Abstract: A package for enabling a user to mix a diluent with a hazardous material and then fill a syringe with the solution in such a way as to substantially prevent the hazardous material from entering the immediate atmospheric environment comprising a vial and a sealed bag enclosing the entire vial so as to provide exterior sealed containment for the vial in the event of unexpected failure of the vial container and elastomeric stopper assembly to sealingly contain the hazardous material. The vial is sealed within the bag so as to form a space exteriorly of the vial which is controlled by the bag and which is operable to receive any hazardous material in the form of aerosol or droplets that may pass outwardly through the elastomeric stopper assembly as a result of the withdrawal of the syringe needle therefrom and the increased interior gas pressure created within the vial container by the injection of diluent therein.

Abstract: A wet-dry syringe package including a syringe adapted to carry a liquid and a vial carrying a dry medicament with cooperating adapters provided on the syringe and vial for telescoping action whereby the syringe needle will be embedded in the vial stopper when the package is in the storage condition. Further movement of the syringe toward the vial causes the needle end to project through the vial stopper and establish fluid communication between the vial and syringe whereby the dry medicament and liquid are mixed. The mixture is then aspirated into the syringe and the syringe is freed of the package elements for ready use.

Abstract: Benactyzine hydrochloride is stabilized in a mixture of propylene glycol and water. Preferably a small amount of ethanol is present.

Abstract: An additive adapter for use in conjunction with an injector wherein the injector includes a cylindrical body having a rearward open end and a forward end necked inwardly to form an annular lip. The forward end having a central opening of reduced diameter which is closed off by a sealing diaphragm. A plunger is sealingly and slidably fitted in the rearward portion of the body to form a medicament chamber between the sealing means and the plunger. A needle hub is affixed to the annular lip and carries a needle which is in fluid communication with the medicament chamber upon the opening of the sealing diaphragm. The additive adapter comprises a main body portion including a cylindrical skirt portion extending from the rearward end of the cylindrical sleeve. The skirt is sized to snugly engage and fit over the forward portion of the injector's cylindrical body. A cylindrical shield having a diameter larger than the cylindrical sleeve extends from the forward end thereof.

Abstract: An I.V. injector having a cylindrical barrel open at one end and closed at the other end by sealing means, a cannula mounted on the closed end outwardly from the sealing means, a plunger slidably carried in the open end of the barrel, a chamber formed in the barrel between the plunger and the sealing means, said chamber being adapted to receive a high concentrate I.V. medicament, and a safety member on the closed end of the barrel to render the injector impractical for use in intravenous injection of the I.V. medicament into a patient.