Abstract: The invention relates to methods for the treatment or alleviation of an anterior corneal disorder in a subject in need thereof comprising removing corneal epithelial cells from an eye of said subject without removing any corneal tissue or other ocular tissue located posterior to the corneal epithelial cell layer; and positioning an overlay comprising a Bowman layer (BL), Descemet membrane (DM) and/or crystalline lens capsule on the anterior surface of said corneal tissue located posterior to the corneal epithelial cell layer. The invention further relates to freeze-dried and/or gamma irradiated Bowman layer, Descemet membrane and/or crystalline lens capsule and compositions comprising the same that are useful in such methods.

Abstract: A device provides remote ophthalmic examinations and includes one, plural or all of the following capabilities: slit lamp examinations, visual acuity examinations, fundoscopy, and eye pressure assessment. Preferred devices enable a patient to self-align or adjust device themselves without the help of a professional, collect and store data and can transmit data when a connection is available to a professional or an analysis system, such as a machine learning system, for evaluation.

Abstract: The invention is directed to a visualizing agent comprising a polyoxazoline molecule and one or more labeling compounds. The visualizing agent can be an ocular staining composition that can be used to stain the vitreous body.

Abstract: A staining composition is provided with improved staining intensity. The composition comprises a vital dye and hyaluronic acid, wherein the vital dye comprises Chicago Sky Blue and Trypan Blue. The staining composition is used to stain the lens capsule during cataract surgery and provides sufficient contrast such that no air bubble needs to be injected in the anterior chamber during cataract surgery.

Abstract: The invention is directed to a staining composition and to the use of the staining composition in staining ocular tissue. In a first aspect, the invention provides a staining composition comprising a vital dye and a density increasing compound chosen from the group consisting of water soluble polymers and small inert molecules.

Abstract: The invention is directed to a staining composition and to the use of the staining composition in staining ocular tissue. In a first aspect, the invention provides a staining composition comprising a vital dye and a density increasing compound chosen from the group consisting of water soluble polymers and small inert molecules.

Abstract: The invention is directed to a staining composition and to the use of the staining composition in staining ocular tissue. In a first aspect, the invention provides a staining composition comprising a vital dye and a density increasing compound chosen from the group consisting of water soluble polymers and small inert molecules.

Abstract: The invention is directed to a staining composition and to the use of the staining composition in staining ocular tissue. In a first aspect, the invention provides a staining composition comprising a vital dye and a density increasing compound chosen from the group consisting of water soluble polymers and small inert molecules.

Abstract: The invention relates to a visco-elastic composition for use in ocular surgery and to a method of using said composition. Specifically, the present visco-elastic composition comprises a visco-elastic substance and at least one vital dye. The invention enables a visual distinction of the visco-elastic composition from the surrounding aqueous or intraocular structures during ocular surgery, so that the amount present within the eye, the location and the effects of the visco-elastic material can be better monitored.

Abstract: A method for performing retinal membrane removal is disclosed using vital dyes which are applied to the membrane. Compositions including vital dyes which are useful in the retinal membrane removal methods are also disclosed.

Abstract: The invention relates to a visco-elastic composition for use in ocular surgery and to a method of using said composition. Specifically, the present visco-elastic composition comprises a visco-elastic substance and at least one vital dye. The invention enables a visual distinction of the visco-elastic composition from the surrounding aqueous or intraocular structures during ocular surgery, so that the amount present within the eye, the location and the effects of the visco-elastic material can be better monitored.