Patents by Inventor Gerd Stehle

Gerd Stehle has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Conjugate consisting of an active substance and a non-exogeneous native protein
    Publication number: 20010012885
    Abstract: This invention relates to a conjugate which consists of an active substance and a native protein which is not regarded as exogenous and distinguishes itself in that an intracellularly cleavable linker is present between the active substance and the protein.
    Type: Application
    Filed: April 4, 2001
    Publication date: August 9, 2001
    Applicant: Deutsches Krebsforschungszentrum stiftung des Offentlichen Rechts
    Inventors: Hansjorg Sinn, Hans-Hermann Schrenk, Wolfgang Maier-Borst, Gerd Stehle, Andreas Wunder, Dirk Hoff-Biederbeck, Dieter Ludwig Heene
  • Preparation of acid amides and metallization of compounds
    Patent number: 6177561
    Abstract: The present invention relates to a process for preparing acid amides by reacting an acid with an aliphatic amine in molten urea. This invention also concerns a process for metalating compounds which can be bonded to a metal ion by reacting the compound with a metal ion in molten urea. Furthermore, the invention deals with the thus obtained products and their use for the therapy and/or diagnosis of tumors or inflammatory diseases.
    Type: Grant
    Filed: December 6, 1999
    Date of Patent: January 23, 2001
    Assignee: Deutsches Krebsforschungszentrum Stiftung des Offentlichen Rechts
    Inventors: Hannsjörg Sinn, Wolfgang Maier-Borst, Hans-Hermann Schrenk, Gerd Stehle
  • Conjugate of an active agent, a polyether and possibly a native protein regarded as acceptable by the body
    Patent number: 6150327
    Abstract: This invention relates to the use of a conjugate comprising an active substance and a native protein which is not recognized as foreign protein for the production of a pharmaceutical preparation for treating and/or diagnosing inflammatory, infectious and/or skin diseases.
    Type: Grant
    Filed: October 14, 1997
    Date of Patent: November 21, 2000
    Assignee: Deutsches Krebsforschungszentrum Stiftund des Offentlichen Rechts
    Inventors: Hannsjorg Sinn, Hans-Hermann Schrenk, Wolfgang Maier-Borst, Gerd Stehle
  • Method for producing chlorins and bacteriochlorins containing polyether
    Patent number: 6147207
    Abstract: This invention relates to a process for the preparation of polyether-including chlorins and/or bacteriochlorins, comprising the following steps:(a) bonding a polyether to a porphyrin and(b) reacting the polyether-including porphyrin with a reducing agent.Furthermore, this invention concerns the polyether-including chlorins and bacteriochlorins, obtained by the process, as well as the use thereof for the photodynamic treatment of tumors.
    Type: Grant
    Filed: December 31, 1998
    Date of Patent: November 14, 2000
    Assignee: Deutsches Krebsforschungszentrum Stiftung des Offentlichen
    Inventors: Hannsjorg Sinn, Hans-Hermann Schrenk, Michael Kaus, Wolfgang Maier-Borst, Gerd Stehle
  • Conjugate for treating inflammatory diseases
    Patent number: 5906977
    Abstract: The present invention relates pharmaceutical compositions comprising a conjugate of an active substance, a linker and a carrier for the treatment and/or diagnosis of inflammatory diseases. The present invention further relates to methods using such pharmaceutical compositions for treating and diagnosing inflammatory diseases including, but not limited to, infectious diseases, autoimmune diseases, skin diseases, and inflammatory neovascularization.
    Type: Grant
    Filed: September 23, 1997
    Date of Patent: May 25, 1999
    Assignee: Deutsches Krebsforschungszentrum Stiftung des offentlichen Rechts
    Inventors: Hansjorg Sinn, Hans-Hermann Schrenk, Wolfgang Maier-Borst, Gerd Stehle, Andreas Wunder, Dirk Hoff-Biederbeck, Dieter Ludwig Heene