Patents by Inventor Gerd WIESLER

Gerd WIESLER has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • FOLATE SALTS
    Publication number: 20230416253
    Abstract: The invention relates to crystalline folate salts. The salt consists of a folate anion and an organic cation. The folate anion is 5-methyl-(6S)-tetrahydrofolic acid, and the cation is an organic compound which is an alkanolamine selected from the group consisting of choline, N-methylaminoethanol, 2-amino-2-methylpropanol and 2-dimethylaminoethanol.
    Type: Application
    Filed: September 8, 2023
    Publication date: December 28, 2023
    Applicant: APROFOL AG
    Inventors: Martin Ulmann, Gerd Wiesler, Arthur Bodenmüller, Markus Müller
  • Folate salts
    Patent number: 11787808
    Abstract: The invention relates to crystalline folate salts. The salt consists of a folate anion and an organic cation. The folate anion is 5-methyl-(6S)-tetrahydrofolic acid, and the cation is an organic compound which is an alkanolamine selected from the group consisting of choline, N-methylaminoethanol, 2-amino-2-methylpropanol and 2-dimethylaminoethanol.
    Type: Grant
    Filed: October 31, 2019
    Date of Patent: October 17, 2023
    Assignee: APROFOL AG
    Inventors: Martin Ulmann, Gerd Wiesler, Arthur Bodenmüller, Markus Müller
  • FOLATE SALTS FOR MEDICAL USE
    Publication number: 20230277544
    Abstract: The invention relates to amorphous folate salt. The salt consists of a folate anion and an organic cation. The folate anion is selected from the group consisting of 5-formyl-(6S)-tetrahydrofolic acid, 10-formyl-(6R)-tetrahydrofolic acid, 5-methyl-(6S)-tetrahydrofolic acid, (6S)-tetrahydrofolic acid, 5,10-Methylene-(6R)-tetrahydrofolic acid, and its oxidized derivatives JK12A and Mefox, and the cation is an organic compound selected from the group arginine, choline, acetylcholine, 1,1-dimethyl-biguanidin phenylethylbiguanidin, betaine-methylester and dimethylaminoethanol. The cation is an organic compound with a complementary pharmacological activity.
    Type: Application
    Filed: May 12, 2023
    Publication date: September 7, 2023
    Inventors: Martin ULMANN, Gerd WIESLER, Arthur BODENMÜLLER, Markus MÜLLER
  • Folate salts for medical use
    Patent number: 11690846
    Abstract: The invention relates to amorphous folate salt. The salt consists of a folate anion and an organic cation. The folate anion is selected from the group consisting of 5-formyl-(6S)-tetrahydrofolic acid, 10-formyl-(6R)-tetrahydrofolic acid, 5-methyl-(6S)-tetrahydrofolic acid, (6S)-tetrahydrofolic acid, 5,10-Methylene-(6R)-tetrahydrofolic acid, and its oxidized derivatives JK12A and Mefox, and the cation is an organic compound selected from the group arginine, choline, acetylcholine, 1,1-dimethyl-biguanidin and phenylethylbiguanidin. The cation is an organic compound with a complementary pharmacological activity.
    Type: Grant
    Filed: August 29, 2018
    Date of Patent: July 4, 2023
    Inventors: Martin Ulmann, Gerd Wiesler, Arthur Bodenmüller, Markus Müller
  • FOLATE COMPOSITIONS
    Publication number: 20230158029
    Abstract: A composition is described comprising at least one folate which is useful in the treatment of ocular diseases linked to elevated retinal venous pressure.
    Type: Application
    Filed: February 26, 2021
    Publication date: May 25, 2023
    Applicant: APROFOL AG
    Inventors: Martin Ulmann, Gerd Wiesler, Josef Flammer
  • FOLATE SALTS
    Publication number: 20210403471
    Abstract: The invention relates to crystalline folate salts. The salt consists of a folate anion and an organic cation. The folate anion is 5-methyl-(6S)-tetrahydrofolic acid, and the cation is an organic compound which is an alkanolamine selected from the group consisting of choline, N-methylaminoethanol, 2-amino-2-methylpropanol and 2-dimethylaminoethanol.
    Type: Application
    Filed: October 31, 2019
    Publication date: December 30, 2021
    Applicant: APROFOL AG
    Inventors: Martin Ulmann, Gerd Wiesler, Arthur Bodenmüller, Markus Müller (deceased)
  • FOLATE PREPARATIONS
    Publication number: 20210308139
    Abstract: Preparations of folate for use in the treatment of eye disorders in the presence of elevated intraocular pressure. Methods of reducing intraocular pressure in a patient having an eye disease.
    Type: Application
    Filed: August 29, 2019
    Publication date: October 7, 2021
    Applicant: APROFOL AG
    Inventors: Martin Ulmann, Gerd Wiesler, Josef Flammer
  • FOLATE PREPARATIONS
    Publication number: 20210267982
    Abstract: The present invention relates to preparations of folate salts and their topical use for the treatment of epithelial tissue irritations and skin disorders.
    Type: Application
    Filed: July 1, 2019
    Publication date: September 2, 2021
    Inventors: Martin ULMANN, Gerd WIESLER, Hans DUTLER
  • FOLATE SALTS FOR MEDICAL USE
    Publication number: 20200261460
    Abstract: The invention relates to amorphous folate salt. The salt consists of a folate anion and an organic cation. The folate anion is selected from the group consisting of 5-formyl-(6S)-tetrahydrofolic acid, 10-formyl-(6R)-tetrahydrofolic acid, 5-methyl-(6S)-tetrahydrofolic acid, (6S)-tetrahydrofolic acid, 5,10-Methylene-(6R)-tetrahydrofolic acid, and its oxidized derivatives JK12A and Mefox, and the cation is an organic compound selected from the group arginine, choline, acetylcholine, 1,1-dimethyl-biguanidin and phenylethylbiguanidin. The cation is an organic compound with a complementary pharmacological activity.
    Type: Application
    Filed: August 29, 2018
    Publication date: August 20, 2020
    Inventors: Martin ULMANN, Gerd WIESLER, Arthur BODENMÜLLER, Markus MÜLLER