Abstract: Described are heterobicyclic compounds such as 4,5,6,7-tetrahydrobenzo[b]thiophene-3-carboxylic acid amides, 4,7-dihydro-5H-thieno[2,3-c]thiopyran 3-carboxylic acid amides, 4,7-dihydro-5H-thieno[2,3-c]pyran-3-carboxylic acid amides, or benzo[b]thiophene-3-carboxylic acid amides and pharmaceutically acceptable salts thereof, the use of these derivatives for the prophylaxis and/or treatment of various diseases such as infectious diseases, including mycobacteriainduced infections and opportunistic diseases, prion diseases, immunological diseases, autoimmune diseases, bipolar and clinical disorders, cardiovascular diseases, cell proliferative diseases, diabetes, inflammation, transplant rejections, erectile dysfunction, neurodegenerative diseases and stroke, as well as compositions containing at least one heterobicyclic compound and/or pharmaceutically acceptable salts thereof. Furthermore, reaction procedures for the synthesis of the heterobicyclic compound are disclosed.

Abstract: The present invention relates to 4,6-disubstituted aminopyrimidine derivatives and/or pharmaceutically acceptable salts thereof, the use of these derivatives as pharmaceutically active agents, especially for the prophylaxis and/or treatment of infectious diseases, including opportunistic diseases, prion diseases, immunological diseases, autoimmune diseases, bipolar and clinical disorders, cardiovascular diseases, cell proliferative diseases, diabetes, inflammation, transplant rejections, erectile dysfunction, neurodegenerative diseases and stroke, and pharmaceutical compositions containing at least one of said 4,6-di substituted aminopyrimidine derivatives and/or pharmaceutically acceptable salts thereof.

Abstract: A device for producing sausages having at least two coextrusion heads for co-extruding strands of sausage meat which are encased with a casing material, a joint supply is provided for the sausage meat and/or a joint supply is provided for the casing material, each being connected via individual supply elements to the coextrusion heads. The device permits producing exact products where at least the supply means for the casing material and/or the associated supply elements regulating/controlling the volume and/or the pressure of the casting material flow.

Abstract: The present invention relates to compounds of the general formula (I), processes for their preparation, pharmaceutical compositions containing them as well as their use for the production of pharmaceutical compositions for the treatment of inflammatory diseases.

Abstract: The invention relates to a method for microstructuring an optical waveguide having a first cross-sectional region with a first refractive index, a second cross-sectional region with a second refractive index, and a boundary region in the transition from the first to the second cross-sectional region, in which the optical waveguide is exposed to laser radiation in the form of at least one ultra-short single pulse or a sequence of pulses with a defined energy input, whereby the radiant exposure takes place in such a manner that a modification of at least one optical property of the optical waveguide takes place at at least one defined portion of the boundary region.

Abstract: The present invention relates to compounds of the general formula (I), processes for their preparation, pharmaceutical compositions containing them as well as their use for the production of pharmaceutical compositions for the treatment of inflammatory diseases

Abstract: A method and device are provided for the ultrasonic inoculation of biological cell material. The method and device can be implemented by transmitting ultrasonic energy via a device, that includes an ultrasonic transducer and suitably formed glass fibres coupled thereto, into the immediate vicinity of the cells to be inoculated in a fluid containing the inoculation medium or a tissue aggregation. A simple method for low-cost inoculation of individual cells or cell aggregations with biological molecules and/or with pharmaceutical particles is thereby provided.

Abstract: A device for producing sausages having at least two coextrusion heads for co-extruding strands of sausage meat which are encased with a casing material, a joint supply is provided for the sausage meat and/or a joint supply is provided for the casing material, each being connected via individual supply elements to the coextrusion heads. The device permits producing exact products where at least the supply means for the casing material and/or the associated supply elements regulating/controlling the volume and/or the pressure of the casing material flow.

Abstract: A switch cabinet with a rack that can be closed or is closed by at least one double-walled cabinet door, three side walls, a top wall and a bottom wall, where the side walls each has an internal wall and an external wall and are attached to the rack. With a special angling-off of the internal wall for the side walls and the back wall, a completely sealed and shielded internal space of the switch cabinet is produced, wherein the rigid attachment of the internal walls and the external walls is accomplished from outside the supported interior of the switch cabinet.

Abstract: A memory device is configured to guarantee a high degree of flexibility and a compact construction. To this end, the existing plate line device of the memory device which functions on the basis of a hysteresis process is configured to detect the state of a memory capacitor and hence, the information that is stored.

Abstract: Method for filter selection of binary configured for determining smallest concentration changes in substance mixtures is provided wherein one or a plurality of low-concentration lead components can be reliably detected in the presence of higher-concentration matrix or background components using the selected broad-band binary filters. The spectral power transmitted or reflected by the substance mixture is detected by a plurality of photosensitive detectors which are spectrally broad-banded and provided with binary filters, the detector signals being used for exact determination of the substance concentrations.

Abstract: The present invention relates to compounds of the general formula (I), processes for their preparation, pharmaceutical compositions containing them as well as their use for the production of pharmaceutical compositions for the treatment of inflammatory diseases.

Abstract: The present invention relates to compounds of the general formula (I), 1

Abstract: An electrode arrangement is provided having at least one electrode for insertion into a human or animal body for electrothermal treatment of the body. The electrode is situated on an electrode support and is connected to an alternating current source via a supply lead and to a temperature stabilizer device for influencing the effective temperature profile in a treatment area. The electrode support and the electrode, or electrodes, are constructed for direct insertion into body tissue, said insertion being channel forming. The temperature stabilizer device has a timed heating device.

Abstract: An integrated memory with a configuration of non-volatile memory cells based on ferromagnetic storage contains both powerful memory cells with a magnetoresistive effect with a transistor control and cost-effective memory cells with a magnetoresistive effect with memory elements connected between the word lines and bit lines. The memory elements connected directly between the bit line and the word line are preferably inserted in memory cell arrays that can be stacked one above the other above the memory cells with the transistor, and thereby achieve a high integration density. The fact that the memory, which contains both types and thereby satisfies all the system requirements, is fabricated in one module and in one process sequence considerably lowers the fabrication costs.

Abstract: The present invention relates to a compound of the general formula (I), wherein R1 together with the C atom to which it is attached, and R2 together with the N atom to which it is attached, form a piperidinyl ring; X represents a bond, oxygen or —NR12—; and Y represents oxygen; pharmaceutical compositions containing such a compound, as well as the use of such a compound for the production of pharmaceutical compositions, and for the treatment of inflammatory, auto-immune and immune diseases.

Abstract: The MRAM semiconductor memory configuration has MRAM main cell arrays in the form of a crosspoint array or a transistor array together with redundant MRAM cell arrays formed of redundant MRAM memory cells arranged in a plurality of planes and provided on the same chip. The redundant MRAM cell arrays are distributed over the individual planes of the memory matrix or one plane of the memory array is used in its entirety for providing redundant cell arrays.

Abstract: The invention relates to an apparatus comprising a vacuum filler (3) for stuffing a casing (4) of any kind with a pasty substance and a clip module (1) for applying a clip (2) to a stuffed casing (4). The apparatus is characterized in that the clip module (1) is adapted to be driven by the vacuum filler (3). Furthermore, the invention relates to a method of applying to a casing (4) of any kind a clip (2) by means of a clip module (1), said method comprising the steps of: -stuffing the casing (4) with a pasty substance by means of a vacuum filler (3), -separating the portions, -applying a clip (2) by means of a clip module (1). The method is characterized in that the clip module (1) is driven by the vacuum filler (3).

Abstract: The data memory has a plurality of banks, each with a multiplicity of memory cells that form a matrix of rows and columns with respectively assigned matrix row lines and column lines. The banks are arranged spatially one on top of the other as stacks, with the stack edges that are parallel to the matrix rows and at which the ends of the column lines that are connected to a respective column-driving device are located, lie in a common plane. The common plane extends in the direction of the matrix rows and is substantially orthogonal with respect to the direction of the columns. The column-driving devices of all the banks are arranged directly adjacent to one another as a block in the direction of the columns, on or near the same edge of the bank stack. The banks preferably contain memory cells which can be read out without damage, and in each case a plurality of column lines are each assigned to one common sense amplifier in the column-driving device of each bank.

Abstract: The present invention relates to novel substituted &agr;,&bgr;-fused butyrolactones, to processes for their preparation and to their use for the prevention and/or treatment of disorders caused by hyper- or hypofunction of the glutamatergic system, in particular of cerebral ischaemias, craniocerebral trauma, states of pain or CNS-mediated spasms.