cyclic imines of the formula (I) in which Ar1 and Ar2 each represent substituted phenyl and n represents 1, to a process for their preparation and to their use as pesticides.
    Type: Grant
    Filed: May 11, 1999
    Date of Patent: August 14, 2001
    Assignee: Bayer Aktiengesellschaft
    Inventors: Andrew Plant, Gerd Kleefeld, Thorsten Pötter, Christoph Erdelen, Norbert Mencke, Andreas Turberg, Ulrike Wachendorff-Neumann
  • Patent number: 6051589
    Abstract: The invention relates to novel diphenyloxazoline derivatives of the formula (I) ##STR1## in which a) A represents tri- to pentasubstituted phenyl andB represents substituted phenyl orb) A represents mono- or disubstituted phenyl andB represents at least trisubstituted phenyl, but where at least one substituent is not fluorine, chlorine, bromine, C.sub.1 -C.sub.6 -alkyl or -alkoxy,to a number of processes for their preparation and to their use as pest control agents.
    Type: Grant
    Filed: July 9, 1996
    Date of Patent: April 18, 2000
    Assignee: Bayer Aktiengesellschaft
    Inventors: Johannes Kanellakopulos, Gerd Kleefeld, Udo Kraatz, Ulrike Wachendorff-Neumann, Christoph Erdelen, Andreas Turberg, Norbert Mencke
  • Patent number: 6013804
    Abstract: The present invention relates to 1,3,4-oxadiazolin-2-ones of the formula (I) ##STR1## in which Ar.sup.1 represents optionally substituted phenyl andAr.sup.2 represents optionally substituted biphenyl,to processes for their preparation and to their use for controlling animal pests.
    Type: Grant
    Filed: February 20, 1998
    Date of Patent: January 11, 2000
    Assignee: Bayer Aktiengesellschaft
    Inventors: Gerd Kleefeld, Ulrike Wachendorff-Neumann
  • Patent number: 5883091
    Abstract: The invention relates to new 1,3,4-oxadiazine derivatives of the formula (I) ##STR1## in which Ar.sup.1 represents in each case optionally substituted aryl or hetaryl,Ar.sup.2 represents in each case optionally substituted aryl or hetaryl andX represents the group --(CHR.sup.1).sub.m --(CHR.sup.2).sub.n in whichR.sup.1 represents hydrogen or alkyl,R.sup.2 represents hydrogen or alkyl,m represents 0 or 1 andn represents 0 or 1,to a plurality of processes for their preparation, and to their use for combating animal pests.
    Type: Grant
    Filed: June 6, 1997
    Date of Patent: March 16, 1999
    Assignee: Bayer Aktiengesellschaft
    Inventors: Gerd Kleefeld, Johannes Kanellakopulos, Ulrike Wachendorff-Neumann
  • Patent number: 5412100
    Abstract: Fungicidal substituted acrylic esters of the formula ##STR1## in which R.sup.1 represents hydrogen, alkyl or alkenyl, or represents in each case optionally substituted aralkyl, aralkenyl, aryl or heteroaryl,R.sup.2 represents halogen, cyano, nitro, formyl, halogenoalkyl, alkoxyalkyl or alkylthioalkyl, or represents hydroximinoalkyl, alkoximinoalkyl, N-alkyliminoalkyl, N-aryliminoalkyl or N,N-dialkylhydrazonoalkyl, or represents alkoxy, alkylthio, halogenoalkoxy or halogenoalkylthio, or represents aryloxy or arylthio, or represents alkanoyl, alkoxycarbonyl, N,N-dialkylcarbamoyl or heterocyclylcarbonyl,R.sup.3 represents alkyl, or represents optionally substituted aralkyl,R.sup.4 represents dialkylamino or represents a radical --Z--R.sup.5,X represents oxygen or sulphur andY represents oxygen or sulphur or represents a radical ##STR2## where R.sup.5 represents alkyl or represents optionally substituted aralkyl,R.sup.
    Type: Grant
    Filed: July 1, 1993
    Date of Patent: May 2, 1995
    Assignee: Bayer Aktiengesellschaft
    Inventors: Alexander Klausener, Gerd Kleefeld, Wilhelm Brandes, Stefan Dutzmann, Gerd Hanssler
  • Patent number: 5322949
    Abstract: Fungicidal thiadiazole-substituted acrylic acid esters of the formula ##STR1## in which R.sup.1 represents hydrogen, unsubstituted or substituted alkyl or alkenyl, or in each case unsubstituted or substituted aralkyl, aralkenyl, aryl or heteroaryl,R.sup.2 represents alkyl,R.sup.3 represents dialkylamino or a radical --Z--R.sup.4,Y represents oxygen, sulphur or a radical ##STR2## R.sup.4 represents alkyl or unsubstituted or substituted aralkyl, R.sup.5 represents hydrogen or alkyl andZ represents oxygen or sulphur.
    Type: Grant
    Filed: October 6, 1992
    Date of Patent: June 21, 1994
    Assignee: Bayer Aktiengesellschaft
    Inventors: Ulrich Heinemann, Gerd Kleefeld, Stefan Dutzmann, Gerd Hanssler
  • Patent number: 5310919
    Abstract: Fungicidal pyridyl-substituted acrylic esters of the formula ##STR1## in which R.sup.1 represents alkyl or represents optionally substituted aralkyl,R.sup.2 represents dialkylanino or represents a radical --Z--R.sup.3,X represents oxygen or sulphur or represents a radical ##STR2## and Py represents optionally substituted pyridyl, whereR.sup.3 represents alkyl or represents optionally substituted aralkyl,R.sup.4 represents hydrogen, alkyl or alkanoyl or represents in each case optionally substituted aralkyl or aryl andZ represents oxygen or sulphur, their geometric isomers and isomer mixtures.
    Type: Grant
    Filed: January 31, 1992
    Date of Patent: May 10, 1994
    Assignee: Bayer Aktiengesellschaft
    Inventors: Alexander Klausener, Gerd Kleefeld, Dieter Berg, Stefan Dutzmann, Gerd Hanssler
  • Patent number: 5266586
    Abstract: Fungicidal trazoles of the formula ##STR1## in which Ar stands for optionally substituted aryl,A stands for the groups ##STR2## and X stands for the groups ##STR3## wherein R.sup.1 stands for hydrogen or alkyl,R.sup.2 stands for hydrogen or alkyl,R.sup.3 stands for hydrogen, alkyl, alkenyl, alkanoyl, for optionally substituted cycloalkyl or for in each case optionally substituted aralkyl or aroyl,R.sup.4 stands for hydrogen, alkyl, for optionally substituted cycloalkyl or for in each case optionally substituted aralkyl or aryl andR.sup.5 and R.sup.6 independently of one another stand for alkyl or for optionally substituted aralkyl or together stand for an optionally substituted doubly-linked alkylene radical,and addition products thereof with acids and metal salts.
    Type: Grant
    Filed: May 14, 1992
    Date of Patent: November 30, 1993
    Assignee: Bayer Aktiengesellschaft
    Inventors: Gerd Kleefeld, Stefan Dutzmann
  • Patent number: 5254693
    Abstract: Fungicidal substituted acrylic esters of the formula ##STR1## in which R.sup.1 represents hydrogen, alkyl or alkenyl, or represents in each case optionally substituted aralkyl, aralkenyl, aryl or heteroaryl,R.sup.2 represents halogen, cyano, nitro, formyl, halogenoalkyl, alkoxyalkyl or alkylthioalkyl, or represents hydroximinoalkyl, alkoximinoalkyl, N-alkyliminoalkyl, N-aryliminoalkyl or N,N-dialkylhydrazonoalkyl, or represents alkoxy, alkylthio, halogenoalkoxy or halogenoalkylthio, or represents aryloxy or arylthio, or represents alkanoyl, alkoxycarbonyl, N,N-dialkylcarbamoyl or heterocyclylcarbonyl,R.sup.3 represents alkyl, or represents optionally substituted aralkyl,R.sup.4 represents dialkylamino or represents a radical --Z--R.sup.5,X represents oxygen or sulphur andY represents oxygen or sulphur or represents a radical ##STR2## where R.sup.5 represents alkyl or represents optionally substituted aralkyl,R.sup.
    Type: Grant
    Filed: November 5, 1991
    Date of Patent: October 19, 1993
    Assignee: Bayer Aktiengesellschaft
    Inventors: Alexander Klausener, Gerd Kleefeld, Wilhelm Brandes, Stefan Dutzmann, Gerd Hanssler
  • Patent number: 5207817
    Abstract: Herbicidal 5H-furan-2-one derivatives of the formula ##STR1## in which X represents the radical OR.sup.1 or the radical ##STR2## q represents the number 0 or 1, R.sup.2 is optionally substituted aryl, andR.sup.3 and R.sup.6 are hydrogen or various organic radicals,with certain provisos and exceptions.
    Type: Grant
    Filed: October 17, 1991
    Date of Patent: May 4, 1993
    Assignee: Bayer Aktiengesellschaft
    Inventors: Wolfgang Kramer, Gerd Kleefeld, Jurgen Bachmann, Peter Babczinski, Hans-Joachim Santel, Klaus Lurssen, Robert R. Schmidt